Results 151 to 160 of about 53,318 (217)

Context-dependent regulation of mast cell-mediated food allergy in C57BL/6J mice. [PDF]

J Allergy Clin Immunol
Perez NM, Ranjitkar S, Jordan N, Gregory KJ, Schneider SS, Dwyer DF, Mathias CB.   +6 more
europepmc   +1 more source

IL-33 Elicits LTC₄ Synthesis in Allergic Inflammation via ST2-Mediated Activation of Eosinophils. [PDF]

Eur J Immunol
Rosário-Garcia VF, Guimaraes-Ferreira E, Brito-Leite Y, Oliveira JF, Santos-da-Silva J, Amorim NRT, Muniz VS, Bolini L, Werneck MBF, Canetti C, Diaz BL, Bandeira-Melo C.   +11 more
europepmc   +1 more source

A Tuft Cell-Dependent Pathway Linking Intestinal and Cognitive Health. [PDF]

Cell Mol Gastroenterol Hepatol
Edens-Valentine R, Engevik AC.
europepmc   +1 more source

Montelukast and Bilastine Combination Therapy in Allergic Rhinitis: A Narrative Review of Evidence. [PDF]

Cureus
Jindal S, Shah NN, Jain P, Patil K, Bhargave C, Khandhedia C, Mehta S.   +6 more
europepmc   +1 more source

Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters [PDF]

Science immunology, 2022
The gallbladder stores bile between meals and empties into the duodenum upon demand and is thereby exposed to the intestinal microbiome. This exposure raises the need for antimicrobial factors, among them, mucins produced by cholangiocytes, the dominant ...
M. Keshavarz, Schayan Faraj Tabrizi, Anna-Lena Ruppert, U. Pfeil, Y. Schreiber, J. Klein, Isabell Brandenburger, G. Lochnit, S. Bhushan, Alexander Perniss, K. Deckmann, P. Hartmann, Mirjam Meiners, Petra Mermer, A. Rafiq, S. Winterberg, T. Papadakis, Dominique Thomas, C. Angioni, J. Oberwinkler, V. Chubanov, T. Gudermann, U. Gärtner, S. Offermanns, B. Schütz, W. Kummer   +25 more
semanticscholar   +2 more sources

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A novel therapeutic potential of cysteinyl leukotrienes and their receptors modulation in the neurological complications associated with Alzheimer's disease

European Journal of Pharmacology, 2019
Cysteinyl leukotrienes (cysLTs) are member of eicosanoid inflammatory lipid mediators family produced by oxidation of arachidonic acid by action of the enzyme 5-lipoxygenase (5-LOX).
Salman Hussain, Syed Obaidur Rahman, Mohd Akhtar   +2 more
exaly   +2 more sources

Eosinophils and cysteinyl leukotrienes

Prostaglandins Leukotrienes and Essential Fatty Acids, 2003
Eosinophils are the main source of the cysteinyl leukotrienes, LTC(4)/D(4)/E(4), which are lipid mediators that play major roles in the pathogenesis of asthma and other forms of allergic inflammation. Here, we review the mechanisms governing eosinophil LTC(4) synthesis, focusing on the distinct intracellular domains that regulate eicosanoid formation ...
Peter F Weller, Christianne Bandeira-Melo   +1 more
exaly   +3 more sources

Cysteinyl leukotrienes regulate TGF-β1 and collagen production by bronchial fibroblasts obtained from asthmatic subjects

Prostaglandins Leukotrienes and Essential Fatty Acids, 2012
Jamila Chakir
exaly   +2 more sources

Cough, asthma, and cysteinyl-leukotrienes.

Pulmonary Pharmacology & Therapeutics, 2013
Asthma is a chronic inflammatory disease of the lower airways, involving various cells such as eosinophils, and cytokines and mediators. Cyteinyl-leukotrienes (cys-LTs) are one of the chemical mediators that play major pathophysiological roles in asthma.
A. Niimi
semanticscholar   +3 more sources