Results 111 to 120 of about 46,080 (279)

Shiga toxin production and translocation during microaerobic human colonic infection with Shiga toxin-producing E. coli O157:H7 and O104:H4 [PDF]

, 2014
Haemolytic uraemic syndrome caused by Shiga toxin-producing E. coli (STEC) is dependent on release of Shiga toxins (Stxs) during intestinal infection and subsequent absorption into the bloodstream.
Billoud, Lucile, Lewis, Steven B., Phillips, Alan D., Schüller, Stephanie, Tran, Seav-ly   +4 more
core   +2 more sources

Galactomyces ferment filtrate upregulates anchoring junctions and stabilizes actin to maintain the Young's modulus of skin cells in vitro

International Journal of Cosmetic Science, EarlyView.
Ageing causes actin cytoskeleton disorganization, a reduction in cellular components associated with the actin cytoskeleton and focal adhesions, and a reduction in skin firmness. Galactomyces ferment filtrate boosts actin stability, increases expression of anchoring junction proteins, including focal adhesions and protects against loss of firmness ...
Steph Crabtree, Bradley B. Jarrold, Olivia Kent, Matthew C. Ehrman, Timothy J. Hawkins, Viktor Korolchuk, Camila Pereira Braga, John M. Snowball, Makio Tamura, Tomohiro Hakozaki, Akira Matsubara, John E. Oblong, Max Brown   +12 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Traction force generation in Plasmodium sporozoites is modulated by a surface adhesin

Journal of Microscopy, EarlyView.
Abstract Plasmodium sporozoites are the highly polarised and motile forms of the malaria parasite transmitted by mosquitoes to the vertebrate hosts. Sporozoites use myosin motors to generate retrograde flow of actin filaments. These are linked to plasma membrane spanning adhesins, which in turn bind to the extracellular environment, resulting in ...
Johanna Ripp, Dimitri Probst, Mirko Singer, Ulrich S. Schwarz, Friedrich Frischknecht   +4 more
wiley   +1 more source

Microcondensate‐Mediated Intracellular Infusion of mRNA Across the Plasma Membrane

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
The delivery of mRNA without lipid nanoparticles remains challenging. FcB(L17E)3‐driven microcondensates with nucleic acids, aided by short ssDNA, enable coacervate formation, actin‐dependent cytosolic infusion, and in vivo protein expression, offering a potential platform for next‐generation mRNA therapeutics and vaccination.
Yoshimasa Kawaguchi, Ayumi Kikkawa, Seigo Kimura, Hiroshi Abe, Shiroh Futaki   +4 more
wiley   +2 more sources

Briarenones A‒C, New Briarellin Diterpenoids from the Gorgonian Briareum violaceum

Marine Drugs, 2019
Three new eunicellin-derived diterpenoids of briarellin type, briarenones A‒C (1‒3), were isolated from a Formosan gorgonian Briareum violaceum. The chemical structures of the compounds were elucidated on the basis of extensive spectroscopic analyses ...
Yang Cheng, Atallah F. Ahmed, Raha S. Orfali, Chang-Feng Dai, Jyh-Horng Sheu   +4 more
doaj   +1 more source

Deciphering the biosynthetic pathways of lichen acids

New Phytologist, EarlyView.
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim, Tânia Keiko Shishido, Huong T. Pham, Kyo Bin Kang, Rundong Liu, Matti Wahlsten, Jérôme Collemare, Hyun Park, Soon‐Ok Oh, Hyung‐Ho Ha, Hangun Kim, Jae‐Seoun Hur   +11 more
wiley   +1 more source

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

Molecular Oral Microbiology, EarlyView.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes, Travis J. Chiarelli, Doaa N. Abdallah, Grayson Way, Huiping Zhou, Jason A. Carlyon, Daniel P. Miller   +6 more
wiley   +1 more source

Cytochalasin B Influences Cytoskeletal Organization and Osteogenic Potential of Human Wharton's Jelly Mesenchymal Stem Cells. [PDF]

Pharmaceuticals (Basel), 2023
Pampanella L, Abruzzo PM, Tassinari R, Alessandrini A, Petrocelli G, Ragazzini G, Cavallini C, Pizzuti V, Collura N, Canaider S, Facchin F, Ventura C.   +11 more
europepmc   +1 more source

Microfilamentous system and secretion of enzyme in the exocrine pancreas. Effect of cytochalasin B. [PDF]

, 1975
H Bauduin, Christiane Stock, D Vincent, J.F. Grenier   +3 more
openalex   +1 more source