Results 51 to 60 of about 12,238 (214)
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
Medicinal Research Reviews, EarlyView.ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source
Spectroscopic Investigation of Cysteamine Dioxygenase
Biochemistry, 2020 Thiol dioxygenases are mononuclear non-heme FeII-dependent metalloenzymes that initiate the oxidative catabolism of thiol-containing substrates to their respective sulfinates. Cysteine dioxygenase (CDO), the best characterized mammalian thiol dioxygenase, contains a three-histidine (3-His) coordination environment rather than the 2-His-1-carboxylate ...
Rebeca L. Fernandez +4 more
openaire +3 more sources
Metabolic interactions between cysteamine and epigallocatechin gallate
, 2017 Phase II clinical trials indicate that the combination of cysteamine plus epigallocatechin gallate (EGCG) is effective against cystic fibrosis in patients bearing the most frequent etiological mutation (CFTRΔF508).
RAIA, VALERIA +25 more
core +1 more source
Cysteamine exerts in vitro antiviral activity against the SARS-CoV-2 Delta and Omicron variants
Cell Death Discovery, 2022 The novel SARS-CoV-2 variants of concern (VOC) represent a considerable global alarm because their mutations are known to affect transmissibility and cause immune escape.
Tonino Alonzi +9 more
doaj +1 more source
Pharmaceuticals, 2023 We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric +24 more
doaj +1 more source
Responsive Materials, EarlyView.Guided by the spectral demand of plant photosystems, this review summarizes the synthesis, emission regulation, dual‐emission design, and gram‐scale production of CDs for agricultural applications. Spectrally matched blue‐ and red‐emissive CDs enhance plant light utilization by converting underutilized light into photosynthetically active radiation and
Yijing Chen +5 more
wiley +1 more source
Simple Synthesis Method and Characterizations of Aggregation-Free Cysteamine Capped PbS Quantum Dot
Applied Sciences, 2019 Quantum dots have diverse chemical properties with different ligands attached on the surface. The cysteamine has been used as a ligand for various quantum dots because it has high solubility in water, and it facilitates binding of quantum dot and gold ...
Daekyung Kang +4 more
doaj +1 more source
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Small, EarlyView.Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
Increased human dermal microvascular endothelial cell survival induced by cysteamine
, 2013 Contains fulltext : 125972.pdf (Publisher’s version ) (Open Access)BACKGROUND: Cystinosis is an autosomal recessive disease caused by intralysosomal cystine accumulation, treated with cysteamine.
I. Bongaers +17 more
core +1 more source
Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez +5 more
wiley +2 more sources