Results 221 to 230 of about 753,077 (248)

Revisiting cysteine protease function in <i>Trypanosoma cruzi</i>: implications for parasite egress and differentiation. [PDF]

Microbiol Spectr
De Grandis S, Niggli A, Bogenstätter D, Lentini G.   +3 more
europepmc   +1 more source

Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött, Glenn Geidel, Carmen M. T. Roeper, Lucija Ačkar, Bente Siebels, Hannah Voß, Hartmut Schlüter, Michaela Schweizer, Kilian Müller, Alessandra Rünger, Tim Zell, Benjamin Deitert, Ali Zeinal‐Abedini, Isabel Heidrich, Stefan W. Schneider, Klaus Pantel, Daniel J. Smit, Christoffer Gebhardt   +17 more
wiley   +1 more source

Human Neutrophils Produce De Novo Thyroid Hormones Mediated by the Induction of the Oxidative Burst. [PDF]

Biomolecules
Bilal MY, Ganieva U, Luu T, Kwak-Kim J, Dambaeva S.   +4 more
europepmc   +1 more source

Comparative Transcriptome Analysis Reveals Expression of Defense Pathways and Specific Protease Inhibitor Genes in Solanum lycopersicum in Response to Feeding by Tuta absoluta. [PDF]

Insects
Zhou Y, Pan Y, Liu J, Yang W, Shen G.
europepmc   +1 more source

An upside to chronic inflammation? Starvation reconfigures immune pathways in Manduca sexta, producing chronic inflammation that may help defend against bacterial infection. [PDF]

PLoS One
Adamo SA, Burns MR, Englehardt MH, Grabtchak A, Kearney R, Martin CAE, Richmond MR.   +6 more
europepmc   +1 more source

Chikungunya virus nsP2: Insights into viral replication, pathogenesis, and therapeutic targeting. [PDF]

Virulence
Xu S, Li K, Tan Q, Yuan L, Huang R, Feng Y, Xu K, Zhu Z, Deng L, Deng Y, Ren Y, Yang J, Yang X.   +12 more
europepmc   +1 more source

Cruzain Inhibitors for Chagas Disease: Anticorrelated Optimisation Landscapes and the Multiparametric Path to Clinical Candidates. [PDF]

Chem Biol Drug Des
Dos Reis CRC, de Souza HVCM, Parra LC, de Souza GVCM, Zorzanelli BC, Boechat N, Hoelz LVB, Fernandes TVA.   +7 more
europepmc   +1 more source

Decoding Enzyme-Inhibitor Kinetic Mechanisms by Isothermal Titration Calorimetry: The Case of SARS-CoV-2 3CL^pro. [PDF]

Anal Chem
Mazzei L, Ranieri S, Silvestri D, Montelione GT, Ciurli S.   +4 more
europepmc   +1 more source

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Genealogy of mammalian cysteine proteinase inhibitors

FEBS Letters, 1985
Werner Müller-Esterl, Josef Kellermann, Werner Machleidt   +2 more
exaly  

Human plasma kininogens are identical with α-cysteine proteinase inhibitors

FEBS Letters, 1985
Werner Müller-Esterl, Josef Kellermann, Werner Machleidt   +2 more
exaly