Results 71 to 80 of about 95,243 (337)

Gas-Phase Fragmentation Reactions of Protonated Cystine using High-Resolution Tandem Mass Spectrometry

Molecules, 2019
Cystine is an important biomolecule in living systems. Although collision-induced dissociation (CID)-based tandem mass spectrometry (MS/MS) is commonly applied for identification and quantification of cystine in both biomedical and nutritional studies ...
Pengwei Zhang, Wan Chan, Irene L. Ang, Rui Wei, Melody M. T. Lam, Kate M. K. Lei, Terence C. W. Poon   +6 more
doaj   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

Protein & Cell, 2020
The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutathione biosynthesis and antioxidant defense and is overexpressed in multiple human cancers.
Pranavi Koppula, Li Zhuang, Boyi Gan
doaj   +1 more source

A retrospective study on epidemiology and management of canine cystine uroliths in one part of Norway from 2015 to 2020

Acta Veterinaria Scandinavica, 2023
Background Urinary tract problems are a common complaint in small animal medicine and urolithiasis is considered to be an important cause of urinary tract disease in dogs.
Terese Vatne Naeverdal, Janne Eidissen Midtgård, Ann-Katrin Llarena, Martine Lund Ziener   +3 more
doaj   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

The efficacy of choline as an adjuvant in the therapy of Laennec's cirrhosis [PDF]

, 1951
Thesis (M.D.)—Boston ...
Bednarz, Wallace
core  

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source

Cystine nephrolithiasis: contemporary approaches to patient management

Вестник урологии
Introduction. Cystinuria is a rare genetic disorder characterised by a markedly elevated concentration of cystine in the urine. Due to the low solubility of cystine in urine, patients with cystinuria face a lifelong increased risk of urinary stone ...
V. A. Gelig, E. I. Leonova, D. S. Gorelov, I. V. Semenyakin, N. K. Gadzhiev   +4 more
doaj   +1 more source

Selective, Simple and Economical Method for the Voltammetric Determination of Bi(III) in the presence Cystine in Non – Complexing Solution

E3S Web of Conferences, 2013
The simple and fast method for the determination of Bi(III) in non-complexing solution was proposed. The catalytic activity of cystine on Bi(III) ions electroreduction process were utilized.
Nosal –Wiercińska A., Grochowski M., Tyszczuk–Rotko K., Skrzypek S., Guziejewski D.   +4 more
doaj   +1 more source

Biosynthesis of food constituents: Amino acids. 3. Modified proteinogenic amino acids - a review

Czech Journal of Food Sciences, 2006
This review article gives a survey of principal pathways that lead to the biosynthesis of the modified principal proteinogenic amino acids, i.e. cystine, 4-hydroxyproline, 5-hydroxylysine, 3-methylhistidine, and O-phosphoserine.
Jan Velíšek, Karel Cejpek
doaj   +1 more source