Results 111 to 120 of about 53,318 (217)

Type 2 Innate Lymphoid Cell Activation by Cysteinyl Leukotrienes : : a Novel Mechanism of Lipid-Mediated Allergic Inflammation [PDF]

, 2014
Type 2 innate lymphoid cells (ILC2) are a novel population of innate lymphocytes lacking expression of lineage markers. ILC2 lack antigen specificity and are instead activated by epithelial cytokines IL-33 and IL-25.
Lund, Sean Joseph
core  

Blocking leukotriene receptors improve experimentally induced gastric ulcers in rats by inhibiting inflammation and apoptosis

International Journal of Immunopathology and Pharmacology
To investigate whether obstructing the cysteinyl leukotriene receptor-1 (CYSLTR1) with zafirlukast diminishes experimentally induced gastric ulcer (GU) in rats by modulating inflammation and apoptosis.
Hanan M. Hassan, Alaa Bagalagel, Reem Diri, Ahmad Noor, Deina Almasri, Douha F. Bannan, Mohammed Z. Nasrullah, Mohammed M. H. Al-Gayyar   +7 more
doaj   +1 more source

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: Critical update and emerging trends

, 2007
Cysteinyl-leukotrienes (cysteinyl-LTs), i.e. LTC4, LTD4, and LTE4, trigger contractile and inflammatory responses through the specific interaction with G protein-coupled receptors (GPCRs) belonging to the purine receptor cluster of the rhodopsin family ...
Giancarlo Folco, Angelo Sala, G. Enrico Rovati, V. Capra, M. D. Thompson, D. E. Cole, A. Sala, David E. Cole, G. Folco, Valérie Capra, G. Rovati, Miles D. Thompson   +11 more
core   +1 more source

Chlorine Gas, Airway Inflammation, and Cysteinyl Leukotrienes: The Neutrophil Does Not Work Alone. [PDF]

Am J Respir Cell Mol Biol, 2020
Sporn PHS.
europepmc   +1 more source

Leukotriene C_4 in Combination with Transforming Growth Factor-β Augments Extracellular Matrix Production from Human Lung Fibroblasts [PDF]

, 2004
Airway remodeling has an important role in the pathogenesis of bronchial asthma and is associated with severe, intractable disease. A lot of mediators, especially cysteinyl leukotrienes (CysLTs) and transforming growth factor (TGF)-β that influence ...
Asakura, Takuma, Chibana, Kazuyuki, Ishii, Yoshiki   +2 more
core  

Cysteinyl leukotriene receptors promote melanoma progression and metastasis

Translation
Emma Elizabeth Sabu Kattuman, Lakshminarayan Reddy Teegala, Somayeh Darzi, Sailaja Paruchuri   +3 more
doaj   +3 more sources

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Functional characterisation of receptors for cysteinyl leukotrienes in smooth muscle [Elektronisk resurs]

, 1998
The cysteinyl leukotrienes (leukotriene C4, D4 and E4) have potent biological actions which significantly contribute to the airway obstruction in asthma.
Wikström, Jonsson E,
core  

Novel cysteinyl leukotriene biology in human airways

, 2004
Cysteinyl leukotrienes (LTC4 , D4 , E4 ) play an important role in the pathophysiology of asthma. They produce bronchoconstriction, microvascular leakage and eosinophil infiltration into the airway mucosa.
Nair, Parameswaran K.
core   +1 more source

The Orphan Receptor GPR17 Is Unresponsive to Uracil Nucleotides and Cysteinyl Leukotrienes

Molecular Pharmacology, 2017
Katharina Simon, Nicole Merten, R. Schröder, Stephanie Hennen, Philip Preis, Nina Schmitt, L. Peters, R. Schrage, C. Vermeiren, M. Gillard, K. Mohr, J. Gomeza, E. Kostenis   +12 more
semanticscholar   +1 more source