Results 61 to 70 of about 90,075 (287)
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System x\u3csub\u3ec\u3c/sub\u3e\u3csup\u3e−\u3c/sup\u3e Mediates Aglycemic Neuronal Cell Death [PDF]
, 2015 The astrocyte cystine/glutamate antiporter (system xc−) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation. The purpose of this study was to determine the mechanism by which this occurred.
He, Yan +5 more
core +1 more source
Bis (2-pyrimidinyl) disulfide dihydrate: a redetermination [PDF]
, 2004 The crystal structure of bis(2-pyrimidinyl) disul®de dihydrate, C8H6N4S22H2O, has been redetermined using CCD diffractometer data. This has allowed for a more precise location of the water H atoms and shows the water molecules forming unusual spiral ...
Healy, Peter +4 more
core +2 more sources
Advanced Science, EarlyView.This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang +9 more
wiley +1 more source
Frontiers in MicrobiologyIntroductionAntibiotic overuse has caused the development of bacterial resistance, which is a major threat to public health. Intracellular metabolic processes are essential for maintaining the normal physiological activities of bacteria, and an ...
Junyuan Du +11 more
doaj +1 more source
p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells
Cell Reports, 2018 How cancer cells respond to nutrient deprivation remains poorly understood. In certain cancer cells, deprivation of cystine induces a non-apoptotic, iron-dependent form of cell death termed ferroptosis.
Amy Tarangelo +6 more
doaj +1 more source
Contents of Urinary System Stones in North Marmara Region and Their Distribution by Gender
Journal of Urological Surgery, 2020 Objective:We aimed to determine the contents of kidney stones in our country by evaluating the results of the stone analysis of patients who underwent surgery due to ureteral or kidney stones or experienced spontaneous stone expulsion.Materials and ...
Ekrem Güner, Kamil Gökhan Şeker
doaj +1 more source
Methionine synthesis in Neurospora. The isolation of cystathionine [PDF]
, 1947 Among artificially produced biochemical mutants of Neurospora, those which have lost the ability to synthesize methionine form the largest class. At the present writing 87 occurrences of the methionineless character have been observed in this laboratory ...
Horowitz, N. H.
core
The Effects of Cocaine on Different Redox Forms of Cysteine and Homocysteine, and on Labile, Reduced Sulfur in the Rat Plasma Following Active versus Passive Drug Injections [PDF]
, 2013 Received: 28 November 2012 / Revised: 19 April 2013 / Accepted: 6 May 2013 / Published online: 16 May 2013 The Author(s) 2013. This article is published with open access at Springerlink.comThe aim of the present studies was to evaluate cocaine ...
A Madayag +80 more
core +2 more sources
Advanced Science, EarlyView.FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang +11 more
wiley +1 more source