Results 1 to 10 of about 50,654 (294)

Cytochalasin B [PDF]

open access: bronzeThe Journal of Immunology, 1972
Abstract Cytochalasin B (2 to 4 µg/ml) reversibly inhibits the chemotactic response of human and rabbit polymorphonuclear leukocytes to a bacterial chemotactic factor or to the complement derived factor, C5a. At lower concentrations (1 to 0.1 µg/ml or less) Cytochalasin B actually stimulates chemotaxis.
Elmer L Becker   +3 more
  +4 more sources

Bioactive Phenylalanine Derivatives and Cytochalasins from the Soft Coral-Derived Fungus, Aspergillus elegans [PDF]

open access: goldMarine Drugs, 2013
One new phenylalanine derivative 4′-OMe-asperphenamate (1), along with one known phenylalanine derivative (2) and two new cytochalasins, aspochalasin A1 (3) and cytochalasin Z24 (4), as well as eight known cytochalasin analogues (5–12) were isolated from
Xue-Ping Sun   +8 more
doaj   +2 more sources

Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig [PDF]

open access: goldJournal of Physiological Sciences
Actin linked regulatory mechanisms are known to contribute contraction/relaxation in smooth muscle. In order to clarify whether modulation of polymerization/depolymerization of actin filaments affects relaxation process, we examined the effects of ...
Satoko Mihashi, Masaru Watanabe
doaj   +2 more sources

Cytochalasins from the Ash Endophytic Fungus Nemania diffusa DSM 116299 [PDF]

open access: yesMolecules
The secondary metabolome of Nemania diffusa, isolated as an ash endophytic fungus, was analyzed in detail. From its cultures, a previously undescribed cytochalasin 1 was isolated using preparative HPLC, together with six known congeners: 18-dehydroxy ...
Özge Demir   +4 more
doaj   +2 more sources

Dereplication of Cytochalasans and Octaketides in Cytotoxic Extracts of Endophytic Fungi from Casearia arborea (Salicaceae)

open access: yesMetabolites, 2022
Endophytes have been shown to be a source of novel drug prototypes. The Casearia genus is known for presenting cytotoxic clerodane diterpenes; however, there are few reports on secondary metabolites produced by its fungal microbiota. Thus, in the present
Augusto L. Santos   +7 more
doaj   +1 more source

Effect of age and cytoskeletal elements on the indentation-dependent mechanical properties of chondrocytes. [PDF]

open access: yes, 2013
Articular cartilage chondrocytes are responsible for the synthesis, maintenance, and turnover of the extracellular matrix, metabolic processes that contribute to the mechanical properties of these cells.
Blanchette, Craig   +5 more
core   +8 more sources

Testing Strategies of the In Vitro Micronucleus Assay for the Genotoxicity Assessment of Nanomaterials in BEAS-2B Cells

open access: yesNanomaterials, 2021
The evaluation of the frequency of micronuclei (MN) is a broadly utilised approach in in vitro toxicity testing. Nevertheless, the specific properties of nanomaterials (NMs) give rise to concerns regarding the optimal methodological variants of the MN ...
Tereza Cervena   +7 more
doaj   +1 more source

Bacterial Engulfment Mechanism Is Strongly Conserved in Evolution Between Earthworm and Human Immune Cells

open access: yesFrontiers in Immunology, 2021
Invertebrates, including earthworms, are applied to study the evolutionarily conserved cellular immune processes. Earthworm immunocytes (so-called coelomocytes) are functionally similar to vertebrate myeloid cells and form the first line of defense ...
Bohdana Kokhanyuk   +5 more
doaj   +1 more source

Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle

open access: yesJournal of Pharmacological Sciences, 2020
The role of cytoskeleton dynamics in the oxidative stress toward human vasculature has been unclear. The current study examined whether the cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial
Kazumi Takaishi   +5 more
doaj   +1 more source

Reversibility of cell surface label rearrangement [PDF]

open access: yes, 1976
Cell surface labeling can cause rearrangements of randomly distributed membrane components. Removal of the label bound to the cell surface allows the membrane components to return to their original random distribution, demonstrating that label is ...
Brown, Susan Smith, Revel, Jean-Paul
core   +1 more source

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