Results 91 to 100 of about 53,318 (217)
Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
Journal of Experimental Medicine, 2011 Dectin-2 expression on GM-CSF–cultured bone marrow cells is required for the generation of cysteinyl leukotrienes and Th2 cytokines in response to the house dust mite Dermatophagoides farinae in vivo.
Nora A. Barrett +6 more
semanticscholar +1 more source
, 1999 Hyperresponsiveness to histamine is a key feature of a variety of pathological conditions, including bronchial asthma, food allergy, colitis ulcerosa, and topical allergic disorders.
Peppelenbosch, M. P. +7 more
core
EFFECTS OF CYSTEINYL LEUKOTRIENES ON PLATELET ACTIVATION [PDF]
, 2016 Platelet are key players in haemostasis and represent a pivotal link between inflammation, immunity and atherogenesis. Cysteinyl leukotrienes (CysLTs) such as LTC4, LTD4, and LTE4 are potent lipid inflammatory mediators which interact with G protein ...
V. Caroppo
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The role of cysteinyl leukotrienes in chronic inflammation and neoplasia of the intestine
, 2009 It has recently been demonstrated that cysteinyl leukotrienes are involved in a variety of proinflammatory and neoplastic functions. This article gives an up-to-date overview of the present knowledge of these bioactive lipid molecules. Inflammatory bowel
Broom, Oliver Jay, Nielsen, Ole Haagen
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Cysteinyl-Leukotrienes in Cerebrovascular Disease [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 Although the initial interest in the field of leukotriene (LT) research was focused on their potent bronchoconstrictive effects, subsequent studies have suggested LTs as key mediators in several inflammatory diseases. Genetic variations within the enzymes transforming arachidonic acid into LTs (Figure) have for example been associated with ...
openaire +1 more source
Inflammatory Mediators in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology, 1990 Tissue responses to an inflammatory stimulus (such as vasodilation, plasma exudation invasion and activation of inflammatory cells) are elicited by locally synthesized chemical mediators.
BM Peskar
doaj +1 more source
[Cysteinyl leukotrienes and their receptors].
Postepy biochemii, 2010 Cysteinyl leukotrienes (LTC4, LTD4, LTE4) have a proinflamation effect, such as contraction of blood vessels smooth muscle and the respiratory tract, chemotaxis of proinflammatory cells increased endothelium cells permeability and mucus secretion. They are lipid mediators playing an important part in the pathophysiology of bronchial asthma, allergic ...
Karolina, Wódz-Naskiewicz +1 more
openaire +1 more source
Acta Medica Iranica, 2013 The leukotrienes and prostaglandins are biologically active metabolites derived from arachidonic acid. The leukotrienes have a role in inflammatory diseases such as allergic rhinitis, inflammatory bowel disease and asthma.
Ali Asghar Hemmati +2 more
doaj
Lipid mediators in plasma of autism spectrum disorders
Lipids in Health and Disease, 2012 Background Inflammation is increasingly recognized as being of both physiological and pathological importance in the immature brain. Cerebellar pathology occurs in autism, as a neurodevelopmental disorder with genetic and environmental origins.
El-Ansary Afaf, Al-Ayadhi Laila
doaj +1 more source
Journal of Pharmacological Sciences, 2009 The actions of cysteinyl leukotrienes (CysLTs) are mediated by activating CysLT receptors, CysLT1, and CysLT2. The CysLT1 receptor mediates vascular responses to CysLTs; however, its effect on the proliferation and migration of endothelial cells is not ...
Yu-Mei Yuan +9 more
doaj +1 more source