Results 11 to 20 of about 12,238 (214)

Synthesis Of Some Novel Silver-Cysteamine Complexes

open access: yesMolecules, 2000
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and ...
Davood Nematollahi   +2 more
doaj   +2 more sources

Cysteamine ophthalmic hydrogel for the treatment of ocular cystinosis [PDF]

open access: yesFarmacia Hospitalaria, 2017
Ocular cystinosis is a rare disease characterised by the deposit of cystine crystals on the corneal surface, which hinder patients’ eyesight. Oral cysteamine is given as cysteamine; however, it does not reach the cornea due to the lack of corneal ...
Anxo Fernández-Ferreiro   +9 more
doaj   +5 more sources

Cysteamine Toxicity in Patients with Cystinosis

open access: yesThe Journal of Pediatrics, 2011
To report new adverse effects of cysteamine.Detailed clinical information was obtained from the patients' physicians.New adverse events were reported in 8 of 550 patients with cystinosis treated with cysteamine in Europe during the last 5 years. Detailed clinical information was not available for 2 of these patients, 1 of whom died from cerebral ...
Besouw, M.T.   +14 more
openaire   +6 more sources

Cysteamine Inhibits Glycine Utilisation and Disrupts Virulence in Pseudomonas aeruginosa

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Pseudomonas aeruginosa is a major opportunistic human pathogen which employs a myriad of virulence factors. In people with cystic fibrosis (CF) P. aeruginosa frequently colonises the lungs and becomes a chronic infection that evolves to become less ...
Douglas J. Fraser-Pitt   +12 more
doaj   +2 more sources

SERS Spectral Bands of L-Cysteine, Cysteamine and Homocysteine fitted by Tsallis q-Gaussian functions [PDF]

open access: yes, 2023
Tsallis q-Gaussian functions are probability distributions possessing a shape which can be stretched from a Lorentzian to a Gaussian profile, according to the q-index parameter of their generalized exponentials.
Amelia Carolina, Sparavigna
core   +1 more source

The cytotoxic effect of cysteamine and its combinations with various endodontic intracanal medications on fibroblast cells: in vitro study

open access: yesBulletin of the National Research Centre, 2023
Background This study was established to assess cysteamine’s cytotoxic effect alone and in combination with various intracanal medications on fibroblast cells, because the biocompatibility of intracanal medication is considered one of the main factors ...
Esraa Adel Mohamed Abd Elhameed ElGammal   +3 more
doaj   +1 more source

Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient Mice

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background We have shown previously that low‐density lipoprotein (LDL) can be oxidized in the lysosomes of macrophages, that this oxidation can be inhibited by cysteamine, an antioxidant that accumulates in lysosomes, and that this drug decreases ...
Feroz Ahmad   +8 more
doaj   +1 more source

Mechanisms for the Cytotoxicity of Cysteamine [PDF]

open access: yesToxicological Sciences, 2001
The major aim of this study was to quantitatively assess the contribution of H2O2 generation to the cytotoxicity induced by cysteamine. Cysteamine produces H2O2 at levels that correlate with its toxicity between 23 and 160 microM. A maximum of 6.9 microM H2O2 is generated by 625 microM cysteamine.
T M, Jeitner, D A, Lawrence
openaire   +2 more sources

A new proof of evidence of cysteamine quantification for therapeutic drug monitoring in patients with cystinosis

open access: yesOrphanet Journal of Rare Diseases, 2022
Background To date, measurement of intracellular cystine is used for the therapeutic monitoring of patients affected by cystinosis in treatment with cysteamine.
Martina Franzin   +6 more
doaj   +1 more source

Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs

open access: yesAnimals, 2021
This study aimed to explore the effects of dietary coated cysteamine on oxidative stress and inflammation in diquat-induced weaning pigs. Twenty-four pigs were randomly assigned to three dietary groups with eight replicates: the control (fed base diet ...
Shanshan Wang   +8 more
doaj   +1 more source

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