A novel inhibitor protein for Bombyx cysteine proteinase is homologous to propeptide regions of cysteine proteinases [PDF]
FEBS Letters, 1999 A cDNA clone for an inhibitor of Bombyx cysteine proteinase was isolated and sequenced. Active inhibitor proteins were expressed in Escherichia coli using the cDNA. The open reading frame of the cDNA encodes a 105 residues protein with 19 residues of a signal sequence.
Y, Yamamoto +3 more
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The primary structure of inhibitor of cysteine proteinases from potato [PDF]
FEBS Letters, 1993 The complete amino acid sequence of the cysteine proteinase inhibitor from potato tubers was determined. The inhibitor is a single‐chain protein having 180 amino acid residues. Its primary structure was elucidated by automatic degradation of the intact protein and sequence analysis of peptides generated by CNBr, trypsin and glycyl endopeptidase.
Kriz̆aj, I. +4 more
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Bacterial expression of human cysteine proteinase inhibitor stefin A
FEBS Letters, 1989 Gene expression system; DNA, recombinant; Stefin A; Cystatin ...
Fong, Dunne +3 more
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BMC Plant Biology, 2012 Background Cysteine proteinases perform multiple functions in seeds, including participation in remodelling polypeptides and recycling amino acids during maturation and germination.
Lepelley Maud +5 more
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Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]
, 2000 The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard +3 more
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Protective effect of latex proteins from Plumeria pudica against acetaminophen-induced acute liver injury [PDF]
Anais da Academia Brasileira de CiênciasThe protein fraction from Plumeria pudica latex (LPPp) was evaluated against APAP-induced liver injury in mice. Key measurements included total leukocyte count, liver weight, AST, ALT, liver levels of MDA, GSH, SOD, MPO, NO3/NO2 concentration, cytokines ...
BRUNA DA SILVA SOUZA +20 more
doaj +2 more sources
Selective loss of cysteine residues and disulphide bonds in a potato proteinase inhibitor II family. [PDF]
PLoS ONE, 2011 Disulphide bonds between cysteine residues in proteins play a key role in protein folding, stability, and function. Loss of a disulphide bond is often associated with functional differentiation of the protein.
Xiu-Qing Li +2 more
doaj +1 more source
Cysteine peptidases and their inhibitors in breast and genital cancer.
Folia Histochemica et Cytobiologica, 2010 Cysteine proteinases and their inhibitors probably play the main role in carcinogenesis and metastasis. The metastasis process need external proteolytic activities that pass several barriers which are membranous structures of the connective tissue which ...
Magdalena Milan +7 more
doaj +1 more source
The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases [PDF]
Biochemical Journal, 1986 A synthesis of peptidylfluoromethanes is described that utilizes the conversion of phthaloyl amino acids into their fluoromethane derivatives. These can be deblocked and elongated. The inactivation of chymotrypsin by Cbz-Phe-CH2F (benzyloxycarbonylphenylalanylfluoromethane) was found to be considerably slower than that of the analogous chloromethane ...
P, Rauber +3 more
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The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines [PDF]
, 2011 Supplementary to the efficient inhibition of trypsin, chymotrypsin, plasma kallikrein, and plasmin already described by the EcTI inhibitor from Enterolobium contortisiliquum, it also blocks human neutrophil elastase (K(iapp)=4.3 nM) and prevents phorbol ...
Sampaio, Misako U. [UNIFESP] +21 more
core +1 more source