A novel inhibitor protein for Bombyx cysteine proteinase is homologous to propeptide regions of cysteine proteinases [PDF]
A cDNA clone for an inhibitor of Bombyx cysteine proteinase was isolated and sequenced. Active inhibitor proteins were expressed in Escherichia coli using the cDNA. The open reading frame of the cDNA encodes a 105 residues protein with 19 residues of a signal sequence.
Y, Yamamoto +3 more
openaire +4 more sources
The primary structure of inhibitor of cysteine proteinases from potato [PDF]
The complete amino acid sequence of the cysteine proteinase inhibitor from potato tubers was determined. The inhibitor is a single‐chain protein having 180 amino acid residues. Its primary structure was elucidated by automatic degradation of the intact protein and sequence analysis of peptides generated by CNBr, trypsin and glycyl endopeptidase.
Kriz̆aj, I. +4 more
openaire +4 more sources
Inhibition of cysteine proteinases by a protein inhibitor from potato [PDF]
The inhibitory specificity of a protein from potato tubers that inhibits cysteine proteinases (potato cysteine proteinase inhibitor, PCPI) has been compared with that of chicken egg‐white cystatin. Most proteinases that are inhibited by cystatin were also inhibited by PCPI, but the potato inhibitor inhibited stem bromelain and fruit bromelain, which ...
Rowan, Andrew D. +3 more
openaire +3 more sources
Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB [PDF]
Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping
Mottram, Jeremy C +5 more
core +4 more sources
Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]
Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F. +11 more
core +4 more sources
Fusarium oxysporum f. sp. cubense tropical race 4 (FocTR4) is a destructive necrotrophic fungal pathogen afflicting global banana production. Infection process involves the activation of programmed cell death (PCD).
Wan Muhamad Asrul Nizam Wan Abdullah +7 more
doaj +1 more source
Background Cysteine proteinases perform multiple functions in seeds, including participation in remodelling polypeptides and recycling amino acids during maturation and germination.
Lepelley Maud +5 more
doaj +1 more source
Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]
The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard +3 more
core +1 more source
Protective effect of latex proteins from Plumeria pudica against acetaminophen-induced acute liver injury [PDF]
The protein fraction from Plumeria pudica latex (LPPp) was evaluated against APAP-induced liver injury in mice. Key measurements included total leukocyte count, liver weight, AST, ALT, liver levels of MDA, GSH, SOD, MPO, NO3/NO2 concentration, cytokines ...
BRUNA DA SILVA SOUZA +20 more
doaj +2 more sources
Cysteine peptidases and their inhibitors in breast and genital cancer.
Cysteine proteinases and their inhibitors probably play the main role in carcinogenesis and metastasis. The metastasis process need external proteolytic activities that pass several barriers which are membranous structures of the connective tissue which ...
Magdalena Milan +7 more
doaj +1 more source

