Results 41 to 50 of about 18,063 (229)

Cysteamine in Maturation Medium Enhances Nuclear Maturation and Fertilization Rate of Sheep Oocytes In Vitro

Hayati Journal of Biosciences, 2020
Low nuclear maturation and fertilization rate is one obstacle in the in vitro embryo production which decrease embryo yield. This problem is presumable related with high production of reactive oxygen species (ROS) during maturation process.
Feni Dwi Kartika Gulo, Ni Wayan Kurniani Karja, Mohamad Agus Setiadi   +2 more
doaj   +1 more source

THE EFFECTIVITY OF CYSTEAMINE SUPPLEMENTATION ON IMPROVING THE IN VITRO FERTILIZATION RATE OF SHEEP OOCYTES

Jurnal Kedokteran Hewan, 2021
The purpose of this study was to evaluate the effectiveness of cysteamine supplementation on the maturation medium and/or in vitro fertilization medium with regards to improving the normal fertilization rate of sheep oocytes, which are characterized by ...
Dona Astari Nurkarimah, Ekayanti Mulyawati Kaiin, Ni Wayan Kurniani Karja, Mohamad Agus Setiadi   +3 more
doaj   +1 more source

Lysosomal oxidation of LDL alters lysosomal pH, induces senescence and increases secretion of pro-inflammatory cytokines in human macrophages [PDF]

, 2019
Objective We have shown that aggregated low density lipoproteins (LDL) is internalised by macrophages and oxidised in lysosomes by redox-active iron.
Ahmad, Feroz, Leake, David S.
core   +1 more source

Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy

Cells, 2021
The ongoing pandemic of coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), needs better treatment options both at antiviral and anti-inflammatory levels.
Tonino Alonzi, Alessandra Aiello, Linda Petrone, Saeid Najafi Fard, Manuela D’Eletto, Laura Falasca, Roberta Nardacci, Federica Rossin, Giovanni Delogu, Concetta Castilletti, Maria Rosaria Capobianchi, Giuseppe Ippolito, Mauro Piacentini, Delia Goletti   +13 more
doaj   +1 more source

Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment. [PDF]

PLoS ONE, 2011
OBJECTIVE: Stress and glucocorticoid hormones, which are released into the circulation following stressful experiences, have been shown to contribute significantly to the manifestation of anxiety-like behaviors observed in many neuropsychiatric disorders.
Ammar Kutiyanawalla, Alvin V Terry, Anilkumar Pillai   +2 more
doaj   +1 more source

Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed [PDF]

, 2018
Oxidised low density lipoprotein (LDL) was considered to be important in the pathogenesis of atherosclerosis, but the large clinical trials of antioxidants, including the first one using probucol (the PQRST Trial), failed to show benefit and have cast ...
Bard, Bedwell, Brodin-Sartorius, Cardey, Carew, Collins, Dabbagh, David S. Leake, De Grey, Dubinina, el-Saadani, Esterbauer, Esterbauer, Esterbauer, Feroz Ahmad, Frei, Giessauf, Giessauf, Güngör, Halliwell, Jackson, Kritharides, Kurz, Lee, Linschitz, Lund-Katz, Lynch, Meguro, Minotti, Mitchinson, Mitchinson, Morgan, Parthasarathy, Patterson, Pieroni, Ronsein, Satchell, Sempos, Sparrow, Steinberg, Steinberg, Sullivan, Tachiev, Takahashi, Tardif, Terman, Walldius, Walters, Wen, Wen, Wilkins, Yamashita, You, Yuan   +53 more
core   +1 more source

Gold Nanoparticle-Quantum Dot Fluorescent Nanohybrid:Application for Localized Surface Plasmon Resonance-induced Molecular Beacon Ultrasensitive DNA Detection [PDF]

, 2016
textversion ...
AM Alkilany, AV Delgado, B Sarmento, C-S Wu, D Giljohann, E Arkan, E Boisselier, EC Dreaden, Enoch Y. Park, EW Nägele, FA Aldaye, H Thakkar, J Homola, J Lyklema, JW Liu, JW Slot, L Qi, L Tong, M Lundqvist, O Adegoke, O Adegoke, Oluwasesan Adegoke, P Rademeyer, Q Guo, R Tantra, R Weissleder, RA Sperling, S Bhattacharjee, S Patila, T Hagigit, TB Huff, V Uskoković, VR Patel, W Haiss, X Montet, Y Wang, YQ Li   +36 more
core   +2 more sources

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

The effects of cysteamine on in vitro production of embryos from rare breed hanwoo (albino White and Black) ovum pick-up and slaughterhouse derived oocytes

Journal of Animal Reproduction and Biotechnology, 2016
Historically, Korea old cattle had been consisted with various lines of coat color brindle, black and white-brown breeds or more. The two rare lines of black and white coat color are maintained for animal resources and preserved critically.
Sung Woo Kim, Min Su Kim, Chan-Lan Kim, Dongkyo Kim, Namtae Kim, Hwan-Hoo Seong   +5 more
doaj   +1 more source

Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]

, 2018
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo, Brown, Lauren E., Cencic, Regina, Crandall, Ian, Gros, Philippe, Kain, Kevin C., Kennedy, James M., Langlais, David, Moradin, Neda, Pelletier, Jerry, Porco, John A., Schmeing, Martin, Tarry, Michael J.   +12 more
core   +1 more source