Results 141 to 150 of about 1,132,527 (387)

Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis–based cell and mice models [PDF]

open access: gold, 2020
Anindit Mukherjee   +5 more
openalex   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai   +8 more
wiley   +1 more source

Measuring the burden of treatment for chronic disease: implications of a scoping review of the literature [PDF]

open access: yes, 2017
Background: Although there has been growing research on the burden of treatment, the current state of evidence on measuring this concept is unknown.
Mair, Frances S.   +3 more
core   +3 more sources

The impact of impaired macrophage functions in cystic fibrosis disease progression [PDF]

open access: bronze, 2016
Manuella Lévêque   +3 more
openalex   +1 more source

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

open access: yesAnnals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang   +10 more
wiley   +1 more source

Improving the Rate of Sufficient Sweat Collected in Infants Referred for Sweat Testing in Michigan

open access: yesGlobal Pediatric Health, 2014
Objective . Sweat collected for testing should have quantity not sufficient (QNS) rate of ≤10% in babies ≤3 months of age. Michigan (MI) cystic fibrosis (CF) centers’ QNS rates were 12% to 25% in 2009. This project was initiated to reduce sweat QNS rates
Ibrahim Abdulhamid MD   +6 more
doaj   +1 more source

Global impact of bronchiectasis and cystic fibrosis [PDF]

open access: diamond, 2016
Margarida Redondo   +3 more
openalex   +1 more source

Eradication of Burkholderia cepacia Using Inhaled Aztreonam Lysine in Two Patients with Bronchiectasis

open access: yesCase Reports in Pulmonology, 2014
There are not many articles about the chronic bronchial infection/colonization in patients with underlying lung disease other than cystic fibrosis (CF), especially with non-CF bronchiectasis (NCFBQ). The prevalence of B. cepacia complex is not well known
A. Iglesias   +4 more
doaj   +1 more source

Bicarbonate in cystic fibrosis [PDF]

open access: bronze, 2017
Karl Kunzelmann   +2 more
openalex   +1 more source

Downregulation of epithelial sodium channel (ENaC) activity in cystic fibrosis cells by epigenetic targeting [PDF]

open access: hybrid, 2022
Giovanna Blaconà   +8 more
openalex   +1 more source

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