Results 241 to 250 of about 47,323 (291)

Effect of a New Skin‐Lightening Cosmetic Containing Cordyceps Extract in the Treatment of Melasma: A Clinical Trial

Journal of Cosmetic Dermatology, Volume 24, Issue 7, July 2025.
ABSTRACT Background Cordyceps is a valuable Chinese herbal medicine known for its various components with antioxidant properties, which may theoretically improve melasma. This study aimed to evaluate the efficacy of a new skin‐lightening cosmetic containing Cordyceps extract (referred to as Cordyceps essence) in treating female patients with melasma ...
Sihao Shen, Huiyi Yao, Yuan Zhu, Wenzhong Xiang   +3 more
wiley   +1 more source

Ferroptosis: a novel perspective on tumor immunotherapy. [PDF]

Front Immunol
Xu Y, Ge M, Xu Y, Yin K.
europepmc   +1 more source

Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley   +1 more source

Mitigation of Ferroptosis in Diabetic Kidney Disease Through Mesenchymal Stem Cell Intervention via the Smad2/3/METTL3/S1PR1 Axis

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
MSCs modulate ferroptosis in DKD via Smad2/3/METTL3/S1PR1 axis. ABSTRACT Diabetic kidney disease (DKD) is a leading cause of end‐stage renal disease (ESRD) and is associated with heightened cardiovascular risk and increased overall mortality. Although mesenchymal stem cells (MSCs) have demonstrated therapeutic potential in DKD, their precise mechanisms
Li‐Lan Huang, Yue‐Yuan Hou, Ji Yang, Xing‐Na Liao, Jin‐Sha Ma, Wen‐Chao Wang, Yi‐Xiao Quan, Hong‐Ying Jiang, Yi‐Hua Bai   +8 more
wiley   +1 more source

Risk stratification for repeat stone surgery: the role of stone composition. [PDF]

World J Urol
Shpitzer SA, Shpunt I, Loebl N, Perl L, Enikeev D, Darawsha AE, Ehrlich Y, Lifshitz D.   +7 more
europepmc   +1 more source

An N‐Terminally Elongated Peptide From Conus rolani Defines a New Class of Ribbon α‐Conotoxins Targeting Muscle nAChRs

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
α‐RoIA is an atypical N‐terminally elongated conotoxin discovered in Conus rolani. N‐terminal elongation delays activity in vivo; however, this elongation must be removed to block muscle nicotinic acetylcholine receptors (nAChRs). Only the truncated ribbon isoform of RoIA blocks muscle nAChRs.
Matías L. Giglio, Paula Flórez‐Salcedo, Layla Azam, Maren Watkins, Thomas Lund Koch, Erianna Basgall‐De la Rosa, Adam D. Douglass, J. Michael McIntosh, Baldomero M. Olivera, Joanna Gajewiak   +9 more
wiley   +1 more source

Promising roles of vitamin D receptor and APRO family proteins for the development of cancer stem cells targeted malignant tumor therapy. [PDF]

Oncol Res
Nakashima M, Suga N, Fukumoto A, Yoshikawa S, Matsuda S.   +4 more
europepmc   +1 more source

Integrating Single‐Cell and Experimental Analyses Uncover Macrophage Ferroptosis Is a Key Event in the Development of Chronic Obstructive Pulmonary Disease

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
This study aims to uncover the molecular mechanism by which cigarette smoke (CS) promotes COPD progression. First, through single‐cell sequencing of alveolar lavage fluid in COPD patients, combined with transcriptomic data analysis from public databases (GSE171541, GSE173896), abnormal activation of macrophage ferroptosis pathway was found.
Xiaomei Duan, Tingting Hu, Ehbal Tuyghun, Zheng Li, Jing Jing, Dan Xu, Lijuan Xu, Jianbing Ding, Fengsen Li, Min Jiang, Jing Wang   +10 more
wiley   +1 more source

CRL3 E3 ligase regulates glutamine and cystine metabolisms. [PDF]

Protein Cell
Zhou Q, Li Z, Sun Y.
europepmc   +1 more source