Results 31 to 40 of about 37,835 (197)

Cystatin C‐based eGFR better predicts renal vancomycin clearance than creatinine‐based eGFR in patients with allogeneic stem cell transplantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.
Eva‐Maria A. Wansing   +7 more
wiley   +1 more source

CLINICAL ANALYSIS OF ASSOCIATION OF CYSTATIN C AND ATRIAL FIBRILLATION

open access: yesРоссийский кардиологический журнал, 2014
Some studies have disclosed atrial fibrillation (AF) is associated with inflammation. Cystatin C is not only inflammatory markers but also an independent predictor of cardiovascular events.Aim.
Ping Liu, Shujian Sui, Dongling Xu
doaj   +3 more sources

Externally added cystatin C reduces growth of A375 melanoma cells by increasing cell cycle time

open access: yesFEBS Open Bio, 2021
Some secreted cysteine protease inhibitors of the cystatin family appear to affect intracellular proteolysis and growth of human cells, as a result of internalization. Here, we studied the effects of external addition of the most abundant human cystatin,
Hanna Wallin   +2 more
doaj   +1 more source

Biomarkers of Drug‐Induced Kidney Injury: Use in Clinical Trials and Recent Examples of Impact on Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This manuscript describes the scope of implementation and impact of a regulatory agency‐qualified panel of six urine biomarkers on drug development, the process for which was conducted and funded by the Critical Path Institute, the Foundation for the National Institutes of Health, and the United States Food and Drug Administration.
Tanja S. Zabka   +7 more
wiley   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera   +12 more
wiley   +1 more source

Cystatin C Level in Prediabetic and Diabetic Patients

open access: yesSouthern Clinics of Istanbul Eurasia, 2017
INTRODUCTION[|]Cystatin C is a novel marker of kidney function, considered to be more accurate than creatinine. Serum Cystatin C has been shown to correlate with the progression of pre-diabetes and type 2 diabetes mellitus.
Şafak Akın   +5 more
doaj   +1 more source

Haemodynamic consequences of acute pulmonary embolism predict risk of CTPA‐related acute kidney injury

open access: yesESC Heart Failure, EarlyView.
The graphical abstract summarizes that normotensive APE patients with elevated NT‐proBNP levels and higher BOVA scores are at increased risk of AKI and should be closely monitored for renal injury during hospitalization. Abstract Introduction Computed tomography pulmonary angiography (CTPA) is an important study in the diagnosis of acute pulmonary ...
Anna M. Imiela   +10 more
wiley   +1 more source

The transcriptional profile of iron deficiency in patients with heart failure: Heme‐sparing and reduced immune processes

open access: yesEuropean Journal of Heart Failure, EarlyView.
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg   +17 more
wiley   +1 more source

Correlation between Serum Ferritin, Serum Cystatin C, and Renal Function in Children with β Thalassemia Major

open access: yesMajalah Kedokteran Bandung, 2019
Renal dysfunction caused by iron overload is characterized by an increase in ferritin and cystatin C levels. The objective of this study was to determine the correlation between ferritin, cystatin C, and renal function in children with β thalassemia ...
Suci Saptyuni Permadi   +2 more
doaj   +1 more source

Comparison of estimated glomerular filtration rate by the chronic kidney disease epidemiology collaboration (CKD-EPI) equations with and without Cystatin C for predicting clinical outcomes in elderly women. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Reduced estimated glomerular filtration rate (eGFR) using the cystatin-C derived equations might be a better predictor of cardiovascular disease (CVD) mortality compared with the creatinine-derived equations, but this association remains ...
Wai H Lim   +6 more
doaj   +1 more source

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