Results 1 to 10 of about 87,362 (296)

Artesunate improves venetoclax plus cytarabine AML cell targeting by regulating the Noxa/Bim/Mcl-1/p-Chk1 axis

Cell Death and Disease, 2022
Venetoclax plus cytarabine therapy is approved for elderly acute myeloid leukemia (AML) patients and needs further improvement. We studied the mechanisms of venetoclax plus cytarabine treatment and searched for a third agent to enhance their effects ...
Jingyi Zhang, Yuetong Wang, Chujie Yin, Ping Gong, Zhenwei Zhang, Linxiang Zhao, Samuel Waxman, Yongkui Jing   +7 more
doaj   +2 more sources

Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study

Journal of Clinical Oncology, 2019
PURPOSE Effective treatment options are limited for patients with acute myeloid leukemia (AML) who cannot tolerate intensive chemotherapy. An international phase Ib/II study evaluated the safety and preliminary efficacy of venetoclax, a selective B-cell ...
Andrew H Wei, Walter Fiedler, Tara L Lin
exaly   +2 more sources

Cytarabine-Induced Encephalitis

Journal of the Belgian Society of Radiology, 2021
Teaching Point: Central nervous system adverse effects of cytarabine treatment include aseptic meningitis, myelopathy, and more rarely, encephalopathy, seizures, and cerebellar dysfunction.
Christine Lenfant, Nathalie Greiner, Thierry Duprez   +2 more
doaj   +7 more sources

CPX-351: a nanoscale liposomal co-formulation of daunorubicin and cytarabine with unique biodistribution and tumor cell uptake properties

International Journal of Nanomedicine, 2019
Lawrence D Mayer, Paul Tardi, Arthur C LouieJazz Pharmaceuticals, Inc., Palo Alto, CA, USAAbstract: Combination regimens are a standard of care for many cancers.
Mayer LD, Tardi P, Louie AC
doaj   +2 more sources

Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

New England Journal of Medicine, 2003
François Guilhot, Richard A Larson, Michele Baccarani   +2 more
exaly   +2 more sources

Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study

Lancet Oncology, The, 2020
Seth E Karol, Thomas B Alexander, Stanley B Pounds   +2 more
exaly   +2 more sources

Cytarabine syndrome revisited [PDF]

British Journal of Haematology, 2003
Wee Joo Chng
openalex   +4 more sources

Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the first randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial

Lancet Haematology,the, 2016
Andrés José Maria Ferreri, Kate Cwynarski, Maurilio Ponzoni   +2 more
exaly   +2 more sources

Effect of Rutin on Cytarabine-Associated Pulmonary Oedema and Oxidative Stress in Rats [PDF]

Anais da Academia Brasileira de Ciências, 2020
Cytarabine is effectively used in the treatment of adult acute leukemia, but it has a dose-limiting side effect of fatal pulmonary oedema because it increases the vascular permeability of the alveolar capillaries.
ASLI O. BILGIN, RENAD MAMMADOV, BAHADIR SULEYMAN, EDHEM UNVER, FATIH OZCICEK, MEHMET SOYTURK, FERDA K. CIMEN, NEZAHAT KURT, HALIS SULEYMAN   +8 more
doaj   +1 more source

Interaction of Lipophilic Cytarabine Derivatives with Biomembrane Model at the Air/Water Interface

Membranes, 2022
Cell membrane models are useful for obtaining molecular-level information on the interaction of biologically active molecules whose activity is believed to depend also on their effects on the membrane.
Jhon Fernando Berrio Escobar, Cristiano Giordani, Stefano Russo, Francesco Castelli, Maria Grazia Sarpietro   +4 more
doaj   +1 more source