Results 31 to 40 of about 431 (97)

Dynamic membrane proteome of adipogenic and myogenic precursors in skeletal muscle highlights EPHA2 may promote myogenic differentiation through ERK signaling

The FASEB Journal, Volume 33, Issue 4, Page 5495-5509, April 2019., 2019
ABSTRACTThe balance of myogenic and adipogenic differentiation is crucial for skeletal muscle homeostasis. Given the vital role of membrane proteins (MBPs) in cell signal perception, membrane proteomics was conducted to delineate mechanisms regulating differentiation of adipogenic and myogenic precursors in skeletal muscle.
Xin Zhang, Liqi Wang, Kai Qiu, Doudou Xu, Jingdong Yin   +4 more
wiley   +1 more source

The Complement of Family M1 Aminopeptidases of Haemonchus Contortus - Biotechnological Implications

, 2016
Although substantial research has been focused on the ‘hidden antigen’ H11 of Haemonchus contortus as a vaccine against haemonchosis in small ruminants, little is know about this and related aminopeptidases.
Korhonen, Pasi K., Jabbar, Abdul, Koehler, Anson V, Gasser, Robin B., Mohandas, Namitha, Hofmann, Andreas, Young, Neil D., Hall, Ross S., Koehler, Anson V., Young, Neil D, Hall, Ross S, Hu, Min, Gasser, Robin B, Korhonen, Pasi K   +13 more
core   +2 more sources

Optimization of ultracentrifugation‐based method to enhance the purity and proteomic profiling depth of plasma‐derived extracellular vesicles and particles

Journal of Extracellular Biology, Volume 3, Issue 7, July 2024.
Abstract Circulating extracellular vesicles and particles (EVPs) are being investigated as potential biomarkers for early cancer detection, prognosis, and disease monitoring. However, the suboptimal purity of EVPs isolated from peripheral blood plasma has posed a challenge of in‐depth analysis of the EVP proteome. Here, we compared the effectiveness of
Zurong Wan, Jinghua Gu, Uthra Balaji, Linda Bojmar, Henrik Molina, Søren Heissel, Alexandra E. Pagano, Christopher Peralta, Lee Shaashua, Dorina Ismailgeci, Hope K. Narozniak, Yi Song, William R. Jarnagin, David P. Kelsen, Jaqueline Bromberg, Virginia Pascual, Haiying Zhang   +16 more
wiley   +1 more source

The Brain‐Heart Connection: Frontal Cortex and Left Ventricle Angiotensinase Activities in Control and Captopril‐Treated Hypertensive Rats—A Bilateral Study

International Journal of Hypertension, Volume 2013, Issue 1, 2013., 2013
The model of neurovisceral integration suggests that the frontal cortex (FC) and the cardiovascular function are reciprocally and asymmetrically connected. We analyzed several angiotensinase activities in the heart left ventricle (VT) of control and captopril‐treated SHR, and we search for a relationship between these activities and those determined in
Ana B. Segarra, Isabel Prieto, Inmaculada Banegas, Ana B. Villarejo, Rosemary Wangensteen, Marc de Gasparo, Francisco Vives, Manuel Ramírez-Sánchez, Patrick Vanderheyden   +8 more
wiley   +1 more source

Altered Peptidase Activities in Thyroid Neoplasia and Hyperplasia

Disease Markers, Volume 35, Issue 6, Page 825-832, 2013., 2013
Background. Papillary thyroid carcinoma (PTC), follicular thyroid adenoma (FTA), and thyroid nodular hyperplasia (TNH) are the most frequent diseases of the thyroid gland. Previous studies described the involvement of dipeptidyl‐peptidase IV (DPPIV/CD26) in the development of thyroid neoplasia and proposed it as an additional tool in the diagnosis ...
Gorka Larrinaga, Lorena Blanco, Peio Errarte, Maider Beitia, Begoña Sanz, Itxaro Perez, Amaia Irazusta, Clara E. Sánchez, Francisco Santaolalla, Leire Andrés, José I. López, Dinesh Kumbhare   +11 more
wiley   +1 more source

Human cord plasma proteomic analysis reveals sexually dimorphic proteins associated with intrauterine growth restriction

PROTEOMICS, Volume 24, Issue 7, April 2024.
Abstract Intrauterine growth restriction (IUGR) is associated with increased risk of cardiometabolic disease later in life and has been shown to affect female and male offspring differently, but the mechanisms remain unclear. The purpose of this study was to identify proteomic differences and metabolic risk markers in IUGR male and female neonates when
Ayodele Jacob Akinyemi, Xiu Quan Du, Jennifer Aguilan, Simone Sidoli, David Hirsch, Tao Wang, Sandra Reznik, Mamta Fuloria, Maureen J. Charron   +8 more
wiley   +1 more source

Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension

International Journal of Hypertension, Volume 2012, Issue 1, 2012., 2012
The classic renin‐angiotensin system (RAS) was initially described as a hormone system designed to mediate cardiovascular and body water regulation. The discovery of a brain RAS composed of the necessary functional components (angiotensinogen, peptidases, angiotensins, and specific receptor proteins) independent of the peripheral system significantly ...
John W. Wright, Shigehiko Mizutani, Joseph W. Harding, John R. Dietz   +3 more
wiley   +1 more source

Epidemiological evaluation of circulating levels of Copeptin and Fibronectin during pregnancy

, 2019
Submitted in fulfilment of the requirements for the degree of Masters in Technology: Environmental Health, Durban University of Technology, Durban, South Africa, 2019.Background: Despite efforts to reduce problems associated with child and maternal ...
Deepnarain, Kayshia
core   +1 more source

Validation of candidate genes from ChIP-seq via QT-PCR in STAT5A and STAT5B knock-down human CD4⁺ T cells.

, 2014
The expression levels were compared STAT5A KD or STAT5B KD CD4+ T cells with control CD4+ T cells. Genes regulated similarly by both STAT5A and STAT5B are SGK1, GTF2H5 and SLC22A5. Genes regulated specifically by STAT5A are NDRG1, DNAJC6, ST3GAL1, SAMD4A,
Arunima Kohli (114664), Trupti Kawli (183313), Rosa Bacchetta (481694), Kari C. Nadeau (114674), Michael Snyder (16695), Jennifer A. Jenks (517211), Takahiro Kanai (406131), Scott Seki (517210), Dorrelyn Patacsil Martin (517212)   +8 more
core   +1 more source

Investigation of LIX1 and its role in feline spinal muscular atrophy pathogenesis

, 2010
The spinal muscular atrophies (SMA) are a group of inherited disorders distinguished by proximal muscle weakness and atrophy due to spinal cord lower motor neuron degeneration.
Wakeling, Erin
core   +1 more source