Results 51 to 60 of about 20,732 (256)

Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice [PDF]

, 2019
Background and aims: We have shown previously that low density lipoprotein (LDL) aggregated by vortexing is internalised by macrophages and oxidised by iron in lysosomes to form the advanced lipid/protein oxidation product ceroid.
Ahmad, Ahmad, Bachmanov, Baglione, Berliner, Besouw M, Bouazza, Dabbagh, David S. Leake, Devlin, Dohil, Dohil, El-Saadani, Esterbauer, Feroz Ahmad, Firth, Garner, Gerry, Goldstein, Heinemann, Javed, Jezegou, Jürgens, Kalatzis, Karunakaran, Khoo, Kritharides, Kuo, Leake, Lee, Liu, Marathe, Min-Oo, Mitchinson, Negre-Salvayre, Ojo, Omran, Oorni, Paigen, Palinski, Peter D. Weinberg, Pisoni, Portman, Quinn, Rajavashisth, Ruuth, Satchell, Schissel, Singh, Singh, Siow, Sneck, Steinberg, Steinberg, Tangirala, Tennezé, Tricon, Tsimikas, Ueda, Walters, Walters, Wen, Wilkins, Williams, Williams, Xu, Yichuan Wen, Yin, Yin, Yu, Yuan, Zahra Mohri, Zhang, Öörni   +73 more
core   +1 more source

Strong Plasmon–Exciton Coupling Tuned by Corner Etching of Gold Nanocubes and Nanotriangles

Advanced Optical Materials, EarlyView.
Systematic etching of gold nanocubes (AuNCs) and nanotriangles (AuNTs) reveals how nanoparticle morphology governs plasmon–exciton strong coupling. While rounding the corners of AuNCs weakens their coupling, triangular geometries robustly preserve deep strong coupling.
Jiyeon Lee, Seoyoung Hwang, Yoon‐Min Lee, Jeong‐Eun Park, Sangwoon Yoon   +4 more
wiley   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Daunorubicin and gambogic acid co-loaded cysteamine-CdTe quantum dots minimizing the multidrug resistance of lymphoma in vitro and in vivo [PDF]

, 2016
To minimize the side effects and the multidrug resistance (MDR) arising from daunorubicin (DNR) treatment of malignant lymphoma, a chemotherapy formulation of cysteamine-modified cadmium tellurium (Cys-CdTe) quantum dots coloaded with DNR and gambogic ...
Chen, Bing, Hu, Yong, Sun, Dan, Wang, Ruju, Xu, Peipei, Zhou, Yi   +5 more
core   +2 more sources

Low density lipoprotein oxidation by ferritin at lysosomal pH [PDF]

, 2018
Oxidation of low density lipoprotein (LDL) has been proposed to be involved in the pathogenesis of atherosclerosis. We have previously shown that LDL can be oxidised by iron in lysosomes.
Leake, David S., Ojo, Oluwatosin O.
core   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Trinuclear Heptamethine Dyes for Shortwave Infrared In Vivo Imaging

Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.
The reactivity of cyclopentenyl‐bridged polymethine dyes is leveraged to synthesize shortwave infrared (SWIR)‐emissive di‐ and trinuclear polymethine dyes. Chromenylium‐ and flavylium‐based trinuclear dyes demonstrate increased nucleophilic stability, minimal aggregation in micelle formulations, and notable lymph node accumulation.
Cesar A. Garcia, Eric Y. Lin, Emily B. Mobley, Allen Louie, Kaitlin M. Hartung, Jesus A. Araujo, Ellen M. Sletten   +6 more
wiley   +2 more sources

Characterisation and functionalisation of mechanically fractured graphene nanoribbons : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nanoscience at Massey University, Manawatū, New Zealand [PDF]

, 2017
Graphene has been heralded as the supermaterial of the future, boasting incredibly high electron mobility, thermal conductivity, and physical strength – all contained within the world’s first true 2D material, only a single atom thick.
Brooke, Samuel James
core  

Peptide Receptor‐Functionalized AuNP‐Embedded Zwitterionic Biopolymeric Nanohydrogel for Electrochemical Sclerostin Sensing

Advanced Science, EarlyView.
We report an electrochemical biosensor that employs biopanning‐derived affinity peptides as selective receptors on a multifunctional chitosan–zwitterionic–gold nanoparticle (CS–ZI–AuNPs) nanohydrogel interface. The CS–ZI–AuNPs nanohydrogel exhibits antifouling properties, abundant sites for stable peptide immobilization, and efficient electrochemical ...
Hyo Jeong Yang, Jae Hwan Shin, Mingi Jo, Changyeon Lee, Hyunmin Yi, Al‐Montaser Bellah H. Ali, Jong Pil Park   +6 more
wiley   +1 more source

The specificity of cysteamine oxygenase

FEBS Letters, 1975
Oxidation of cysteamine to hypotaurine is catalyzed by cysteamine oxygenase (EC 1.13.11.19), a non-heme iron enzyme of large distribution [l-3] . A similar oxidation of cysteine to cysteine sulfinic acid has been reported to require a different oxygenase [4,.5]. Specificity of cysteamine oxygenase has been studied earlier in this laboratory by assaying
Cavallini, D., Federici, G., Ricci, G., Duprè, S., Antonucci, A., De Marco, C.   +5 more
openaire   +2 more sources