Results 121 to 130 of about 4,192 (151)

Cystathionine γ‐lyase of Saccharomyces cerevisiae: Structural gene and cystathionine γ‐synthase activity

Yeast, 1993
AbstractPurification of Saccharomyces cerevisiae cystathionine γ‐lyase (γ‐CTLase) was hampered by the presence of a protein migrating very close to it in various types of column chromatography. The enzyme and the contaminant were nevertheless separated by polyacrylamide gel electrophoresis.
B, Ono, N, Ishii, K, Naito, S, Miyoshi, S, Shinoda, S, Yamamoto, S, Ohmori   +6 more
openaire   +2 more sources

Regulation of cystathionine γ‐lyase in Saccharomyces cerevisiae

Yeast, 1991
AbstractRegulation of the two enzymes in reverse trans‐sulfuration was investigated in Saccharomyces cerevisiae. In wild‐type strains, cystathionine γ‐lyase, but not cystathionine β‐synthase, was derepressed nearly 15‐fold if cells were starved for both inorganic and organic sulfur compounds. In a met17 strain which is defective of O‐acetylserine and O‐
B, Ono, K, Naito, Y, Shirahige, M, Yamamoto   +3 more
openaire   +2 more sources

Age-Dependent Allergic Asthma Development and Cystathionine Gamma-Lyase Deficiency

Antioxidants & Redox Signaling, 2017
Aims: The pathogenic mechanisms for the higher prevalence of allergic asthma in children than in adults have not been settled. The aim of the present study is to examine whether the age-dependent development of allergic asthma is caused by age-dependent expression of cystathionine gamma ...
Peipei, Wang, Lingyun, Wu, Yongjun, Ju, Ming, Fu, Tian, Shuang, Zhongming, Qian, Rui, Wang   +6 more
openaire   +2 more sources

Cystathionine gamma‐lyase aggravates periodontal damage in traumatic occlusion mouse models

Journal of Periodontal Research, 2020
AbstractBackground and objectiveThough impacts of traumatic occlusion (TO) on periodontal tissues and roles of cystathionine γ‐lyase (Cth) gene in the regulation of bone homeostasis have been studied by many, no consensus has been reached so far on whether TO deteriorates the periodontium and precise roles of Cth in occlusal trauma.
Liyuan Chen, Caizhu Lu, Yongmei Hua
openaire   +2 more sources

P35 Exacerbation of the septic response in cystathionine-gamma-lyase deficient mice

Nitric Oxide, 2014
Previous studies reported both beneficial and detrimental roles of hydrogen sulfide (H2S) in various models of critical illness. The goal of our study was to compare the outcome of septic shock in wild-type mice and in mice deficient in cystathionine-gamma-lyase (CSE).
Ciro Coletta, Csaba Szabo
openaire   +1 more source

Cystathionine gamma-lyase deficiency exaggerates diethylnitrosamine-induced liver damage in mice

Nitric Oxide - Biology and Chemistry
Cystathionine gamma-lyase (CSE) is a key enzyme in reverse transsulfuration pathway and contributes to the majority of H2S generation in liver tissues via cysteine metabolism. Dysfunction of the CSE/H2S system is linked to both chronic and acute liver damage.
Guangdong Yang
exaly   +3 more sources

Cystathionine Gamma-Lyase: A Potential Longevity Gene Under Selection?

Journal of Molecular Evolution
Hydrogen sulfide (H2S) plays a crucial role in various physiological processes and has been implicated in modulating aging through its impacts on oxidative stress and cellular health. This study investigates the evolutionary dynamics of the cystathionine-β-synthase (CBS), the cystathionine-ƴ-lyase (CSE), and the 3-mercaptopyruvate sulfurtransferase (3 ...
Gary J. Ren, Frances E. Hauser, Elissa Khodikian, Nathan R. Lovejoy, Cosima S. Porteus   +4 more
openaire   +2 more sources

Suicide inactivation of bacterial cystathionine .gamma.-synthase and methionine .gamma.-lyase during processing of L-propargylglycine

Biochemistry, 1979
L-Propargylglycine, a naturally occurring gamma, delta-acetylenic alpha-amino acid, induces mechanism-based inactivation of two pyridoxal phosphate dependent enzymes of methionine metabolism: (1) cystathionine gamma-synthease, which catalyzes a gamma-replacement reaction in methionine biosynthesis, and (2) methionine gamma-lyase, which catalyzes a ...
M, Johnston, D, Jankowski, P, Marcotte, H, Tanaka, N, Esaki, K, Soda, C, Walsh   +6 more
openaire   +2 more sources

Cystathionine gamma lyase expression/activity delays endothelial senescence

Free Radical Biology and Medicine, 2022
Sofia Bibli, Jiong Hu, Matthias Leisegang, Ilka Wittig, Ralf Brandes, Andreas Papapetropoulos, Fragiska Sigala, Ingrid Fleming   +7 more
openaire   +1 more source

Cystathionine gamma-lyase

1990
Dietmar Schomburg, Margit Salzmann
openaire   +1 more source