Results 31 to 40 of about 38,749 (246)

Reduced cystatin C-estimated GFR and increased creatinine-estimated GFR in comparison with iohexol-estimated GFR in a hyperthyroid patient: A case report

Journal of Medical Case Reports, 2008
Introduction Estimation of the glomerular filtration rate (GFR) is essential for the evaluation of patients with kidney disease, and for treating patients with drugs that are eliminated from the circulation by the kidneys. Cystatin C has been shown to be
Karawajczyk Malgorzata, Ramklint Mia, Larsson Anders   +2 more
doaj   +1 more source

Expression and role of cystatin C in hyperthermia-induced brain injury in rats

Mathematical Biosciences and Engineering, 2023
Cystatin C, the full name of cystatin C, is one of the most potent cathepsin inhibitors currently known, which can strongly inhibit cathepsin in lysosomes and regulate the level of intracellular proteolysis. Cystatin C plays a very broad role in the body.
Haiqiang Liu, Feifei Shen, Hewei Zhang, Weikai Zhang   +3 more
doaj   +1 more source

Impact of cystatin C-derived glomerular filtration rate in patients undergoing transcatheter aortic valve implantation

Frontiers in Cardiovascular Medicine, 2023
BackgroundChronic kidney disease (CKD) impacts prognosis in patients undergoing transcatheter aortic valve implantation (TAVI). While estimated glomerular filtration rate (eGFR) calculated from serum creatinine [eGFR (creatinine)] is affected by body ...
Yusuke Kure, Tsukasa Okai, Yasuhiro Izumiya, Hisako Yoshida, Kazuki Mizutani, Tomohiro Yamaguchi, Mana Ogawa, Atsushi Shibata, Asahiro Ito, Yosuke Takahashi, Toshihiko Shibata, Daiju Fukuda   +11 more
doaj   +1 more source

Serum cystatin C measurement in differential diagnosis of intra and extrahepatic cholestatic diseases

Annals of Hepatology, 2010
Objective. Cystatin C is a very potent inhibitor of cysteine proteinases and, it has been clinically applied as a sensitive marker in monitoring of renal and liver functions.
Mehmet Buyukberber, Dr., Irfan Koruk, Oztekin Cýkman, Mehmet Koruk, Mehmet Emin Küçükoglu, Abdullah Sakman, Omer Demir, Saime Sahinoz   +7 more
doaj   +1 more source

Cystatin C and Subclinical Brain Infarction [PDF]

Journal of the American Society of Nephrology, 2005
Subclinical brain infarcts (SBI) are common in the elderly and are associated with covert neurologic and cognitive impairment. Although renal impairment is associated with accelerated cerebrovascular disease and an increased risk for clinically apparent brain infarct, few studies have examined the relationship between renal function and SBI, and these ...
Stephen L, Seliger, W T, Longstreth, Ronit, Katz, Teri, Manolio, Linda F, Fried, Michael, Shlipak, Catherine O, Stehman-Breen, Anne, Newman, Mark, Sarnak, Daniel L, Gillen, Anthony, Bleyer, David S, Siscovick   +11 more
openaire   +2 more sources

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Serum Cystatin C as a Biomarker in Diffuse Large B-Cell Lymphoma

Scientia Pharmaceutica, 2017
Elevated serum levels of cystatin C are found to be related to poor outcome and metastatic potential of some malignant disorders. To evaluate the clinical prominence of serum cystatin C in diffuse large B-cell lymphoma (DLBCL), blood samples were ...
Nada E. Hammouda, Manal A. Salah El-Din, Mamdouh M. El-Shishtawy, Amal M. El-Gayar   +3 more
doaj   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source