Results 291 to 300 of about 100,040 (330)

Efficient One-Pot Synthesis of Cytidine 5'-Monophosphate Using an Extremophilic Enzyme Cascade System.

Journal of Agricultural and Food Chemistry, 2020
A rapid in vitro enzymatic biosynthesis system has been developed as a biological manufacturing platform with potential industrial uses. Cytidine 5'-monophosphate (5'-CMP) is a key intermediate in the preparation of several nucleotide derivatives and is ...
Zonglin Li, Xiao Ning, Yiran Zhao, Xiaodan Zhang, Chunmei Xiao, Zhimin Li   +5 more
semanticscholar   +1 more source

Activation-induced cytidine deaminase and active cytidine demethylation

Trends in Biochemical Sciences, 2015
The regulation of demethylation in vertebrates has begun to be elucidated in the past decade. However, a possible involvement of activation-induced cytidine deaminase (AID) in this process remains uncertain. We survey the data supporting or casting doubt on such a role, and propose that there is no strong evidence for an involvement of AID in genome ...
Almudena R, Ramiro, Vasco M, Barreto
openaire   +2 more sources

Cytidine Deaminase from Human Spleen

1989
No abstract ...
VITA, Alberto, Cacciamani, Tiziana, NATALINI, Paolo, RUGGIERI, Silverio, Magni, Giulio   +4 more
openaire   +3 more sources

Cytidine Deaminase in Human Lymphocytes

Nature New Biology, 1973
PERIPHERAL blood lymphocytes in culture undergo cell division in the presence of the mitogenic stimulant phyto-haemagglutinin (PHA)1. Some of the metabolic processes that occur shortly after stimulation include phosphorylation of membrane bound phosphatidyl inositol2, acetylation of histones3, changes in cyclic GMP levels4, a pronounced elevation of ...
C W, Abell, N W, Marchand
openaire   +2 more sources

Solvolyses of Cytosine and Cytidine

Journal of Pharmaceutical Sciences, 1972
It has been confirmed by UV spectrophotometry and TLC that cytosine and cytidine deaminate to uracil and uridine, respectively, at all pH values. These products slowly degrade further in strongly alkaline solutions. Cytidine also undergoes a parallel degradation in strongly alkaline solutions to a nonchromophoric compound, which can be assigned to a ...
E R, Garrett, J, Tsau
openaire   +2 more sources

Prebiotic Formation of Cytidine Nucleotides

Nature, 1971
IN contrast to the plausible explanations for proteinoid formation1, there seems to be no satisfactory concept for the genesis of polynucleotide templates in the presumed conditions of the primitive Earth. Only parts of the problem, such as the origin of the bases2,3 and carbohydrates4 and the synthesis of short oligonucleotides5,6, have been subjected
C M, Tapiero, J, Nagyvary
openaire   +2 more sources

Some dihydro-cytidines and -isocytidines

J. Chem. Soc., Perkin Trans. 1, 1974
Syntheses of 5,6-dihydrocytidine (IV), 5,6-dihydroisocytidine (V), and the 2-thioanalogue (VII) of the former are described. U.v. spectroscopic data for (V) and its 2-N-methyl and 2,2-di-N-methyl derivatives (IX) and (X) in alcoholic solution reveal amino rather than imino tautomeric states. The n.m.r.
V, Skarić, B, Gaspert, M, Hohnjec, G, Laćan   +3 more
openaire   +2 more sources

A ribozyme that lacks cytidine

Nature, 1999
The RNA-world hypothesis proposes that, before the advent of DNA and protein, life was based on RNA, with RNA serving as both the repository of genetic information and the chief agent of catalytic function. An argument against an RNA world is that the components of RNA lack the chemical diversity necessary to sustain life.
J, Rogers, G F, Joyce
openaire   +2 more sources

Fluorescent adenosine and cytidine derivatives

Biochemical and Biophysical Research Communications, 1972
Summary The reaction of chloroacetaldehyde with adenosine and cytidine produces a fluorescent product in each case. These products are easily distinguishable spectroscopically by their fluorescence emission maxima. Since the reaction is carried out in aqueous media under mild conditions of pH and temperature, it should prove extremely useful in ...
J R, Barrio, J A, Secrist, N J, Leonard
openaire   +2 more sources

A synthesis of ψ-cytidine

Carbohydrate Research, 1984
Abstract A practical, seven-step synthesis of 5-(β- d -ribofuranosyl)cytosine ( 1 , ψ-cytidine) was achieved. ψ-Uridine was converted into the 2′,3′-isopropylidene acetal 2 in 85% yield. Tosylation of 2 to the 5′-sulfonate 3 , followed by deacetonation, afforded 5′- O -tosyl-ψ-uridine ( 6 ) in good yield.
K W, Pankiewicz, K, Hirota, A, Matsuda, K A, Watanabe   +3 more
openaire   +2 more sources