Results 51 to 60 of about 1,391 (117)
Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway [PDF]
, 2017 Coenzyme Q (CoQ) is an electron acceptor for sulfide‐quinone reductase (SQR), the first enzyme of the hydrogen sulfide oxidation pathway. Here, we show that lack of CoQ in human skin fibroblasts causes impairment of hydrogen sulfide oxidation ...
Barca, Emanuele +7 more
core +1 more source
Voltage-gated K+ (Kv) channels and control visceral arteries tone by perivascular adipose tissue [PDF]
, 2019 Background: Perivascular adipose tissue (PVAT), is now recognized as dynamic paracrine organ and important metabolic sensor. PVAT regulates vascular function by releasing perivascular adipose relaxing factors (PVRFs), particularly a transferable ...
Wang, Ning
core +1 more source
MedComm, Volume 6, Issue 9, September 2025.Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia +4 more
wiley +1 more source
Hydrogen sulfide biosynthesis is impaired in the osteoarthritic joint [PDF]
, 2019 [Abstract] Osteoarthritis (OA) is the most common form of arthritis and it is a leading cause of disability in the elderly. Its complete etiology is not known although there are several metabolic, genetic, epigenetic, and local contributing factors ...
Blanco García, Francisco J +5 more
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Ferroptosis in Pneumoconiosis: From Molecular and Cellular Mechanisms to Therapeutic Strategies
Med Research, Volume 1, Issue 2, Page 239-256, September 2025.Targeting lung various cells to alleviate pneumoconiosis by suppressing ferroptosis. AAV9‐HGF, adeno‐associated virus‐hepatocyte growth factor; DFP, deferiprone; DHQ, dihydroquercetin; Fer‐1, ferrostatin‐1; IL‐1β, interleukin‐1β; NMN, nicotinamide mononucleotide; sh‐SLC39A14, shRNA targeting solute carrier family 39 member 14; si‐OC‐STAMP, siRNA ...
Mengli Yan +4 more
wiley +1 more source
Advanced Science, Volume 12, Issue 8, February 24, 2025.This work indicates that GRP78 S‐sulfhydrylation mediated by H2S at Cys420 residue decreases tumor burden and inhibits lung metastasis of BC through reprogramming TAMs via activating IRE‐1α pathway, which offers new leads for interventions in TAMs reprogramming in BC.
Mingyi Ju +8 more
wiley +1 more source
Food Frontiers, Volume 6, Issue 1, Page 448-464, January 2025.Bacterial volatile organic compounds (BVOCs) are biological volatiles that can have a positive effect on the postharvest preservation of fruits and vegetables. In the present study, fumigation of broccoli with BVOCs released by Lysinibacillus fusiformis supplemented with LED white light irradiation reduced the accumulation of reactive oxygen species ...
Taishan Huang +6 more
wiley +1 more source
ON THE ROLE OF CYSTATHIONINE-γ-LYASE IN MODULATING TRANSSULFURATION PATHWAY IN THE LENS [PDF]
In Mammals transsulfuration pathway enables the conversion of homocysteine (Hcy), deriving from methionine (Met) transmetilation, into cysteine (Cys) through two steps, the first catalyzed by cystathionine β-synthase (CBS) and the second one by ...
CALVANI, ENRICA
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Journal of Diabetes Research, Volume 2025, Issue 1, 2025.Background: Diabetic kidney disease (DKD) is a major complication of diabetes mellitus and has emerged as a significant global public health concern. In this study, we aimed to evaluate the therapeutic effects of the traditional Chinese medicine compound formula, Xiaoyu Xiezhuo decoction (XXD), in a DKD mouse model and to explore its underlying ...
Yuancheng Gao +10 more
wiley +1 more source
Evaluating the modulation of the intracellular production of H2S in the functionality and metabolic activity of primary cultures of pancreatic islets [PDF]
, 2022 Diabetes Mellitus is a metabolic disease characterized by hyperglycaemia that currently affects one in ten people worldwide. Uncontrolled Diabetes is associated with long-term damage and dysfunction and failure of different organs.
Pino Pérez, Inmaculada
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