Results 51 to 60 of about 6,252 (195)

Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]

open access: yes, 2010
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna   +10 more
core   +4 more sources

Surface antigens in Plasmodium falciparum malaria : PfEMP1 and SURFIN4.2 [PDF]

open access: yes, 2017
Plasmodium falciparum malaria is an infectious disease that on despite of the ongoing eradication efforts is still endemic in more than 100 countries, sometimes causing severe disease that leads to the death of around half a million people per year ...
Quintana Varon, Maria del Pilar
core   +1 more source

Precise Similarity of Many Human Proteins to Proteins of Prokarya [PDF]

open access: yes, 2007
Proteins originated in early forms of life and have long survived, because they have always been required. Some recognizably similar proteins are found in all sequence comparisons between species, no matter how distant, including prokaryotes and ...
Roy Britten
core   +2 more sources

A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformability [PDF]

open access: yes, 2016
Infection with the apicomplexan parasite Plasmodium falciparum is a major cause of morbidity and mortality worldwide. One of the Striking features of this parasite is its ability to remodel and decrease the deformability of host red blood cells, a ...
Brown, Christopher L.   +12 more
core   +1 more source

Oxidative Stress and Modification of Renal Vascular Permeability Are Associated with Acute Kidney Injury during P. berghei ANKA Infection [PDF]

open access: yes, 2012
Malaria associated-acute kidney injury (AKI) is associated with 45% of mortality in adult patients hospitalized with severe form of the disease. However, the causes that lead to a framework of malaria-associated AKI are still poorly characterized.
Barboza, Renato   +18 more
core   +1 more source

Epistatic Interactions Among Co‐Inherited Malaria‐Protective Red Blood Cell Polymorphisms and Their Effects Across the Infection‐Mortality Spectrum in Endemic Populations: A Systematic Review

open access: yesAnemia, Volume 2026, Issue 1, 2026.
Background Malaria remains a major global health burden, with red blood cell (RBC) polymorphisms conferring partial protection. However, the epistatic interactions among co‐inherited RBC polymorphisms are poorly understood. We aimed to characterise how epistatic interactions among malaria‐protective RBC polymorphisms modify risk across the infection‐to‐
George Paasi   +11 more
wiley   +1 more source

N-Terminal Segment of TvCyP2 Cyclophilin from Trichomonas vaginalis Is Involved in Self-Association, Membrane Interaction, and Subcellular Localization

open access: yesBiomolecules, 2020
In Trichomonas vaginalis (T. vaginalis), cyclophilins play a vital role in dislodging Myb proteins from the membrane compartment and leading them to nuclear translocation. We previously reported that TvCyP1 cyclophilin from T. vaginalis forms a dimer and
Sarita Aryal   +6 more
doaj   +1 more source

Prevalence and Clinical Impacts of Canine Herpesvirus‐1 (CHV‐1) in Dogs: A Review of Reproductive Effects and Ocular Lesions

open access: yesVeterinary Medicine and Science, Volume 11, Issue 6, November 2025.
Taxonomy: Herpesviridae, Alphaherpesvirinae and Varicellovirus. Diagnosis: PCR for genetic detection. Transmission: Birth, venereal and transplacental. Pathogenesis: Ocular lesions; blepharitis, conjunctivitis and ulcerative and non‐ulcerative keratitis.
Sina Soleimani   +4 more
wiley   +1 more source

Association between Endothelial Selectin (E-selectin) gene polymorphisms and E-selectin level with visceral leishmaniais, in an ARMS-PCR based study [PDF]

open access: yes, 2008
Background: In the visceral leishmaniasis (VL), parasites reside in reticuluendothelial system, mainly in macrophages. Endothelial Selectin (E-selectin) might play an important role in leukocyte-endothelium interactions and inflammatory cell recruitment.
Bazmani, A.   +4 more
core  

Severe malaria: what's new on the pathogenesis front? [PDF]

open access: yes, 2016
Plasmodium falciparum causes the most severe and fatal form of malaria in humans with over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of severe falciparum malaria, is often fatal and represents a major public ...
Grau, Georges Emile Raymond   +1 more
core   +1 more source

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