Results 101 to 110 of about 935,449 (290)

The effects of PMSF and cysteine addition into partially purified bromelain from pineapple (Ananas comosus [L] Merr) cores to its kinetics behaviour [PDF]

, 2020
Siswati Setiasih, Mike Milo Diana Putri, Sri Handayani, Sumi Hudiyono   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Anchoring of Surface Proteins to the Cell Wall of Staphylococcus aureus: sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH2-Gly3 substrates [PDF]

, 2000
Staphylococcus aureus sortase anchors surface proteins to the cell wall envelope by cleaving polypeptides at the LPXTG motif. Surface proteins are linked to the peptidoglycan by an amide bond between the C-terminal carboxyl and the amino group of the ...
Faull, Kym F., Mazmanian, Sarkis K., Schneewind, Olaf, Ton-That, Hung   +3 more
core  

COA6 facilitates cytochrome c oxidase biogenesis as thiol-reductase for copper metallochaperones in mitochondria.

, 2020
The mitochondrial cytochrome c oxidase, the terminal enzyme of the respiratory chain, contains heme and copper centers for electron transfer. The conserved COX2 subunit contains the CuA site, a binuclear copper center.
Aich, A., Bogeski, I., Chacinska, A., Chudenkova, M., Deckers, M., Dennerlein, S., Gibhardt, C., Oeljeklaus, S., Pacheu-Grau, D., Rehling, P., Warscheid, B., Wasilewski, M.   +11 more
core   +2 more sources

Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and cerine residues in the Epstein-Barr Virus lytic switch protein [PDF]

, 2008
Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with various malignancies, including Burkitt's lymphoma and nasopharyngeal carcinoma.
A Prokhortchouk, AJ Sinclair, Alison J. Sinclair, Bill Sugden, C Petosa, C Schelcher, C Schelcher, Carlo Petosa, Celine Schelcher, E Flemington, EA Merritt, Elizabeth Verrall, F Watt, G Miller, KF Macsween, LS Young, M Gromiha, MR Hicks, MR Hicks, N Nagano, P Wang, PM Bhende, PM Bhende, Questa H. Karlsson, R Feederle, RJ Klose, RM Esnouf, SJ Bark-Jones, T Tsurumi, TA Jones, U Heinemann, YF Chiu   +31 more
core   +3 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread

Cell Reports
Summary: The inherent ability of melanoma cells to alter the differentiation-associated transcriptional repertoire to evade treatment and facilitate metastatic spread is well accepted and has been termed phenotypic switching. However, how these facets of
Deyang Yu, Jiaxin Liang, Hans R. Widlund, Pere Puigserver   +3 more
doaj   +1 more source

Removal of Cysteine (an Aliphatic Amino Acid) by Natural Clinoptilolite [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2011
Amino acids have been extensively used in several processes of the pharmaceutical and food industries. Treatments for the recovery and reuse of the wastewaters generated from these processes are few and little known.
Hossein Faghihian, Massoud Nejati-Yazdinejad   +1 more
doaj  

SUN/KASH interactions facilitate force transmission across the nuclear envelope. [PDF]

, 2019
LINC complexes (Linker of Nucleoskeleton and Cytoskeleton), consisting of inner nuclear membrane SUN (Sad1, UNC-84) proteins and outer nuclear membrane KASH (Klarsicht, ANC-1, and Syne Homology) proteins, are essential for nuclear positioning, cell ...
Hao, Hongyan, Starr, Daniel A
core  

Detecting peroxiredoxin hyperoxidation by one-dimensional isoelectric focusing [PDF]

, 2015
The activity of typical 2-cys peroxiredoxin (Prxs) can be regulated by hyperoxidation with a consequent loss of redox activity. Here we developed a simple assay to monitor the level of hyperoxidation of different typical 2-cys prxs simultaneously.
Bulleid, Neil J., Cao, Zhenbo
core   +1 more source