Cytochalasin B Modulates Nanomechanical Patterning and Fate in Human Adipose-Derived Stem Cells [PDF]
Cells, 2022 Cytoskeletal proteins provide architectural and signaling cues within cells. They are able to reorganize themselves in response to mechanical forces, converting the stimuli received into specific cellular responses. Thus, the cytoskeleton influences cell
Eva Bianconi +12 more
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Angiogenic Activity of Cytochalasin B-Induced Membrane Vesicles of Human Mesenchymal Stem Cells [PDF]
Cells, 2019 The cytochalasin B-induced membrane vesicles (CIMVs) are suggested to be used as a vehicle for the delivery of therapeutics. However, the angiogenic activity and therapeutic potential of human mesenchymal stem/stromal cells (MSCs) derived CIMVs (CIMVs ...
Marina O. Gomzikova +10 more
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Distinctive Effects of Cytochalasin B in Chick Primary Myoblasts and Fibroblasts. [PDF]
PLoS ONE, 2016 Actin-based structures play fundamental roles in cellular functions. However it remains controversial how cells cope with the absence of F-actin structures.
Koichi Ojima +4 more
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The Journal of Immunology, 1972 Abstract Cytochalasin B (2 to 4 µg/ml) reversibly inhibits the chemotactic response of human and rabbit polymorphonuclear leukocytes to a bacterial chemotactic factor or to the complement derived factor, C5a. At lower concentrations (1 to 0.1 µg/ml or less) Cytochalasin B actually stimulates chemotaxis.
Elmer L Becker +3 more
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Increased Yield of Extracellular Vesicles after Cytochalasin B Treatment and Vortexing [PDF]
Current Issues in Molecular Biology, 2023 Extracellular vesicles (EVs) are promising therapeutic instruments and vectors for therapeutics delivery. In order to increase the yield of EVs, a method of inducing EVs release using cytochalasin B is being actively developed.
Sirina V. Kurbangaleeva +6 more
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Storage stability and delivery potential of cytochalasin B induced membrane vesicles [PDF]
Biotechnology Reports, 2021 Cell-free therapies based on extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) are considered as a promising tool for stimulating regeneration and immunomodulation. The need to develop a practical approach for large-scale production
Sevindzh K. Kletukhina +7 more
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Comparative Analysis of Natural and Cytochalasin B-Induced Membrane Vesicles from Tumor Cells and Mesenchymal Stem Cells [PDF]
Current Issues in Molecular Biology, 2022 To date, there are numerous protocols for the isolation of extracellular vesicles (EVs). Depending on the isolation method, it is possible to obtain vesicles with different characteristics, enriched with specific groups of proteins, DNA and RNA, which ...
Zarema Gilazieva +6 more
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In vitro micronucleus assay: Method for assessment of nanomaterials using cytochalasin B [PDF]
Frontiers in Toxicology, 2023 The in vitro micronucleus (MNvit) assay is used to evaluate the aneugenic and clastogenic potential of a test material based upon its ability to induce micronuclei in the cells.
Christopher S. Farabaugh +3 more
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Preparation, In Vivo Administration, Dose-Limiting Toxicities, and Antineoplastic Activity of Cytochalasin B [PDF]
Translational Oncology, 2015 An effective and inexpensive protocol for producing cytochalasins A and B is being disclosed to propose a viable method by which to examine the in vivo antineoplastic activity of these congeners in preclinical tumor-bearing mammalian models. In addition,
Matthew Trendowski +4 more
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Cytochalasin-B-Inducible Nanovesicle Mimics of Natural Extracellular Vesicles That Are Capable of Nucleic Acid Transfer [PDF]
Micromachines, 2019 Extracellular vesicles provide cell-to-cell communication and have great potential for use as therapeutic carriers. This study was aimed at the development of an extracellular vesicle-based system for nucleic acid delivery.
Anastasiya Oshchepkova +7 more
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