Results 31 to 40 of about 55,204 (241)

Parasite Cystatin: Immunomodulatory Molecule with Therapeutic Activity against Immune Mediated Disorders

Pathogens, 2020
The use of parasites or their products for treating chronic inflammation associated diseases (CIADs) has generated significant attention recently. Findings from basic and clinical research have provided valuable information on strengthening the notion ...
Vishal Khatri, Nikhil Chauhan, Ramaswamy Kalyanasundaram   +2 more
doaj   +1 more source

Identification of Proteins Responsible for High Activity of Cysteine Proteinase Inhibitor in the Blood of Nile Tilapia Oreochromis niloticus

Fishes, 2022
Cysteine proteinase inhibitors (CPIs) protect tissues and organs against cysteine proteinases in animal blood and have attracted much attention for use in food processing and medical sciences for humans and animals.
Seong Hee Mun, Joon Yeong Kwon
doaj   +1 more source

Expression of a barley cystatin gene in maize enhances resistance against phytophagous mites by altering their cysteine-proteases [PDF]

, 2011
Phytocystatins are inhibitors of cysteine-proteases from plants putatively involved in plant defence based on their capability of inhibit heterologous enzymes.
A Kiggundu, AH Christensen, AJ Nisbet, APO Ribeiro, B Taylor, BA Croft, C Girard, C Novillo, CJ Lilley, D Michaud, EC Oerke, F Alvarez-Alfageme, F Alvarez-Alfageme, F Ortego, Felix Ortego, G Hueros, GZ Rovenska, HRK McCafferty, HRK McCafferty, Inés Cambra, Isabel Díaz, J Fabrick, K Ramessar, KA Hamilton, Koreen Ramessar, L Oñate-Sanchez, Laura Carrillo, LB Obrist, LR Jeppson, M Castagnoli, M Martinez, M Martinez, M Martinez, M Martinez, M Pernas, M Pernas, Manuel Martinez, MM Bradford, MS Lantz, MS Nissen, MT Stubbs, P Lara, Pedro Castañera, R Gutierrez-Campos, R Konrad, R Margis, S Carbonelle, S Lalitha, Y Li, Z Abraham   +49 more
core   +2 more sources

Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystatin

Frontiers in Cellular and Infection Microbiology, 2020
Schistosomula (the post-infective stages) of the neurotropic schistosome Trichobilharzia regenti possess multiple isoforms of cathepsin B1 peptidase (TrCB1.1-TrCB1.6) with involvement in nutrient digestion.
Hana Dvořáková, Roman Leontovyč, Tomáš Macháček, Anthony J. O'Donoghue, Ondřej Šedo, Zbyněk Zdráhal, Charles S. Craik, Conor R. Caffrey, Petr Horák, Libor Mikeš   +9 more
doaj   +1 more source

Genetic control of plasticity of oil yield for combined abiotic stresses using a joint approach of crop modeling and genome-wide association [PDF]

, 2017
Understanding the genetic basis of phenotypic plasticity is crucial for predicting and managing climate change effects on wild plants and crops. Here, we combined crop modeling and quantitative genetics to study the genetic control of oil yield plasticity for multiple abiotic stresses in sunflower. First we developed stress indicators to characterize
arxiv   +1 more source

Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]

, 2003
Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Brew K., Kitts P.A., Kos J., Kotzsch M., Lah T.T., Magdolen U., Possee R.D., Rabbani S.A., Reuning U., Stetler-Stevenson W.G., Szpaderska A.M., Thomas C.J.   +11 more
core   +2 more sources

An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6

Frontiers in Immunology, 2018
Ticks, blood-feeding arthropods, and secrete immunosuppressive molecules that inhibit host immune responses and provide survival advantages to pathogens.
Ta Sun, Fanqi Wang, Wen Pan, Qihan Wu, Jingwen Wang, Jianfeng Dai   +5 more
doaj   +1 more source

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

Hepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino, Salvatore Piano, Matteo Stenico, Marta Tonon, Alessandra Brocca, Valeria Calvino, Simone Incicco, Nicola Zeni, Roberta Gagliardi, Chiara Cosma, Martina Zaninotto, Patrizia Burra, Umberto Cillo, Daniela Basso, Paolo Angeli   +14 more
wiley   +1 more source

Assessment of Renal Function in Women with Preeclampsia by Measuring of Serum Cystatin C Level

Mustansiriya Medical Journal
Background: Preeclampsia (PE) is a major health problem that increases the risk of renal impairment during pregnancy. Studies have described the utility of Cystatin C as a better indicator of kidney function during pregnancy compared to urea, creatinine,
Marwa Basim Yarmurad, Miami Abdul Hassan Ali   +1 more
doaj   +1 more source

Comparing Results of Five Glomerular Filtration Rate-Estimating Equations in the Korean General Population. MDRD Study, Revised Lund-Malmö, and Three CKD-EPI Equations [PDF]

, 2016
Estimated glomerular filtration rate (eGFR) is a widely used index of kidney function. Recently, new formulas such as the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations or the Lund-Malmö equation were introduced for assessing eGFR.
Han-Ik Cho, Hyesun Kim, Hyun Suk Yang, Mina Hur, Misuk Ji, null null, Salvatore Di Somma, Silvia Navarin, Yoon-Hee Lee   +8 more
core   +1 more source