Results 41 to 50 of about 38,749 (246)

CLINICAL ANALYSIS OF ASSOCIATION OF CYSTATIN C AND ATRIAL FIBRILLATION

Российский кардиологический журнал, 2014
Some studies have disclosed atrial fibrillation (AF) is associated with inflammation. Cystatin C is not only inflammatory markers but also an independent predictor of cardiovascular events.Aim.
Ping Liu, Shujian Sui, Dongling Xu
doaj   +3 more sources

Hiperurisemia dan Cystatin C

Jurnal Analis Medika Biosains (JAMBS), 2020
Hiperurisemia merupakan keadaan kadar asam meningkat dalam darah. Kadarnya yang meningkat dapat menyebabkan penyakit, salah satunya yaitu adalah gangguan ginjal. Parameter cystatin C dipakai sebagai parameter yang lebih unggul dibanding kreatinin dalam menilai fungsi ginjal.
Meri Meri, Yane Liswanti
openaire   +2 more sources

Cystatin C uptake in the eye [PDF]

Graefe's Archive for Clinical and Experimental Ophthalmology, 2004
As a secreted protein, cystatin C is assumed to play its role in the extracellular compartment, where it can inhibit virtually all cysteine proteases of families C1 (cathepsin B, L, S) and C13 (mammalian legumain-related proteases). Since many of its potential target enzymes in the eye reside in intracellular compartments, we sought evidence for a ...
Wassélius, Johan, Johansson, Kjell, Håkansson, Katarina, Abrahamson, Magnus, Ehinger, Berndt   +4 more
openaire   +2 more sources

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Externally added cystatin C reduces growth of A375 melanoma cells by increasing cell cycle time

FEBS Open Bio, 2021
Some secreted cysteine protease inhibitors of the cystatin family appear to affect intracellular proteolysis and growth of human cells, as a result of internalization. Here, we studied the effects of external addition of the most abundant human cystatin,
Hanna Wallin, Samar Hunaiti, Magnus Abrahamson   +2 more
doaj   +1 more source

Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease

Annals of Neurology, EarlyView.
Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins, Rory Boyle, Colleen Morse, Anurag Verma, Christopher A. Brown, Kyra S. O'Brien, Marina Serper, Nadia Dehghani, Penn Medicine BioBank, Corey T. McMillan, Edward B. Lee, Leslie M. Shaw, David A. Wolk   +12 more
wiley   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source

Comparison of estimated glomerular filtration rate by the chronic kidney disease epidemiology collaboration (CKD-EPI) equations with and without Cystatin C for predicting clinical outcomes in elderly women. [PDF]

PLoS ONE, 2014
BACKGROUND: Reduced estimated glomerular filtration rate (eGFR) using the cystatin-C derived equations might be a better predictor of cardiovascular disease (CVD) mortality compared with the creatinine-derived equations, but this association remains ...
Wai H Lim, Joshua R Lewis, Germaine Wong, Robin M Turner, Ee M Lim, Peter L Thompson, Richard L Prince   +6 more
doaj   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Correlation between Serum Ferritin, Serum Cystatin C, and Renal Function in Children with β Thalassemia Major

Majalah Kedokteran Bandung, 2019
Renal dysfunction caused by iron overload is characterized by an increase in ferritin and cystatin C levels. The objective of this study was to determine the correlation between ferritin, cystatin C, and renal function in children with β thalassemia ...
Suci Saptyuni Permadi, Lelani Renarti, Dedi Rachmadi   +2 more
doaj   +1 more source