Results 41 to 50 of about 10,629 (179)

Contrast Agents for Enhanced Bioimaging: A Comprehensive Review

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube, Donald Fernandes, Arthur Abinader Vasconcelos, Hugo de Campos Braga, Alan Kelbis Oliveira Lima, José Arnaldo Santana Costa, Karla Furtado Andriani, Ester da Cunha Meira Santos, Antonio Jorge Silva Araújo Junior, Hauster Maximiler Campos de Paula, Wallace Júnio Reis, Kashif Gul, Nida Wahab, Luis Carlos Resio, Elisa Kawana Leal dos Santos, Márcio Peres de Araujo, Matheus Allen P. da Silva, Juliana Paula da Silva   +17 more
wiley   +1 more source

Enteric-Coated Cysteamine Bitartrate in Cystinosis Patients

Cystinosis is a severe inherited metabolic storage disease caused by the lysosomal accumulation of cystine. Lifelong therapy with the drug cysteamine bitartrate is necessary. Cysteamine cleaves intralysosomal cystine, and thereafter, it can exit from the
Rauwolf, K.K. (Kerstin), Harms, E. (Erik), Reunert, J. (Janine), Stein, C. (Christina) van, Ottolenghi, C. (Chris), Grebe, J. (Jürgen), Klank, S. (Sabrina), Grüneberg, M. (Marianne), Marquardt, T. (Thorsten)   +8 more
core   +1 more source

Machine Learning‐Assisted Fabrication of 3D‐Printed Extracellular Matrix Models

ChemNanoMat, Volume 12, Issue 7, July 2026.
Mimicking the extracellular matrix (ECM) is challenging due to the complex composition, architecture, morphology, and mechanical properties of native tissues, which are key targets in tissue engineering. 3D printing enables the fabrication of ECM models with high spatial resolution exploiting hydrogels retaining essential viscoelastic and water ...
Maddalena Bracchi, Francesco Nicotra, Laura Russo   +2 more
wiley   +1 more source

Cysteamine prevents vascular leakage through inhibiting transglutaminase in diabetic retina

, 2017
Cysteamine (an aminothiol), which is derived from coenzyme A degradation and metabolized into taurine, has beneficial effects against cystinosis and neurodegenerative diseases; however, its role in diabetic complications is unknown.
Seok-Ho Hong, Yeon-Ju Lee, Kwon-Soo Ha, Se-Hui Jung, Sohee Jeon, Won Sun Park, Young-Myeong Kim, JongYun Hwang, Eun-Taek Han   +8 more
core   +1 more source

Structural and Chemical Engineering of Sub‐Nanochannel Membranes Toward Ion Selectivity

Advanced Functional Materials, Volume 36, Issue 46, 8 June 2026.
This review summarizes recent advances in structural and chemical engineering of sub‐nanochannels for ion selectivity. We first introduce fundamental ion transport mechanisms within sub‐nanochannels, followed by strategies to tune pore size, geometry, and surface functionalities, categorized into charge‐based, ion‐recognition, hydrophilic bonding, and ...
Yuyu Su, Huacheng Zhang, Tamar L. Greaves, Qi Han, Weiwei Lei, Dan Liu   +5 more
wiley   +1 more source

Formulation study of cysteamine microparticulate systems

, 2020
Cysteamine is clinically used for the treatment of nephropathic cystinosis and is orally administered as cysteamine bitartrate. The daily dose of cysteamine (Cystagon®) for treatment of cystinosis in paediatric patients is 50 mg/kg per day, shared in ...
Adorni, Greta
core  

Engineering Pendant Group Chemistry to Control Hydrophilicity and Oxidative Degradation of Thioketal‐Based Biomaterials

Advanced Functional Materials, Volume 36, Issue 51, 25 June 2026.
Thioketal (TK) polymers are promising biomaterials due to their selective biodegradation by reactive oxygen species (ROS), but they respond slowly to physiologic doses of ROS. Here, the TK bond's pendant groups are modified to enhance the degradation of TK‐based implants both in vitro and in vivo.
Karina A. Bruce, Dylan W. Marques, Alan J. Fullenkamp, Emma‐Louise Lowell, Rais B. Fataki, Jake D. Ryan, John R. Martin   +6 more
wiley   +1 more source

Cysteamine-colon and cysteamine-duodenum lesions in rats. Attenuation by gastric pentadecapeptide BPC 157, cimetidine, ranitidine, atropine, omeprazole, sulphasalazine and methylprednisolone

, 2001
Recently, we showed cysteamine-duodenal lesions without gastric acid, since they were induced also in gastrectomized rats, as in naive rats, and they were inhibited by the novel stomach pentadecapeptide BPC 157 as well as standard antiulcer drugs (i.e ...
Sven Seiwerth, Darko Mikus, Tihomil Ziger, Darko Perovic, Dinko Stancic Rokotov, Zoran Simec, Ingrid Prkacin, Branko Turkovic, Stjepan Mise, Ivan Balen, Tomislav Anic, Jadranka Separovic, Josip Aralica, Martina Lovric Bencic, Predrag Sikiric, Bozidar Sebecic, Marijan Petek, Gorana Aralica, Ivo Sjekavica, Ljiljana Komericki, Zeljko Grabarevic, Mario Staresinic, Rudolf Rucman, Alenka Boban Blagaic, Zoran Ivasovic, SKROZA, Nevena, Miroslav Gjurasin, Ivo Rotkvic   +27 more
core   +1 more source

Copper deficiency in patients with cystinosis with cysteamine toxicity

, 2013
Item does not contain fulltextOBJECTIVES: To assess whether copper deficiency plays a role in the recently described cysteamine toxicity in patients with cystinosis, and to examine whether polymorphisms in copper transporters, lysyl oxidase, and/or type ...
Lillen, Marc R, Heuvel, L.P.W.J. van den, Malfait, Fransiska, Lilien, M.R., Besouw, Martine T, De Paepe, Anne, Lilien, Marc R., Emma, Francesco, van den Heuvel, Lambertus P., Symoens, Sofie, Janssen, Mirian C., Janssen, M.C.H., Nobili, F., Emma, F., Skovby, Flemming, Besouw, Martine T P, Greco, Marcella, Desmet, K., Symoens, S., Janssen, Mirian C, Schneider, Jerry, Schneider, J., Besouw, M.T., Lilien, Marc R, Greco, M., Malfait, F., Cornelissen, Elisabeth A, Levtchenko, Elena N, Paepe, A. de, Skovby, F., van den Heuvel, Lambertus P, Levtchenko, E.N., Nobili, François, Cornelissen, Elisabeth A., Desmet, Koen, Besouw, Martine T. P., Cornelissen, E.A.M., Levtchenko, Elena N.   +37 more
core   +1 more source

Cystamine and Cysteamine As Inhibitors of Transglutaminases In Vivo

, 2018
Cystamine is commonly used as a transglutaminase inhibitor. This disulfide undergoes reduction in vivo to the aminothiol compound, cysteamine. Thus, the mechanism by which cystamine inhibits transglutaminase activity in vivo could be due to either ...
Jeitner, Thomas M, Cooper, Arthur J. L., Pinto, John T.   +2 more
core   +2 more sources