Results 1 to 10 of about 38,369 (163)
A cysteine proteinase inhibitor ALLN alleviates bleomycin-induced skin and lung fibrosis [PDF]
Arthritis Research & Therapy, 2023 Background Systemic sclerosis (SSc) is a connective tissue disease that is characterized by fibrosis in the skin and internal organs, such as the lungs.
Hiroshi Kasamatsu +7 more
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A novel cysteine proteinase inhibitor from seeds of Enterolobium contortisiliquum and its effect on Callosobruchus maculatus larvae [PDF]
Biochemistry and Biophysics Reports, 2021 This study focused on the characterization of a novel cysteine proteinase inhibitor from Enterolobium contortisiliquum seeds targeting the inhibition of the growth of Callosobruchus maculatus larvae, an important cosmopolitan pest of the cowpea Vigna ...
Natalia N.S. Nunes +4 more
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Exploring the protease inhibitory potential of 2-bromo-2-nitro-1,3- propanediol (Bronopol): Initial findings [PDF]
Biochemistry and Biophysics ReportsThe compound 2-bromo-2-nitropropane-1,3-diol also known as Bronopol (BP) is a widely used antimicrobial preservative which highly soluble in water. Although its antimicrobial mechanism has been well described, its potential to modulate protease activity ...
Chao Jiang +2 more
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The Onchocerca volvulus cysteine proteinase inhibitor, Ov-CPI-2, is a target of protective antibody response that increases with age. [PDF]
PLoS Neglected Tropical Diseases, 2010 Despite considerable efforts, a suitable vaccine against Onchocerca volvulus infection has remained elusive. Herein, we report on the use of molecular tools to identify and characterize O.
Fidelis Cho-Ngwa +2 more
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Human Neutrophils Produce De Novo Thyroid Hormones Mediated by the Induction of the Oxidative Burst [PDF]
BiomoleculesThyroid hormone synthesis involves several key steps culminating in the organification of iodide into iodothyronines, thyroxine, and triiodothyronine. To date, there is no clear mechanistic evidence of extrathyroidal iodothyronine synthesis. Upon iodine (
Mahmood Y. Bilal +4 more
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Cystatins — Inhibitors of Cysteine Proteinases [PDF]
Critical Reviews in Oral Biology & Medicine, 1992 The cystatin superfamily of proteins, derived from a common ancestor, is comprised of a diverse group of potent cysteine proteinase inhibitors and antibacterial/viral agents grouped into several families. This review concentrates on family 2 cystatins, namely, the human salivary cystatins and cystatin C.
L A, Bobek, M J, Levine
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Fishes, 2022 Cysteine proteinase inhibitors (CPIs) protect tissues and organs against cysteine proteinases in animal blood and have attracted much attention for use in food processing and medical sciences for humans and animals.
Seong Hee Mun, Joon Yeong Kwon
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Frontiers in Immunology, 2022 To elucidate the application value of insect endogenous protease and its inhibitor genes in pest control, we analyzed in detail the transcriptome sequence of the Asian corn borer, Ostrinia furnacalis.
Ruobing Guan +7 more
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Melia azedarach L. extract induced the production of phytocystatin in passion fruit leaves
Hoehnea, 2021 Phytocystatins belong to the family of cysteine proteinases inhibitors. These proteinase inhibitors have crucial functions in plant defense against insects and pathogens attack. In the present study Melia azedarach L. extract acts as an elicitor of plant
Alyne Bispo Rodrigues +1 more
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Cysteine Proteinase Inhibitors in Murine Cysticercosis [PDF]
Antimicrobial Agents and Chemotherapy, 2006 ABSTRACT We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.
Salman, Baig +7 more
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