Results 91 to 100 of about 19,945,001 (395)

Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients [PDF]

, 2005
INTRODUCTION: In critically ill patients sudden changes in glomerular filtration rate (GFR) are not instantly followed by parallel changes in serum creatinine.
Casasnovas, Pilar, Jiménez, Manuel, Manzanares, Jesus, Soriano, Maria-Cruz, Villa, Patricia   +4 more
core   +2 more sources

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

Advanced Science, EarlyView.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng, Ge Hu, Shenbo Zhang, Rui Lv, Limeng Sun, Zhe Zhang, Zhengyu Jin, Yanyan Wu, Chen Huang, Lu Ye, Yunlu Feng, Zhe‐Sheng Chen, Zhiwei Wang, Huadan Xue, Aiming Yang   +14 more
wiley   +1 more source

Cystatin C Level in Prediabetic and Diabetic Patients

Southern Clinics of Istanbul Eurasia, 2017
INTRODUCTION[|]Cystatin C is a novel marker of kidney function, considered to be more accurate than creatinine. Serum Cystatin C has been shown to correlate with the progression of pre-diabetes and type 2 diabetes mellitus.
Şafak Akın, Banu Pınar Şarer Yürekli, Neşe Ersöz Gülçelik, Jale Karakaya, Miyase Bayraktar, Aydan Usman   +5 more
doaj   +1 more source

Creatinine and cystatin C: what are the values? [PDF]

Kidney International, 2009
Recent studies indicate that serum cystatin C is a better marker of glomerular filtration rate (GFR) and is a stronger predictor of cardiovascular disease and mortality than serum creatinine. Before cystatin C can gain wide acceptance, information about factors that affect generation, elimination, and analysis is needed. Stevens et al.
openaire   +3 more sources

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu, Feng Zhang, Jingpu Wang, Jian Zhang, Chenguang Li, Yang Lyu, Yiwen Wang, Rong Huang, Yang Gao, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Junbo Ge   +13 more
wiley   +1 more source

Szlenk index of $C(K)\widehat{\otimes}_πC(L)$ [PDF]

arXiv, 2020
We compute the Szlenk index of an arbitrary projective tensor product $C(K)\widehat{\otimes}_\pi C(L)$ of spaces $C(K), C(L)$ of continuous functions on scattered, compact, Hausdorff spaces. In particular, we show that it is simply equal to the maximum of the Szlenk indices of the spaces $C(K), C(L)$. We deduce several results regarding non-isomorphism
arxiv  

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

Correlation of Serum Cystatin C with Glomerular Filtration Rate in Patients Receiving Platinum-Based Chemotherapy [PDF]

, 2016
Objectives. Serum cystatin C seems to be an accurate marker of glomerular filtration rate (GFR) compared to serum creatinine. The aim of this work was to explore the possibility of using serum cystatin C instead of serum creatinine to early predict renal
Barchiesi, Vittoria, Cantile, Monica, Cavalcanti, Ernesta, Cecere, Sabrina Chiara, Cerasuolo, Dionigio, Costanzo, Raffaele, Di Maio, Massimo, Di Paola, Flaviano, Morabito, Alessandro, Perrone, Francesco, Pignata, Sandro   +10 more
core   +2 more sources

Risk Factors and Predictive Models for Sarcopenia in Older Adults

AGING MEDICINE, EarlyView.
Independent risk factors for sarcopenia identified by Lasso regression and logistic regression in the study were BMI, prealbumin, albumin/globulin ratio (A/G ratio), serum creatinine, and phosphorus. These factors were used to construct a nomogram model and a decision tree model. Both models showed effectiveness in predicting sarcopenia in older adults,
Shiyuan Zhang, Xue Yang, Nina An, Meng Lv, Lanyu Yang, Rui Liu, Song Hu, Weiguo Chen, Wenjing Feng, Yongjun Mao   +9 more
wiley   +1 more source

Comparison of estimated glomerular filtration rate by the chronic kidney disease epidemiology collaboration (CKD-EPI) equations with and without Cystatin C for predicting clinical outcomes in elderly women. [PDF]

PLoS ONE, 2014
BACKGROUND: Reduced estimated glomerular filtration rate (eGFR) using the cystatin-C derived equations might be a better predictor of cardiovascular disease (CVD) mortality compared with the creatinine-derived equations, but this association remains ...
Wai H Lim, Joshua R Lewis, Germaine Wong, Robin M Turner, Ee M Lim, Peter L Thompson, Richard L Prince   +6 more
doaj   +1 more source