Results 61 to 70 of about 20,516 (271)

Evaluation of NACA and diNACA in human cystinosis fibroblast cell cultures as potential treatments for cystinosis

Orphanet Journal of Rare Diseases, 2022
Background Cystinosis is a rare autosomal recessive lysosomal storage disease, associated with high morbidity and mortality. Mutations in the CTNS gene disable a membrane protein responsible for the transport of cystine out of the lysosome.
Emma Hector, Donald Cairns, G. Michael Wall   +2 more
doaj   +1 more source

Efficacy and safety of cysteamine-isobionicamide complex in postinflammatory hyperpigmentation: A 16-week, randomized, double-blinded, vehicle-controlled trial

Dermatologica Sinica, 2023
Background: Postinflammatory hyperpigmentation (PIH) is a prevalent acquired hyperpigmentation disorder with significant psychosocial implications. Cysteamine has demonstrated notable efficacy and safety in treating hyperpigmentation disorders.
Rosalie Tzu-Li Liu, Tsung-Fu Tsai, Yi-Jing Lai, Chau Yee Ng   +3 more
doaj   +1 more source

A novel approach to enhancing cellular glutathione levels [PDF]

, 2008
20 pages, 9 figures, 1 table.-- PMID: 18702664 [PubMed].-- PMCID: PMC2644427.-- NIHMSID: NIHMS90383.-- Printed version published Nov 2008.Glutathione (GSH) and GSH-associated metabolism provide the major line of defense for the protection of cells from ...
Lewerenz, Jan, Lozano, Carles, Maher, Pamela, Torres, Josep Lluís   +3 more
core   +1 more source

Zwitterionic Fluoropolymer‐Engineered Synaptic Clefts Enhance Ion Dynamics in Neuromorphic OECTs

Advanced Materials Technologies, EarlyView.
Polyzwitterionic DPVDF (DPVDF‐SZ) ion gels enhance neuromorphic OECT performance due to their reduced crystallinity compared to conventional fluoropolymer (e.g., PVDF‐HFP). These ion gels enable high transconductance, stable ion diffusion, and synaptic plasticity, including long‐term memory. Reservoir computing validation highlights their potential for
Ji Seon Kim, Young Je Kwon, Jung‐Hye Song, Yoon Ah Im, Dong Jun Han, Ho Jin Jung, Kie Yong Cho, Eun Kwang Lee   +7 more
wiley   +1 more source

From Selye’s and Szabo’s Cysteamine-Duodenal Ulcer in Rats to Dopamine in the Stomach: Therapy Significance and Possibilities

Pharmaceuticals, 2023
We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric, Alenka Boban Blagaic, Ivan Krezic, Helena Zizek, Luka Kalogjera, Ivan Maria Smoday, Vlasta Vukovic, Katarina Oroz, Helen Marie Chiddenton, Sara Buric, Marko Antunovic, Slaven Gojkovic, Sanja Strbe, Milena Skocic, Suncana Sikiric, Marija Milavic, Lidija Beketic Oreskovic, Antonio Kokot, Antun Koprivanac, Ivan Dobric, Marko Sever, Mario Staresinic, Lovorka Batelja Vuletic, Anita Skrtic, Sven Seiwerth   +24 more
doaj   +1 more source

Cysteamine: Clinical efficacy, safety and tolerability versus best-in-class treatments for melasma [PDF]

, 2021
Seemal R. Desai
openalex   +1 more source

Ionic Density‐Controlled Conjugated Polyelectrolytes for Interface Engineering in Inverted Colloidal PbS Quantum‐Dots Infrared Photodetector

Advanced Optical Materials, EarlyView.
This study demonstrates that conjugated polyelectrolytes with tunable ionic density can act as effective interfacial layers in inverted PbS quantum dot photodiodes. By enhancing dipole orientation and defect passivation at the ITO/QD interface, the devices exhibit suppressed dark current, improved photocurrent, and a record near‐infrared detectivity of
Chanwoo Lim, Jung Min Ha, Nayoung Kim, Byung Joon Moon, Byoung‐Soo Yu, Do Kyung Hwang, Woong Kim, Han Young Woo, Hyeonggeun Yu   +8 more
wiley   +1 more source

Immunomodulatory effects of cysteamine and its potential use as a host-directed therapy for tuberculosis

Frontiers in Immunology
ObjectiveCysteamine, a drug approved to treat cystinosis, has been proposed as a host-directed therapy for M. tuberculosis (Mtb) and SARS-CoV-2. The impact of cysteamine on the immune responses has not been fully investigated.
Saeid Najafi-Fard, Chiara Farroni, Linda Petrone, Anna Maria Gerarda Altera, Andrea Salmi, Valentina Vanini, Valentina Vanini, Gilda Cuzzi, Tonino Alonzi, Emanuele Nicastri, Gina Gualano, Fabrizio Palmieri, Mauro Piacentini, Mauro Piacentini, Delia Goletti   +14 more
doaj   +1 more source

Daunorubicin and gambogic acid co-loaded cysteamine-CdTe quantum dots minimizing the multidrug resistance of lymphoma in vitro and in vivo [PDF]

, 2016
To minimize the side effects and the multidrug resistance (MDR) arising from daunorubicin (DNR) treatment of malignant lymphoma, a chemotherapy formulation of cysteamine-modified cadmium tellurium (Cys-CdTe) quantum dots coloaded with DNR and gambogic ...
Chen, Bing, Hu, Yong, Sun, Dan, Wang, Ruju, Xu, Peipei, Zhou, Yi   +5 more
core   +2 more sources

Dual‐Laser Optical Tweezers for Photothermal Analysis of Hybrid Microgels

Advanced Science, EarlyView.
Dual‐laser optical tweezers unlock real‐time, single‐particle resolution of light‐driven actuation. Direct visualization and precise quantification of size changes under varying laser intensity provide new insights, overcoming limitations of conventional microscale actuator analysis.
Se‐Hyeong Jung, Chi Zhang, Nick Stauffer, Frank Scheffold, Lucio Isa   +4 more
wiley   +1 more source