Results 91 to 100 of about 25,429 (197)

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

open access: yesAdvanced Science, Volume 13, Issue 36, 29 June 2026.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou   +9 more
wiley   +1 more source

Interaction Between Actin and Microtubules During Plant Development

open access: yesCytoskeleton, Volume 83, Issue 6, Page 328-336, June 2026.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu   +3 more
wiley   +1 more source

Observations on the Effects of Cytochalasin B and Cytochalasin D on ADP- and Chymotrypsin-Treated Platelets

open access: yesExperimental Biology and Medicine, 1984
Cytochalasin B has been reported to inhibit fibrinogen binding and aggregation of rabbit platelets in response to ADP. The present study was designed to ascertain whether cytochalasins B and D inhibit aggregation by interfering with the exposure of fibrinogen receptors or more directly by inhibiting binding to available receptors.
openaire   +2 more sources

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

open access: yeseFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy   +7 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

open access: yesFood Biomacromolecules, Volume 3, Issue 2, Page 237-251, June 2026.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Dysregulation of Non‐Muscle Myosin IIA Assembly and Phosphorylation in S100A4 Null Mouse Lens

open access: yesJournal of Cellular Physiology, Volume 241, Issue 6, June 2026.
This study identifies S100A4 as a critical regulator of NMIIA assembly, phosphorylation, and actin cytoskeletal organization in the ocular lens. Loss of S100A4 disrupts lens fiber cell architecture and impairs lens transparency, revealing a previously unrecognized role for S100A4 in maintaining lens homeostasis and structural integrity.
Rupalatha Maddala   +3 more
wiley   +1 more source

Unravelling the impact of linear energy transfer on micronuclei induction from proton and photon irradiation

open access: yesScientific Reports
Micronucleus (MN) formation has a strong link to radiation damage and is a common bio-dosimeter for acute radiation exposures. The percentage of cells containing MN (PCMN) has a strong relationship with dose, however variation between previous studies ...
Charlotte J. Heaven   +8 more
doaj   +1 more source

Cell Membrane Vesicles Encapsulating Il24 mRNA With Enriched CD6 Display Exhibit Enhanced Targeted Antitumor Efficacy

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT mRNA‐based therapeutics offer significant potential for cancer treatment owing to their ability to induce transient, non‐integrating expression of therapeutic proteins. However, effective and tumour‐specific delivery remains a major barrier.
Dandan Wang   +8 more
wiley   +1 more source

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