Cysteamine activation of ELIC.
Outside-out patch-clamp recordings from HEK-293T cells expressing ELIC. ELIC currents evoked by alternating pulses of 30 mM and 10 mM or 50 mM cysteamine (black bar) are overlaid.
Borna Ghosh (486869) +2 more
core +1 more source
Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira +13 more
wiley +1 more source
Natural Aging of Biomaterials in Ambient and Physiological Environments
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley +1 more source
Cysteamine: an old drug with new potential
Item does not contain fulltextCysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low.
Levtchenko, Elena +7 more
core +1 more source
Synthesis Of Some Novel Silver-Cysteamine Complexes
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and ...
Davood Habibi +2 more
core +1 more source
Cysteamine ophthalmic hydrogel for the treatment of ocular cystinosis [PDF]
Ocular cystinosis is a rare disease characterised by the deposit of cystine crystals on the corneal surface, which hinder patients’ eyesight. Oral cysteamine is given as cysteamine; however, it does not reach the cornea due to the lack of corneal ...
Francisco Javier Otero-Espinar +19 more
core +1 more source
Cysteamine functionalised reduced graphene oxide modification of maleated poly(propylene) [PDF]
Graphene oxide (GO) was reduced (rGO) and then functionalised with an amino terminated thiol molecule (cysteamine) via a thiol-ene click chemistry reaction to produce reduced graphene oxide-cysteamine (rGO-cyst). The presence of the C–S bond in the X-ray
Abbas, Syeda +4 more
core +1 more source
Metabolic interactions between cysteamine and epigallocatechin gallate
Phase II clinical trials indicate that the combination of cysteamine plus epigallocatechin gallate (EGCG) is effective against cystic fibrosis in patients bearing the most frequent etiological mutation (CFTRΔF508).
RAIA, VALERIA +25 more
core +1 more source
Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate [PDF]
Halitosis due to dimethylsulfide (DMS) generation is a major side effect of cysteamine in the treatment of cystinosis. Recently, an enteric coated formulation of cysteamine bitartrate (RP103) administered twice daily was demonstrated to be non-inferior ...
Levtchenko, Elena +4 more
core +1 more source
Cysteamine inhibits glycine utilisation and disrupts virulence in pseudomonas aeruginosa.
Pseudomonas aeruginosa is a major opportunistic human pathogen which employs a myriad of virulence factors. In people with cystic fibrosis (CF) P. aeruginosa frequently colonises the lungs and becomes a chronic infection that evolves to become less ...
Fraser-Pitt, Douglas J. +25 more
core +3 more sources

