Results 81 to 90 of about 50,654 (294)

Adult skeletal muscle stem cell migration is mediated by a blebbing/amoeboid mechanism [PDF]

, 2011
Adult skeletal muscle possesses a resident stem cell population called satellite cells which are responsible for tissue repair following damage. Satellite cell migration is crucial in promoting rapid tissue regeneration but is a poorly understood ...
Collins-Hooper, Henry, Dash, Philip R., Otto, Anthony, Patel, Anand, Patel, Ketan   +4 more
core   +1 more source

Rutaceae Zanthoxylum–Derived 7‐Demethylsuberosin Alleviates the Rheumatoid Arthritis Through Inhibiting the Maturation of Dendritic Cells via Targeting MAPK14 Functional Food‐Based 7‐Demethylsuberosin

Food Frontiers, EarlyView.
This study revealed that 7‐demethylsuberosin exhibits immunosuppressive effects both in vivo and in vitro. Furthermore, it inhibits the phosphorylation of MAPK14 by targeting it, thereby modulating dendritic cell (DC) maturation and function and reducing inflammation across various in vivo models.
Peng Han, Bo Wang, Luyang Han, Yanbo Zhu, Jiawei Dong, Yuekang Xu, Xiaoying Liu, Jinyao Li   +7 more
wiley   +1 more source

Membrane repair against H. pylori promotes cancer cell proliferation [PDF]

, 2010
Membrane repair is a universal response against physical and biological insults and enables cell survival. Helicobacter pylori is one of the most common human pathogens and the first formally recognized bacterial carcinogen associated with gastric cancer.
Chiung-Nien Chen, Hsuan-Cheng Huang, Hsueh-Fen Juan, Jin-Town Wang, Li-Ling Lin, Satoshi Ogihara   +5 more
core   +1 more source

Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia

Scientific Reports, 2017
It is well documented that microgravity in space environment leads to bone loss in astronauts. These physiological changes have also been validated by human and animal studies and modeled in cell-based analogs.
Wengui Shi, Yanfang Xie, Jinpeng He, Jian Zhou, Yuhai Gao, Wenjun Wei, Nan Ding, Huiping Ma, Cory J. Xian, Keming Chen, Jufang Wang   +10 more
doaj   +1 more source

An NMR Analysis of 10-Indol Cytochalasin Chaetoglobosin F

Chinese Journal of Magnetic Resonance, 2019
Cytochalasins are a group of natural products from fungus, and have been attracting lots of research interests in the field of microbiology. Cytochalasins possess complex and diverse structures, making nuclear magnetic resonance (NMR) based structure ...
YIN Tian-peng, WANG Ze, CHEN Yang, SHAO Ya-ting, DENG Liang, LI Wei   +5 more
doaj   +1 more source

Slowly cycling Rho kinase-dependent actomyosin cross-bridge slippage explains intrinsic high compliance of detrusor smooth muscle [PDF]

, 2017
Biological soft tissues are viscoelastic because they display timeindependent pseudoelasticity and time-dependent viscosity. However, there is evidence that the bladder may also display plasticity, defined as an increase in strain that is unrecoverable ...
Hurley, Tanner, Klausner, Adam P., Lin, Jia B., Miner, Amy S., Neal, Christopher J., Ratz, Paul H., Speich, John E.   +6 more
core   +2 more sources

Evidence for Drop‐Like Nuclear Deformation in Sheared Endothelial Monolayers

Small, EarlyView.
Physiological shear stress smoothens endothelial monolayers by selectively eliminating less‐spread cells with tall, wrinkled nuclei. Nuclear volume and surface area remain constant, consistent with drop‐like deformation governed by geometric constraints.
Mohammad Mohajeri, Ting‐Ching Wang, Pooja Agarwal, Simran Kaur, Ankit Kumar, Richard B. Dickinson, Abhishek Jain, Tanmay P. Lele   +7 more
wiley   +1 more source

Study on Chemicals for Post-activation in Porcine Somatic Cell Nuclear Transfer

Journal of Animal Reproduction and Biotechnology, 2016
Since the first success of animal cloning, somatic cell nuclear transfer presented various ideas in many research areas such as regenerative medicine. However, SCNT embryos has poor survival rate. Therefore, numerous researches carried out to enhance the
Kyuhong Min, Seungwon Na, Euncheol Lee, Ghangyong Kim, Youngkwang Yu, Pantu Kumar Roy, Xun Fang, MB Salih, Jongki Cho   +8 more
doaj   +1 more source

ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. [PDF]

, 2015
Backgrounds and aims4-6 million people die of enteric infections each year. After invading intestinal epithelial cells, enteric bacteria encounter phagocytes.
Casanova, James E, Castillo, Victoria, Choudhury, Sarmistha Sinha, Das, Soumita, Eckmann, Lars, Elliott, Michael R, Ernst, Peter B, Fox, Sarah, Owen, Katherine A, Sarkar, Arup   +9 more
core  

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source