Results 41 to 50 of about 50,654 (294)
Differences in protein mobility between pioneer versus follower growth cones [PDF]
, 2007 Navigating growth cones need to integrate, process and respond to guidance signals, requiring dynamic information transfer within and between different compartments.
Bak +25 more
core +3 more sources
Current Issues in Molecular Biology, 2022 To date, there are numerous protocols for the isolation of extracellular vesicles (EVs). Depending on the isolation method, it is possible to obtain vesicles with different characteristics, enriched with specific groups of proteins, DNA and RNA, which ...
Zarema Gilazieva +6 more
doaj +1 more source
Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]
, 1994 . Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard +3 more
core +3 more sources
Advanced Science, EarlyView.TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu +7 more
wiley +1 more source
Strain-dependent porcine circovirus type 2 (PCV2) entry and replication in T-lymphoblasts [PDF]
, 2019 Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied.
Nauwynck, Hans +2 more
core +1 more source
Advanced Science, EarlyView.Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen +8 more
wiley +1 more source
Cell contractile force measured using a deformable hollow capsule
The EuroBiotech Journal, 2022 There are several possible ways to measure the contraction of cells in vitro. Here, we report measurements of the contractile properties of 3T3-L1 cells grown to confluence on 3D hollow capsules.
Ting Julia Ho Yee, Martin Donald K
doaj +1 more source
A permeabilized cell model for studying cytokinesis using mammalian tissue culture cells. [PDF]
, 1980 PtK1 cells lysed late in cell division in a medium containing the nonionic detergent Brij 58 and polyethylene glycol with continue to undergo cleavage after lysis.
CANDE, W. Zacheus
core
The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape [PDF]
, 2010 Phagocytosis is the fundamental cellular process by which eukaryotic cells bind and engulf particles by their cell membrane. Particle engulfment involves particle recognition by cell-surface receptors, signaling and remodeling of the actin cytoskeleton ...
Dart, Anna E. +3 more
core +4 more sources
Advanced Science, EarlyView.Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li +19 more
wiley +1 more source