Results 91 to 100 of about 60,453 (247)
Beta-Trace Protein als endogener renaler Biomarker zur Bestimmung der Nierenfunktion bei Individuen im Alter von 70 Jahren und älter [PDF]
, 2019 Background The exact measurement of glomerular filtration rate (GFR) is important for diagnostics and therapy of patients with chronic kidney disease. The common used filtration markers creatinine and cystatin C show some disadvantages.
Koep, Camilla
core +1 more source
Cystatin C for Therapeutic Drug Monitoring
Clinical Chemistry, 2015 A 78-year-old man with prostate cancer needed intravenous treatment with amikacin for a suspected gram-negative bacillary respiratory infection. He had a body surface area of 1.97 m2, weight of 78 kg, and body mass index of 29 kg/m2. Laboratory test results are shown in Table 1. Because the initial renal function was judged to be normal and the patient
Noemí, Rebollo +1 more
openaire +2 more sources
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani +3 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Cystatins as calpain inhibitors: Engineered chicken cystatin- and stefin B-kininogen domain 2 hybrids support a cystatin-like mode of interaction with the catalytic subunit of μ-calpain [PDF]
, 2001 Within the cystatin superfamily, only kininogen domain 2 (KD2) is able to inhibit μ- and m-calpain. In an attempt to elucidate the structural requirements of cystatins for calpain inhibition, we constructed recombinant hybrids of human stefin B (an ...
Anastasi A. +14 more
core +1 more source
VIEW, EarlyView.We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani +12 more
wiley +1 more source
BMC Pulmonary MedicineObjective This study seeks to elucidate variances in cystatin C levels between patients with Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and controls while also assessing the impact of cystatin C on cardiovascular and cerebrovascular complications ...
Nianying Fu, Xiaotao Tan, Jie He
doaj +1 more source
Association of urinary uromodulin with kidney function decline and mortality: the health ABC study . [PDF]
, 2017 BackgroundUrine uromodulin (uUMOD) is a protein secreted by the kidney tubule. Recent studies have suggested that higher uUMOD may be associated with improved kidney and mortality outcomes.MethodsUsing a case-cohort design, we evaluated the association ...
Bennett, Michael R +11 more
core +1 more source
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source