Results 71 to 80 of about 25,803 (305)

Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic

open access: yesAdvanced Sensor Research, EarlyView.
This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin   +2 more
wiley   +1 more source

A Tailored Artificial Biocatalyst for Bacterial Endophthalmitis Therapy via Enhanced Ferroptosis‐Like Death

open access: yesAdvanced Science, EarlyView.
A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun   +9 more
wiley   +1 more source

Characterisation and functionalisation of mechanically fractured graphene nanoribbons : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nanoscience at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2017
Graphene has been heralded as the supermaterial of the future, boasting incredibly high electron mobility, thermal conductivity, and physical strength – all contained within the world’s first true 2D material, only a single atom thick.
Brooke, Samuel James
core  

A straightforward metal-free synthesis of 2-substituted thiazolines in air [PDF]

open access: yes, 2015
The authors are grateful to the Royal Society (University Research Fellowship to CSJC) for financial support.A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free ...
Cazin, Catherine S.J.   +3 more
core   +1 more source

Development of cysteamine loaded liposomes in liquid and dried forms for improvement of cysteamine stability

open access: yesInternational Journal of Pharmaceutics, 2020
Despite the high aqueous solubility of cysteamine, its unpleasant organoleptic properties, hygroscopicity, instability in solutions, and poor pharmacokinetic profile are the main drawbacks that limit its use for medical and cosmetic purposes. In this study, cysteamine-loaded liposomes were prepared using the ethanol injection method.
Catherine Charcosset   +2 more
openaire   +5 more sources

Evaluation of NACA and diNACA in human cystinosis fibroblast cell cultures as potential treatments for cystinosis

open access: yesOrphanet Journal of Rare Diseases, 2022
Background Cystinosis is a rare autosomal recessive lysosomal storage disease, associated with high morbidity and mortality. Mutations in the CTNS gene disable a membrane protein responsible for the transport of cystine out of the lysosome.
Emma Hector   +2 more
doaj   +1 more source

Characterization of the nonheme iron center of cysteamine dioxygenase and its interaction with substrates

open access: yesJournal of Biological Chemistry, 2020
Cysteamine dioxygenase (ADO) has been reported to exhibit two distinct biological functions with a nonheme iron center. It catalyzes oxidation of both cysteamine in sulfur metabolism and N-terminal cysteine-containing proteins or peptides, such as ...
Yifan Wang   +5 more
semanticscholar   +1 more source

Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids

open access: yesAdvanced Science, EarlyView.
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu   +9 more
wiley   +1 more source

Recent Research in Ocular Cystinosis: Drug Delivery Systems, Cysteamine Detection Methods and Future Perspectives

open access: yesPharmaceutics, 2020
Cystinosis is a rare genetic disorder characterized by the accumulation of cystine crystals in different tissues and organs. Although renal damage prevails during initial stages, the deposition of cystine crystals in the cornea causes severe ocular ...
Ana Castro-Balado   +12 more
semanticscholar   +1 more source

A novel approach to enhancing cellular glutathione levels [PDF]

open access: yes, 2008
20 pages, 9 figures, 1 table.-- PMID: 18702664 [PubMed].-- PMCID: PMC2644427.-- NIHMSID: NIHMS90383.-- Printed version published Nov 2008.Glutathione (GSH) and GSH-associated metabolism provide the major line of defense for the protection of cells from ...
Lewerenz, Jan   +3 more
core   +1 more source

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