Results 81 to 90 of about 25,429 (197)
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li +6 more
wiley +1 more source
Effects of Cytochalasin B On Mammalian Melanocytes and Keratinocytes
A study was carried out on the in vitro effects cytochalasin B on melanocytes and keratinocytes obtained from guinea pig skin. Observations of cell cultures made with time-lapse cinematography and electron microscopy show that cytochalasin produces marked changes in cell morphology.
Wikswo, Muriel A., Szabo, George
openaire +2 more sources
Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu +7 more
wiley +1 more source
New Cadinane Sesquiterpenes from the Stems of Kadsura heteroclita
As part of our continual efforts to exploit ‘Tujia Ethnomedicine’ for their pharmacophoric functionalities, we herein investigated Kadsura heteroclita collected from a deep Wulin mountain area in northern Hunan province.
Liang Cao +11 more
doaj +1 more source
Actuation of Cell Layers in Three Dimensions
ABSTRACT The alignment of fibers and cells in living tissues affect their mechanical properties and functionality. In this context, one can draw an analogy between tissues and nematic liquid crystal elastomers. We explore this analogy by growing fibroblasts on 2D‐patterned substrates and observing the contraction of cell sheets upon detachment from the
Kirsten Endresen +6 more
wiley +1 more source
Limited T-Cell-Stimulating Effect of Cytochalasin-B-Induced Membrane Vesicles Isolated from Artificial Antigen-Presenting Cells. [PDF]
Kim Y +5 more
europepmc +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Cytochalasin B reacts with thiols [PDF]
Lienhard, Gustav E. +1 more
openaire +2 more sources
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model. [PDF]
Chulpanova DS +6 more
europepmc +1 more source

