Results 61 to 70 of about 7,579 (227)

Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages. [PDF]

open access: yes, 2016
Published onlineJOURNAL ARTICLEAIMS: Macrophages are of key importance for tissue repair after myocardial infarction (MI). Hydrogen sulfide (H2S) has been shown to exert cardioprotective effects in MI.
Miao, L   +7 more
core   +1 more source

1,25‐dihydroxyvitamin D 3 influences cellular homocysteine levels in murine preosteoblastic MC3T3‐E1 cells by direct regulation of cystathionine β‐synthase [PDF]

open access: yes, 2011
High homocysteine (HCY) levels are a risk factor for osteoporotic fracture. Furthermore, bone quality and strength are compromised by elevated HCY owing to its negative impact on collagen maturation.
Boonen   +40 more
core   +3 more sources

Two-photon ratiometric imaging of endogenous reactive inorganic sulfur species in the cellular cushion toward formaldehyde

open access: yesBiosensors and Bioelectronics: X, 2023
To address the potential biological relationship between reactive inorganic sulfur species (RISSs) and formaldehyde, the novel two-photon ratiometric RISSs probes (PH-RISSs) were synthesized practically with high selectivity and sensitivity toward RISSs ...
Linye Wu   +9 more
doaj   +1 more source

Transcriptional regulation of Saccharomyces cerevisiae CYS3 encoding cystathionine γ-lyase [PDF]

open access: yesCurrent Genetics, 2008
In studying the regulation of GSH11, the structural gene of the high-affinity glutathione transporter (GSH-P1) in Saccharomyces cerevisiae, a cis-acting cysteine responsive element, CCGCCACAC (CCG motif), was detected. Like GSH-P1, the cystathionine gamma-lyase encoded by CYS3 is induced by sulfur starvation and repressed by addition of cysteine to the
Hiraishi, Hiroyuki   +2 more
openaire   +2 more sources

Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers [PDF]

open access: yes, 2013
Background Trypanosomatids of the genera Angomonas and Strigomonas live in a mutualistic association characterized by extensive metabolic cooperation with obligate endosymbiotic Betaproteobacteria.
Alves, João M.P.   +10 more
core   +5 more sources

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

open access: yesBiology Open, 2015
In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide.
Hua Jiang   +6 more
doaj   +1 more source

Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics [PDF]

open access: yes, 2016
Therapeutic manipulation of the gasotransmitter hydrogen sulfide (H(2)S) has recently been proposed as a novel targeted anticancer approach. Here we show that human lung adenocarcinoma tissue expresses high levels of hydrogen sulfide (H(2)S) producing ...
Druzhyna, Nadiya   +7 more
core   +1 more source

H2S biosynthesis and catabolism: new insights from molecular studies [PDF]

open access: yes, 2017
Hydrogen sulfide (H2S) has profound biological effects within living organisms and is now increasingly being considered alongside other gaseous signalling molecules, such as nitric oxide (NO) and carbon monoxide (CO).
A Asimakopoulou   +272 more
core   +2 more sources

Volatile Sulfur Compounds as a Predictor for Esophagogastroduodenal Mucosal Injury

open access: yesGut and Liver, 2008
Background/Aims: Halitosis is a symptom that bothers patients more socially than medically and its pathogenic mechanisms are unclear and treatment armamenterium is limited. Clinicians generally ignored active interventions.
doaj   +1 more source

Cystathionine .GAMMA.-lyase activity in the cephamycin C producer Streptomyces lactamdurans.

open access: yesThe Journal of Antibiotics, 1981
Extracts of the cephamycin C producer S. lactamdurans were found to possess cystathionine gamma-lyase activity (E.C. 4.4.1.1). This represents the first demonstration of this enzyme of the reverse transsulfuration pathway in a prokaryotic organism. A likely involvement of reverse transsulfuration in antibiotic synthesis is indicated by the fact that ...
B A, Kern, E, Inamine
openaire   +3 more sources

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