Results 331 to 340 of about 47,940 (359)

Acidic Cysteine Proteinase Inhibitor in Seminal Plasma

Biological Chemistry Hoppe-Seyler, 1985
A cysteine proteinase inhibitor with acidic isoelectric point (pI = 4.7-5.0) was found in human seminal plasma. Its apparent molecular mass is 16 kDa. It inhibits cysteine proteinases like ficin, cathepsin H, cathepsin B and papain. The inhibitory activity of seminal plasma against ficin is almost the same as that of human serum.
Kayoko Minakata, Minoru Asano
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Inhibitors of 3C Cysteine Proteinases from Picornaviridae

Current Topics in Medicinal Chemistry, 2004
The Picornaviridae are among the smallest icosahedral positive-sense single stranded RNA containing viruses known, and comprise one of the largest and most important families of human and animal pathogens. The hepatitis A virus (HAV) and human rhinovirus (HRV) are important pathogens that belong to the picornavirus family.
Rajendra Parasmal Jain, John C. Vederas, Manjinder S. Lall   +2 more
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Cysteine proteinase inhibitors of the canine intervertebral disc

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1988
Several species of cysteine proteinase inhibitors have been demonstrated in the greyhound intervertebral disc which were resolved into four species (Mr 15,800, 16,600, 17,200 and 17,800) by gelatin-SDS-polyacrylamide gel electrophoresis. Reductive alkylation did not affect their inhibitory capability nor their electrophoretic migration on gelatin-SDS ...
Tak-Chun Cole, James Melrose, Peter Ghosh   +2 more
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Cysteine proteinase inhibitors produced by mononuclear phagocytes

Cell and Tissue Research, 1984
Monocytes were separated from human peripheral blood and allowed to attach to culture flasks, after which the content and production of a number of cysteine proteinase inhibitors was assayed. These were: a low molecular weight (MW 12000) acid cysteine proteinase inhibitor (ACPI); a low-molecular weight inhibitor of the same size with neutral pH (NCPI),
Mikko Järvinen, I. Joronen, Aalto M, Ari Rinne, Väinö K. Hopsu-Havu   +4 more
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Bullfrog plasma cysteine proteinase inhibitor (CPI)

Immunopharmacology, 1996
Papain is inhibited by bullfrog plasma. CPI was isolated from bullfrog plasma by two step column chromatography; Cm-papain agarose column chromatography followed by FPLC Mono Q column chromatography with addition of benzamidine. Isolated CPI gave a single band on SDS-PAGE under reducing condition, and the molecular weight of reduced CPI was estimated ...
Hiroshi Mashiko, Hidenobu Takahashi
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Caiman Kininogen-Like Cysteine Proteinase Inhibitor

1992
Kininogens are the major mammalian plasma cysteine proteinase inhibitors; a kininogen-like protein was also found in the snake Bothrops jararaca plasma. This communication describes a kininogen-like protein in plasma of Caiman crocodilus vacare. Caiman crude plasma, unlike snake plasma, contains a detectable cysteine proteinase inhibitor. The inhibitor
Mariana S. Araujo, Sampaio Ca, Misako U. Sampaio, Chudzinski Am, Andreotti R   +4 more
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Cysteine proteinase inhibitors in elapid and hydrophiid snake venoms

Toxicon, 2002
The ability of elapid and hydrophiid snake venoms to inhibit cathepsin L was tested. All nine species of elapid and three species of hydrophiid snake venoms tested showed inhibition against cathepsin L. All of these venoms tested also showed inhibition against papain as well as against cathepsin L. Among these venoms, two elapid (Laticauda semifasciata
Hiroshi Mashiko, Hidenobu Takahashi
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Cathepsin D inactivates cysteine proteinase inhibitors cystatins

Biochemical and Biophysical Research Communications, 1988
The formation of inactive complexes in excess molar amounts of human cathepsins H and L with their protein inhibitors human stefin A, human stefin B and chicken cystatin at pH 5.6 has been shown by measurement of enzyme activity coupled with reverse-phase HPLC not to involve covalent cleavage of the inhibitors.
P. Lučovnik, Iztok Dolenc, Brigita Lenarčič, Vito Turk, Igor Križaj, Janko Kos   +5 more
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Assay of α-Cysteine Proteinase Inhibitor in Serum or Plasma

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1982
A new proteinase inhibitor has recently been found in human serum or plasma which specifically inhibits cysteine proteinases such as ficin, papain, bromelain and cathepsin B. However, serum contains alpha 2-macroglobulin which also inhibits these cysteine proteinases and, consequently, interferes with the assay of the new alpha-cysteine proteinase ...
Kayoko Minakata, Naoko Harada, Minoru Asano, Tomoaki Sato   +3 more
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Azapeptides as Inhibitors and Active Site Titrants for Cysteine Proteinases

Journal of Medicinal Chemistry, 1998
Ester and amide derivatives of alpha-azaglycine (carbazic acid, H2NNHCOOH), alpha-azaalanine, and alpha-azaphenylalanine (i.e., Ac-l-Phe-NHN(R)CO-X, where X = H, CH3, or CH2Ph, respectively) were synthesized and evaluated as inhibitors of the cysteine proteinases papain and cathepsin B.
Robert P. Hanzlik, Ruye Xing
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