Results 61 to 70 of about 32,252 (169)

Population‐Based Prediction Equations for Appendicular Skeletal Muscle Mass: A Three‐Phase Validation Study in 13 582 Asian Adults

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Accurate estimation of appendicular skeletal muscle mass (ASM) is crucial for sarcopenia diagnosis, but device‐dependent approaches (dual‐energy X‐ray absorptiometry [DXA] or bioelectrical impedance analysis [BIA]) limit widespread application in community settings.
Hsi‐Yu Lai, Shu Zhang, I‐Tzu Chen, Rei Otsuka, Wei‐Ju Lee, Chih‐Kuang Liang, Ko‐Han Yen, Hidenori Arai, Fei‐Yuan Hsiao, Liang‐Kung Chen   +9 more
wiley   +1 more source

Appendicular Skeletal Muscle Mass and Sarcopenia as Prognostic Markers in Amyotrophic Lateral Sclerosis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Amyotrophic lateral sclerosis (ALS) is characterized by progressive muscle wasting and functional decline. Prognostic assessment in clinical practice relies largely on functional scales and traditional anthropometric measures. The prognostic relevance of muscle mass, muscle strength and sarcopenia in ALS remains incompletely defined.
María Teresa Zarco‐Martín, María Carmen Andreo‐López, Miriam Soraya Yagui‐Beltrán, María Luisa Fernández‐Soto   +3 more
wiley   +1 more source

Kidney Structure and Blood Flow Predict Function and Enable Image‐Based eGFR With Non‐Contrast MRI

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Multiparametric renal MRI in healthy adults identified cortical thickness (r² = 0.38) and renal blood flow (r² = 0.29; both p < 0.001) as the strongest predictors of creatinine‐based eGFR. Together, these measures explained 47% of eGFR variability. Prospective validation demonstrated low bias (−4.9 to 3.4 mL/min/1.73 m²) and good accuracy (p30: 87%–92%)
Emily Powell, Corina Margain, Jiachen Wang, Joel Adler, Alexandra Clark, Adam Bush   +5 more
wiley   +1 more source

On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur

Experimental Physiology, EarlyView.
Anders Møller Greve, Anna Agnes Lytzen, Hrefna Sæunn Einarsdóttir, Michael Perch, Ronan M. G. Berg   +4 more
wiley   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1110-1122, October 2026.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source

Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9054-9068, October 2026.
ABSTRACT Background Lifestyle interventions targeting metabolic health may influence chronic kidney disease (CKD) risk, particularly among adults with type 2 diabetes and obesity. We evaluated real‐world associations between a telehealth‐delivered, individualized nutrition therapy program (VINT) and CKD incidence and progression compared with usual ...
Shaminie J. Athinarayanan, Petter Bjornstad, Priya V. Shanmugam, Thomas Weimbs, Adam J. Wolfberg, Jeff S. Volek, Jonathan Himmelfarb, Richard J. Johnson   +7 more
wiley   +1 more source

Feasibility of Decentralised Response‐Guided Albuminuria Monitoring to Optimise Empagliflozin and Finerenone Therapy in Type 2 Diabetes and Chronic Kidney Disease

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9412-9422, October 2026.
ABSTRACT Aims To assess the feasibility of a decentralised response‐guided trial and to characterise urinary albumin‐to‐creatinine ratio (UACR) responses to empagliflozin and finerenone in type 2 diabetes and chronic kidney disease (CKD). Materials and Methods Adults with type 2 diabetes, estimated glomerular filtration rate (eGFR) ≥ 25 mL/min/1.73 m2,
Jelle M. Beernink, Gozewijn D. Laverman, Hiddo J. L. Heerspink   +2 more
wiley   +1 more source

A Multicenter, Open‐Label, Phase 2 Trial Comparing Crizanlizumab Combined With Standard Therapy to Standard Therapy Alone on Renal Function in Patients With Sickle Cell Nephropathy (STEADFAST)

American Journal of Hematology, Volume 101, Issue 10, Page 2666-2671, October 2026.
Kenneth I. Ataga, Pablo Bartolucci, Santosh L. Saraf, Vimal K. Derebail, Adlette Inati, Jeffrey D. Lebensburger, Laurie DeBonnett, Rodolfo D. Cancado, Claire C. Sharpe   +8 more
wiley   +1 more source

Combined sleep behaviors, mediating biomarkers, and incident vascular complications among individuals with type 2 diabetes: A prospective study in UK Biobank

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1782-1793, October 2026.
Among UK Biobank participants with type 2 diabetes, combined healthy sleep behaviors were associated with lower risks of vascular complications. Lipid and inflammatory biomarkers partially mediated these associations. ABSTRACT Aims To prospectively examine how combined sleep behaviors affect vascular complications in type 2 diabetes, whether these ...
Yanqiu Zou, Xia Jiang, Jinyu Zhou, Tao Han, Sirui Zheng, Mingshuang Tang, Yutong Wang, Lin Chen, Lingli Qiu, Xuan Wu, Zhixin Tan, Yunjie Liu, Bowen Lei, Xiaofeng Ma, Di Zhang, Jiaqiang Liao, Jiayuan Li, Ben Zhang, Mengyu Fan   +18 more
wiley   +1 more source

Disulfiram Attenuates Adenine‐Induced Renal Fibrosis by Modulating Inflammatory and Immunometabolic Responses

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Chronic kidney disease (CKD) is characterized by persistent inflammation that drives progressive renal injury and fibrosis. In this study, we demonstrate that disulfiram markedly attenuates kidney injury and fibrosis in adenine‐induced nephropathy by suppressing innate immune responses and reducing DNA damage and cellular senescence.
Saori Kin, Yuji Oe, Shun Ishigaki, Ichiro Fujio, Mariko Miyazaki, Tetsuhiro Tanaka   +5 more
wiley   +1 more source