Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu+4 more
wiley +1 more source
Motif mapping during chickpea germination reveals a complex sequential activation of different proteolytic activities. [PDF]
Bera I+4 more
europepmc +1 more source
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt+2 more
wiley +1 more source
A Mg<sup>2+</sup>-dependent high-yield method for extracting high-molecular-weight genomic DNA from a single planarian specimen. [PDF]
Li A+7 more
europepmc +1 more source
Identifying health‐promoting molecules such as bioactive peptides in complex food mixtures is a major challenge. In this study, we investigated proteins and protein hydrolysates from four quinoa varieties to evaluate their potential anticancer effects on colorectal adenocarcinoma cells.
Alessandro Zaccarelli+6 more
wiley +1 more source
Purification of a cysteine proteinase inhibitor from rice, Oryza sativa L. japonica.
Keiko Abe, Soichi Arai
openalex +2 more sources
Molecular basis of pyruvate transport and inhibition of the human mitochondrial pyruvate carrier. [PDF]
Sichrovsky M+21 more
europepmc +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Insights into Octopus maya cathepsins from metatranscriptome and genome: structure evolutionary relationships and functional role prediction in digestive processes. [PDF]
Pineda-Suazo D+4 more
europepmc +1 more source