Results 31 to 40 of about 41,311 (257)

Fetuin-A – Alpha2-Heremans-Schmid Glycoprotein: From Structure to a Novel Marker of Chronic Diseases Part 1. Fetuin-A as a Calcium Chaperone and Inflammatory Marker [PDF]

Journal of Biomedical & Clinical Research, 2018
Fetuin-A is a major plasma glycoprotein released mainly by the liver. Its functions include inhibition of the activity of insulin receptor, regulation of response to inflammation, inhibition of calcified matrix metabolism and ectopic mineralization, etc.
Regina Komsa-Penkova, Georgi Golemanov, Zdravka Radionova, Pencho Tonchev, Sergej Iliev, Veselin Penkov   +5 more
doaj   +3 more sources

Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V

Frontiers in Genetics, 2021
Keratosis follicularis spinulosa decalvans (KFSD) is a rare cornification disorder with an X-linked recessive inheritance in most cases. Pathogenic variants causing X-linked KFSD have been described in MBTPS2, the gene for a membrane-bound zinc ...
Katja M. Eckl, Robert Gruber, Louise Brennan, Andrew Marriott, Roswitha Plank, Roswitha Plank, Verena Moosbrugger-Martinz, Stefan Blunder, Anna Schossig, Janine Altmüller, Holger Thiele, Peter Nürnberg, Johannes Zschocke, Hans Christian Hennies, Hans Christian Hennies, Matthias Schmuth   +15 more
doaj   +1 more source

Melia azedarach L. extract induced the production of phytocystatin in passion fruit leaves

Hoehnea, 2021
Phytocystatins belong to the family of cysteine proteinases inhibitors. These proteinase inhibitors have crucial functions in plant defense against insects and pathogens attack. In the present study Melia azedarach L. extract acts as an elicitor of plant
Alyne Bispo Rodrigues, César Luis Siqueira Junior   +1 more
doaj   +1 more source

Identification of Proteins Responsible for High Activity of Cysteine Proteinase Inhibitor in the Blood of Nile Tilapia Oreochromis niloticus

Fishes, 2022
Cysteine proteinase inhibitors (CPIs) protect tissues and organs against cysteine proteinases in animal blood and have attracted much attention for use in food processing and medical sciences for humans and animals.
Seong Hee Mun, Joon Yeong Kwon
doaj   +1 more source

Overexpression of StCYS1 gene enhances tolerance to salt stress in the transgenic potato (Solanum tuberosum L.) plant

Journal of Integrative Agriculture, 2020
Salt stress seriously restricts the growth and yield of potatoes. Plant cystatins are vital players in biotic stress and development, however, their roles in salt stress resistance remain elusive.
Min-min LIU, Ya-lun LI, Guang-cun LI, Tian-tian DONG, Shi-yang LIU, Pei LIU, Qing-guo WANG   +6 more
doaj   +1 more source

Assessment of Renal Function in Women with Preeclampsia by Measuring of Serum Cystatin C Level

Mustansiriya Medical Journal
Background: Preeclampsia (PE) is a major health problem that increases the risk of renal impairment during pregnancy. Studies have described the utility of Cystatin C as a better indicator of kidney function during pregnancy compared to urea, creatinine,
Marwa Basim Yarmurad, Miami Abdul Hassan Ali   +1 more
doaj   +1 more source

An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6

Frontiers in Immunology, 2018
Ticks, blood-feeding arthropods, and secrete immunosuppressive molecules that inhibit host immune responses and provide survival advantages to pathogens.
Ta Sun, Fanqi Wang, Wen Pan, Qihan Wu, Jingwen Wang, Jianfeng Dai   +5 more
doaj   +1 more source

Correlation between serum homocysteine level and clinicopathological factors of IgA nephropathy

Linchuang shenzangbing zazhi
ObjectiveTo investigate the correlation between serum homocysteine （Hcy） and clinicopathologic factors of immunoglobulin A nephropathy （IgAN）.MethodsA total of 349 patients with IgAN diagnosed by renal biopsy in the Nephrology Department of Longhua ...
Cai Xiao-fan, Huang Jie-bo, Xing Yue, Cai Xiu-feng, Li Xue-ling, Zhong Yi-fei   +5 more
doaj   +1 more source

Cystatins in Immune System [PDF]

Journal of Cancer, 2013
Cystatins comprise a large superfamily of related proteins with diverse biological activities. They were initially characterised as inhibitors of lysosomal cysteine proteases, however, in recent years some alternative functions for cystatins have been proposed.
Magister, Špela, Kos, Janko
openaire   +2 more sources

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source