The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]
, 2015 We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa +10 more
core +2 more sources
Comparative analysis of cystatin superfamily in platyhelminths. [PDF]
PLoS ONE, 2015 The cystatin superfamily is comprised of cysteine proteinase inhibitors and encompasses at least 3 subfamilies: stefins, cystatins and kininogens. In this study, the platyhelminth cystatin superfamily was identified and grouped into stefin and cystatin ...
Aijiang Guo
doaj +1 more source
Serum Cystatin C for the diagnosis of acute Kidney Injury in Patients Admitted in the Emergency Department [PDF]
, 2015 BACKGROUND: Early diagnosis of acute kidney injury (AKI) at emergency department (ED) is a challenging issue. Current diagnostic criteria for AKI poorly recognize early renal dysfunction and may cause delayed diagnosis.
Bongiovanni, Cristina +7 more
core +4 more sources
Cystatin C is downregulated in prostate cancer and modulates invasion of prostate cancer cells via MAPK/Erk and androgen receptor pathways. [PDF]
PLoS ONE, 2009 Cystatin C is believed to prevent tumor progression by inhibiting the activities of a family of lysosomal cysteine proteases. However, little is known about the precise mechanism of cystatin C function in prostate cancer.
Barbara Wegiel +7 more
doaj +1 more source
Association Between APOL1 Genotypes and Risk of Cardiovascular Disease in MESA (Multi-Ethnic Study of Atherosclerosis). [PDF]
, 2017 BACKGROUND:APOL1 genetic variants confer an increased risk for kidney disease. Their associations with cardiovascular disease (CVD) are less certain. We aimed to compare the prevalence of subclinical CVD and incidence of atherosclerotic CVD and heart ...
Chen, Teresa K +8 more
core +1 more source
Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models
Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario +2 more
wiley +1 more source
Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats. [PDF]
PLoS ONE, 2017 Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins.
Danny Jensen +8 more
doaj +1 more source
The Comparison of Creatinine and Cystatin C Value in Preeclampsia Severity and Neonatal Outcome [PDF]
, 2016 Objectives: to compare the levels of creatinine and cystatin C with the severity of preeclampsia, and assess neonatal outcomes.Materials and Methods: Creatinine, cystatin C, and neonatal outcomes were assesed in 17 normotensive samples, 17 samples of ...
Wantania, J. (John) +1 more
core
Advanced Materials Interfaces, EarlyView.This review article explores applications in wearable sensors such as mechanical, electrophysiological, and gas sensors, highlighting advancements that improve device performance and predictability. In addition to analyzing graphene's synthesis techniques, including traditional and advanced laser‐based methods, the article discusses fabrication ...
Fatemeh Saeedi +2 more
wiley +1 more source
Serum Cystatin C Levels Are Associated With Obesity in Adolescents Aged 14–17 Years
Frontiers in Endocrinology, 2022 BackgroundThe association between serum cystatin C levels and obesity has not been fully explored in adolescents. This study aimed to explore the association between serum cystatin C levels and obesity in adolescents of different sexes.MethodsWe ...
Ying-Xiang Huo +7 more
doaj +1 more source