Limitations and Challenges in the Stability of Cysteamine Eye Drop Compounded Formulations
Accumulation of cystine crystals in the cornea of patients suffering from cystinosis is considered pathognomonic and can lead to severe ocular complications.
Cristina Martín-Sabroso+7 more
doaj +1 more source
Evaluation of the effect of adding cysteamine on Ros 308 sperm quality parameters and reduction of lipid peroxidation rate during freezing-thawing process [PDF]
Introduction: Long-term storage of semen is essential for achieving the benefits of artificial insemination (Tuncer et al. 2010). This is carried out by sperm cryopreservation, which stops the sperm metabolic activities, allowing long storage (Bailey et ...
M Nazari , H Daghigh Kia and J Emami
doaj +1 more source
Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2‐Adrenoceptor
A structure‐based design of a covalent photoswitchable ligand for the β2‐adrenergic receptor, a therapeutically relevant GPCR, is described. This tool facilitates the modification of the intrinsic activity of the protein by light. Computational analysis of its mechanism of action suggests that the photoswitch takes place within the binding pocket ...
Ulrike Wirth+9 more
wiley +2 more sources
The purpose of this study was to evaluate the effectiveness of cysteamine supplementation on the maturation medium and/or in vitro fertilization medium with regards to improving the normal fertilization rate of sheep oocytes, which are characterized by ...
Dona Astari Nurkarimah+3 more
doaj +1 more source
Supramolecular Chalcogen‐Bonded Shape Memory Actuators
Supramolecular chalcogen‐bonded liquid crystal elastomers incorporating Se⋯N interactions exhibit distinct shape memory and actuation properties. Stronger Se⋯N ChBs enable programmable one‐way and two‐way SME, while weaker S⋯N ChBs fail to induce actuation.
Hongshuang Guo+5 more
wiley +2 more sources
Synthesis Of Some Novel Silver-Cysteamine Complexes
The aim of this research was to synthesize some new silver-cysteamine complexes of potential biological interest. Reactions were carried out between silver nitrate and cysteamine (2-aminoethanethiol hydrochloride) under different conditions of pH and ...
Davood Nematollahi+2 more
doaj +1 more source
Superresolution Microscopy of the Volume Phase Transition of pNIPAM Microgels [PDF]
Hierarchical polymer structures such as pNIPAM microgels have been extensively studied for their ability to undergo significant structural and physical transformations that can be controlled by external stimuli such as temperature, pH or solvent ...
Braibanti, Marco+4 more
core +2 more sources
Cysteamine attenuates the decreases in TrkB protein levels and the anxiety/depression-like behaviors in mice induced by corticosterone treatment. [PDF]
OBJECTIVE: Stress and glucocorticoid hormones, which are released into the circulation following stressful experiences, have been shown to contribute significantly to the manifestation of anxiety-like behaviors observed in many neuropsychiatric disorders.
Ammar Kutiyanawalla+2 more
doaj +1 more source
Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate [PDF]
Halitosis due to dimethylsulfide (DMS) generation is a major side effect of cysteamine in the treatment of cystinosis. Recently, an enteric coated formulation of cysteamine bitartrate (RP103) administered twice daily was demonstrated to be non-inferior ...
Besouw, Martine+4 more
core +1 more source
Controlled Synthesis of Silver Nanoparticles Using Double Reductants and Its Voltammetric Characteristics Study [PDF]
Constructing robust silver nanoparticles (AgNPs) with good shape and dispersibility is of particular interest in analytical applications. Herein, monodispersibility AgNPs with the average size of 20 nm have been successfully prepared via one-pot method ...
Duan, Yubo, Jiang, Xiaochun, Xu, Zhihua
core +2 more sources