Results 71 to 80 of about 778,605 (292)

Cystatin C: Its role in pathogenesis of OSMF

open access: yesJournal of Oral Biology and Craniofacial Research, 2014
Oral Submucous Fibrosis (OSF) is a chronic disorder characterized by fibrosis of the mucosa lining the upper digestive tract involving the oral cavity, oro- and hypopharynx and the upper third of the oesophagus.
P.C. Anila Namboodiripad
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Ethylene Signaling Mediates a Maize Defense Response to Insect Herbivory

open access: yesMolecular Plant-Microbe Interactions, 2006
The signaling pathways that enable plants to mount defenses against insect herbivores are known to be complex. It was previously demonstrated that the insect-resistant maize (Zea mays L.) genotype Mp708 accumulates a unique defense cysteine proteinase ...
Antoine L. Harfouche   +4 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Recombinant production and characterisation of two Fasciola hepatica cathepsin L proteases [PDF]

open access: yes, 2005
The cysteine proteases of the liver fluke, Fasciola hepatica, are of great importance to the virulence of the organism. Previous work has established the involvement of these enzymes in catabolism, migration through host tissues and defence against host ...
Collins, Peter Raymond
core   +2 more sources

Obtaining of transgenic papaya plants var. Maradol roja that carry out the rice oryzacystatin gene

open access: yesBiotecnología Vegetal, 2004
Papaya (Carica papaya L.), is severely affected by Papaya Ringspot virus, which belongs to plant potyvirus group. A recent strategy for pest control produced by this virus is the transformation with genes encoding cysteine proteinase inhibitors.
Milady F. Mendoza   +6 more
doaj  

High glucose causes apoptosis of rabbit corneal epithelial cells involving activation of PERK-eIF2α-CHOP-caspase-12 signaling pathway [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To investigate the effect of high concentration of glucose (HCG) on double stranded RNA-activated protein kinase-like ER kinase (PERK)-eukaryotic initiation factor-2α (eIF2α)-transcription factor C/EBP homologous protein (CHOP)-cysteine aspartate ...
Pan-Pan Yao   +8 more
doaj   +1 more source

Digestive enzymes of vine weevil (Otiorhynchus sulcatus) as potential targets for insect control strategies. [PDF]

open access: yes, 2002
Over the previous quarter century the vine weevil (Otiorhynchus sulcatus) has become a pest of horticultural and agricultural plants. The vine weevil is a polyphagous coleopteran insect and is able to attack over one hundred different plant species.
Edwards, M.G., Edwards, Martin Gethin
core  

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

open access: yesAdvanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi   +5 more
wiley   +1 more source

Synergistic Effect of Nano-Sliver with Sucrose on Extending Vase Life of the Carnation cv. Edun

open access: yesFrontiers in Plant Science, 2017
We investigated the effects of sucrose and nano-silver (NAg) on extending the vase life of cut carnation flowers “Edun”. Sucrose (pulse treatment) suppressed ethylene production by downregulating the genes that code for its biosynthesis.
Da Y. Park   +6 more
doaj   +1 more source

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