Results 61 to 70 of about 48,300 (266)

Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle

Journal of Pharmacological Sciences, 2020
The role of cytoskeleton dynamics in the oxidative stress toward human vasculature has been unclear. The current study examined whether the cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial
Kazumi Takaishi, Hiroyuki Kinoshita, Guo-Gang Feng, Toshiharu Azma, Shinji Kawahito, Hiroshi Kitahata   +5 more
doaj  

Influence of Microalgae Planktochlorella nurekis Clones on Seed Germination

Agronomy, 2022
Microalgae are a rich source of plant hormones, vitamins, and other substances that can influence plant physiological metabolism, which in turn affects plant development, biotic and abiotic stress resistance, and yield.
Małgorzata Karbarz, Magdalena Piziak, Janusz Żuczek, Magdalena Duda   +3 more
doaj   +1 more source

Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by caco-2 cells - towards oral insulin [PDF]

, 2011
“The original publication is available at www.springerlink.com”. Copyright SpringerPurpose: The influence of polymer architecture on cellular uptake and transport across Caco-2 cells of novel amphiphilic polyelectrolyte-insulin nanocomplexes was ...
A Bayat, A Jintapattanakit, A Lin, AF Kotzé, AF Kotzé, AF Kotzé, AF Kotzé, Alastair McKinnon, AMM Sadeghi, CJ Thompson, CJ Thompson, CJ Thompson, CM Lehr, CM Lehr, Colin Thompson, F Qian, G Ranaldi, Gillian Smith, H Gersdorff von, IM Lubben van der, JH Hamman, JJH Chu, JP Bai, Karen Skene, KS Soppimath, L Yin, M Bendayan, M Mahkam, M Simon, M Simon, M Thanou, M-K Kim, Mhairi Smith, MM Thanou, N Nishiyama, NJ Kavimandan, P Artursson, Pramod Gadad, PS Pourhosseini, Rachel Knott, RJ Schilling, S Mao, S Sakuma, T Jung, Woei Ping Cheng, X Boulenc, Y-Y Huang   +46 more
core   +1 more source

UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification

Advanced Science, EarlyView.
Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia, He Zhang, Dingqiang Mo, Bo Xie, Hongdou Qiao, Tao Chen, Haoyue Song, Xinxin Xu, Sheng Yang   +8 more
wiley   +1 more source

A pharmacological cocktail for arresting actin dynamics in living cells. [PDF]

, 2011
The actin cytoskeleton is regulated by factors that influence polymer assembly, disassembly, and network rearrangement. Drugs that inhibit these events have been used to test the role of actin dynamics in a wide range of cellular processes.
Peng, Grace E, Weiner, Orion D, Wilson, Sarah R   +2 more
core   +2 more sources

Construction of Active Sites‐Accessible Au8 Clusters for Intensive Tumor Pyroptosis

Aggregate, EarlyView.
Ethynylferrocene (EFc) was utilized to engineer molecular‐like gold nanoclusters (NCs) with accessibly catalytic centers, resulting in NCs exhibiting excellent peroxidase‐like activity and the ability to radiosensitize, leading to the production of intracellular oxidative stress and activation of pyroptosis.
Qiu‐Xu Zang, Wei‐Tong Chen, Wenjing Zhang, Zhao‐Yang Wang, Xi‐Yan Dong, Runping Han, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig

Journal of Physiological Sciences
Actin linked regulatory mechanisms are known to contribute contraction/relaxation in smooth muscle. In order to clarify whether modulation of polymerization/depolymerization of actin filaments affects relaxation process, we examined the effects of ...
Satoko Mihashi, Masaru Watanabe
doaj   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering. [PDF]

PLoS ONE, 2016
Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise to a vast array of complex bioactive molecules with further complexity added by the existence of natural PKS-NRPS fusions.
Maria Lund Nielsen, Thomas Isbrandt, Lene Maj Petersen, Uffe Hasbro Mortensen, Mikael Rørdam Andersen, Jakob Blæsbjerg Hoof, Thomas Ostenfeld Larsen   +6 more
doaj   +1 more source

Actin-dependent cell elongation in teleost retinal rods: requirement for actin filament assembly. [PDF]

, 1981
Teleost retinal rods elongate when exposed to light. Elongation is mediated by a narrow necklike region called the myoid. In the cichlid Sarotherodon mossambicus, the rod inner segment (composed of the myoid with adjacent ellipsoid) increases in length ...
BURNSIDE, Beth, OConnor, P
core   +1 more source