Results 21 to 30 of about 468 (99)

Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication

open access: yesNeurobiology of Disease, 2020
A number of publications have reported that cysteamine has significant therapeutic effects on several aspects of Parkinson's disease (PD)-related pathology but none of these studies have evaluated its impact on pathological forms of α-Synuclein (α-Syn ...
Alberto Siddu   +7 more
doaj   +1 more source

Limitations and Challenges in the Stability of Cysteamine Eye Drop Compounded Formulations

open access: yesPharmaceuticals, 2021
Accumulation of cystine crystals in the cornea of patients suffering from cystinosis is considered pathognomonic and can lead to severe ocular complications.
Cristina Martín-Sabroso   +7 more
doaj   +1 more source

Evaluation of the effect of adding cysteamine on Ros 308 sperm quality parameters and reduction of lipid peroxidation rate during freezing-thawing process [PDF]

open access: yesپژوهش های علوم دامی, 2022
Introduction: Long-term storage of semen is essential for achieving the benefits of artificial insemination (Tuncer et al. 2010). This is carried out by sperm cryopreservation, which stops the sperm metabolic activities, allowing long storage (Bailey et ...
M Nazari , H Daghigh Kia and J Emami
doaj   +1 more source

A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan

open access: yesJournal of Chemistry, 2013
A carbon-paste electrode modified with ferrocenecarboxaldehyde and NiO nanoparticle (NiO/NPs) was used for the sensitive and selective voltammetric determination of cysteamine in the presence of tryptophan.
Hassan Karimi-Maleh   +4 more
doaj   +1 more source

Synthesis Of Some Novel Silver-Cysteamine Complexes

open access: yesMolecules, 2000
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and ...
Davood Nematollahi   +2 more
doaj   +1 more source

Cysteamine in Maturation Medium Enhances Nuclear Maturation and Fertilization Rate of Sheep Oocytes In Vitro

open access: yesHayati Journal of Biosciences, 2020
Low nuclear maturation and fertilization rate is one obstacle in the in vitro embryo production which decrease embryo yield. This problem is presumable related with high production of reactive oxygen species (ROS) during maturation process.
Feni Dwi Kartika Gulo   +2 more
doaj   +1 more source

THE EFFECTIVITY OF CYSTEAMINE SUPPLEMENTATION ON IMPROVING THE IN VITRO FERTILIZATION RATE OF SHEEP OOCYTES

open access: yesJurnal Kedokteran Hewan, 2021
The purpose of this study was to evaluate the effectiveness of cysteamine supplementation on the maturation medium and/or in vitro fertilization medium with regards to improving the normal fertilization rate of sheep oocytes, which are characterized by ...
Dona Astari Nurkarimah   +3 more
doaj   +1 more source

Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment. [PDF]

open access: yesPLoS ONE, 2011
OBJECTIVE: Stress and glucocorticoid hormones, which are released into the circulation following stressful experiences, have been shown to contribute significantly to the manifestation of anxiety-like behaviors observed in many neuropsychiatric disorders.
Ammar Kutiyanawalla   +2 more
doaj   +1 more source

Myeloperoxidase-oxidase oxidation of cysteamine [PDF]

open access: yesBiochemical Journal, 1988
Cysteamine oxidation was shown to be catalysed by nanomolar concentrations of myeloperoxidase in a peroxidase-oxidase reaction, i.e. an O2-consuming oxidation of a compound catalysed by peroxidase without H2O2 addition. When auto-oxidation of the thiol was prevented by the metal-ion chelator diethylenetriaminepenta-acetic acid, native, but not heat ...
B E Svensson, S Lindvall
openaire   +3 more sources

Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy

open access: yesCells, 2021
The ongoing pandemic of coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), needs better treatment options both at antiviral and anti-inflammatory levels.
Tonino Alonzi   +13 more
doaj   +1 more source

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