Results 31 to 40 of about 894 (94)

Hydrogen Sulfide Promotes TAM‐M1 Polarization through Activating IRE‐1α Pathway via GRP78 S‐Sulfhydrylation to against Breast Cancer

Advanced Science, Volume 12, Issue 8, February 24, 2025.
This work indicates that GRP78 S‐sulfhydrylation mediated by H2S at Cys420 residue decreases tumor burden and inhibits lung metastasis of BC through reprogramming TAMs via activating IRE‐1α pathway, which offers new leads for interventions in TAMs reprogramming in BC.
Mingyi Ju, Weiwei Tong, Jia Bi, Xianxin Zeng, Aoshuang Qi, Mingli Sun, Jian Wen, Lin Zhao, Minjie Wei   +8 more
wiley   +1 more source

Bacterial volatile organic compounds supplemented with light‐emitting diode lighting enhance antioxidant capacity and delay senescence in broccoli

Food Frontiers, Volume 6, Issue 1, Page 448-464, January 2025.
Bacterial volatile organic compounds (BVOCs) are biological volatiles that can have a positive effect on the postharvest preservation of fruits and vegetables. In the present study, fumigation of broccoli with BVOCs released by Lysinibacillus fusiformis supplemented with LED white light irradiation reduced the accumulation of reactive oxygen species ...
Taishan Huang, Junyan Shi, Xiaozhen Yue, Shuzhi Yuan, Xiangbin Xu, Jinhua Zuo, Qing Wang   +6 more
wiley   +1 more source

Xiaoyu Xiezhuo Decoction Improves Diabetic Kidney Disease by Regulating Cysteine and Methionine Metabolism

Journal of Diabetes Research, Volume 2025, Issue 1, 2025.
Background: Diabetic kidney disease (DKD) is a major complication of diabetes mellitus and has emerged as a significant global public health concern. In this study, we aimed to evaluate the therapeutic effects of the traditional Chinese medicine compound formula, Xiaoyu Xiezhuo decoction (XXD), in a DKD mouse model and to explore its underlying ...
Yuancheng Gao, Yue Ji, Xiang Zhang, Qi Liu, Xinnan Jin, Jiawen Qian, Ziyang Wu, Xiangfu Gao, Shouci Hu, Hongbo Chen, Huantian Cui   +10 more
wiley   +1 more source

Beyond Hydrogen Sulfide and Cysteine Metabolism: Reframing Cystathionine γ-Lyase as a Potential Translational Regulator of Hypoxia-Inducible Factor-1α in Clear Cell Ovarian Carcinoma. [PDF]

Cells
El-Naggar AM.
europepmc   +1 more source

Co-targeting cystathionine gamma-lyase and mTOR: a promising therapeutic strategy in clear cell ovarian cancer. [PDF]

BMC Cancer
Wei L, El-Naggar AM, Li Y, Ding Y, Li E, Lam T, Wang Y, Turgu B, Huntsman DG.   +8 more
europepmc   +1 more source

In vivo characterization of the redox balance in IDH-wildtype glioblastomas: a J-difference edited MEGA-sLASER MRS study at 3T. [PDF]

Cancer Metab
Alcicek S, Manzhurtsev A, Thomas DC, Divé I, Weber KJ, Prinz V, Jussen D, Deelchand DK, Oeltzschner G, Ronellenfitsch MW, Steinbach JP, Hattingen E, Pilatus U, Wenger KJ.   +13 more
europepmc   +1 more source

Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression. [PDF]

J Med Chem
Luo Z, Xu G, Li C, Sun Z, Chen H, Yang M, Ye Y, Chen Q, Xu B, Luo H, Sun B.   +10 more
europepmc   +1 more source

Endothelial cystathionine-γ-lyase (CTH) regulates body weight and insulin resistance in mice fed a high-fat diet. [PDF]

Redox Biol
Yagi T, Alam S, Niti SI, Pardue S, Shen X, Glawe JD, Kolluru GK, Tanaka T, Kevil CG.   +8 more
europepmc   +1 more source

Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis. [PDF]

Proc Natl Acad Sci U S A
Chakraborty S, Jamuna Tripathi S, Vázquez-Rosa E, Chaubey K, Fujioka H, Miller E, Tyagi R, Vignane T, Sharma SM, Thomas B, Weil ZM, Nelson RJ, Filipovic MR, Orsburn BC, Snyder SH, Pieper AA, Paul BD.   +16 more
europepmc   +1 more source

Cystathionine gamma-lyase as an inflammatory factor and its link with immune inflammation in hepatitis B virus-related liver disease. [PDF]

Sci Rep
Jin C, Hu B, Liu H, Wang R, Jang J, Su M.   +5 more
europepmc   +1 more source