Results 61 to 70 of about 55,240 (308)
Contents of Urinary System Stones in North Marmara Region and Their Distribution by Gender
Journal of Urological Surgery, 2020 Objective:We aimed to determine the contents of kidney stones in our country by evaluating the results of the stone analysis of patients who underwent surgery due to ureteral or kidney stones or experienced spontaneous stone expulsion.Materials and ...
Ekrem Güner, Kamil Gökhan Şeker
doaj +1 more source
Advanced Science, EarlyView.FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang +11 more
wiley +1 more source
Cystine-deprived CD8 T cells-RNA seq.rar
CD8 T cells were cultured in normal medium (NM) and cystine-deprived medium (CD, 20 μmmol/L cystine), and these CD8 T cells were then subjected to RNA sequencing.
Chenfeng Han (17718669)
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Advanced Science, EarlyView.Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong +4 more
wiley +1 more source
Low‐Level Arsenic Removal from Drinking Water
Global Challenges, 2019 The reported ability of cysteine and cystine to bind typical arsenic oxy‐ions in water is used as a basis for a study of the potential for using a surfactant with a cysteine head‐group for selective arsenic binding and removal in an ion flotation process.
Fatemeh Makavipour +2 more
doaj +1 more source
Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation [PDF]
, 2017 Oncogenic signaling in cancer cells alters glucose uptake and utilization to supply sufficient energy and biosynthetic intermediates for survival and sustained proliferation.
Hironori Katoh +7 more
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Advanced Science, EarlyView.This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang +10 more
wiley +1 more source
Inducing disulfidptosis in tumors:potential pathways and significance
MedCommRegulated cell death (RCD) is crucial for the elimination of abnormal cells. In recent years, strategies aimed at inducing RCD, particularly apoptosis, have become increasingly important in cancer therapy.
Tao Mi +4 more
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, 2019 © 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Appropriate dosing of cystine-binding thiol drugs in the management of cystinuria has been based on clinical stone activity. When new stones form, the dose is increased.
Mara, K. +5 more
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Advanced Science, EarlyView.ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source