Results 191 to 200 of about 89,217 (286)

Wogonoside Modulates the Nrf2/SLC40A1 Signaling Axis to Combat Inflammatory Osteolysis

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
This study explores the potential of wogonoside, a flavonoid from Scutellaria baicalensis, for treating inflammatory osteolysis and provides compelling experimental evidence supporting its promise as a functional food ingredient to alleviate associated bone loss.
Siyuan Zhou   +6 more
wiley   +1 more source

Probiotics and Curcumin Did Not Alter Low‐Dose Streptozotocin‐Induced Hyperglycemia and Oxidative Stress in a Rat Model

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
In this study, a high‐fat diet/streptozotocin‐induced type 2 diabetes rat model was used to evaluate the individual and combined effects of the multi‐strain probiotic VSL#3 and curcumin on glycemic control, insulin resistance, and oxidative stress–related outcomes.
Cavdar Meliha   +2 more
wiley   +1 more source

Müller Glial Kir4.1 Channel Dysfunction in APOE4‐KI Model of Alzheimer's Disease

open access: yesGlia, Volume 74, Issue 3, March 2026.
APOE4 impairs Müller cell health by reducing Kir4.1 expression and buffering. APOE4 causes mitochondrial dysfunction with decreased ΔΨm and increased ROS. MitoQ restores Kir4.1 expression and reduces ROS in APOE4‐transfected cells. ABSTRACT Alzheimer's disease (AD), particularly late‐onset AD (LOAD), affects millions worldwide, with the apolipoprotein ...
Surabhi D. Abhyankar   +8 more
wiley   +1 more source

Neutrophil Gelatinase‐Associated Lipocalin and Neutrophil‐to‐Lymphocyte Ratio as Indicators of Nephropathy in Type 2 Diabetic Mellitus Patients in Ghana: A Case‐Control Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Introduction Serum neutrophil gelatinase‐associated lipocalin (sNGAL), a renal tubular marker, and neutrophil‐to‐lymphocyte ratio (NLR), a hematological inflammatory marker are two biomarkers that have recently received attention, because of their association with kidney disease. This study examined the diagnostic value sNGAL and NLR in type 2
Allwell Adofo Ayirebi   +18 more
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

open access: yesIbrain, Volume 12, Issue 1, Page 3-37, Spring 2026.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma   +3 more
wiley   +1 more source

Dietary salt and protein intake and urinary cystine excretion in patients with cystinuria. [PDF]

open access: yesClin Kidney J
Bermond F   +11 more
europepmc   +1 more source

Organoids for Metabolic Disease Modeling

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic diseases (IMDs) are a diverse group of rare genetic disorders that disrupt metabolic pathways, leading to severe clinical manifestations. Disease models ranging from complex animal models to simple in vitro systems have provided insights into IMDs, but each has limitations.
Arif Ibrahim Ardisasmita   +2 more
wiley   +1 more source

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