Results 21 to 30 of about 46,080 (279)

Resolution of the Hypoxylon fuscum Complex (Hypoxylaceae, Xylariales) and Discovery and Biological Characterization of Two of Its Prominent Secondary Metabolites

Journal of Fungi, 2021
Hypoxylon, a large, cosmopolitan genus of Ascomycota is in the focus of our current poly-thetic taxonomic studies, and served as an excellent source for bioactive secondary metabolites at the same time. The present work concerns a survey of the Hypoxylon
Christopher Lambert, Mohammad Javad Pourmoghaddam, Marjorie Cedeño-Sanchez, Frank Surup, Seyed Akbar Khodaparast, Irmgard Krisai-Greilhuber, Hermann Voglmayr, Theresia E. B. Stradal, Marc Stadler   +8 more
doaj   +1 more source

Bacterial Engulfment Mechanism Is Strongly Conserved in Evolution Between Earthworm and Human Immune Cells

Frontiers in Immunology, 2021
Invertebrates, including earthworms, are applied to study the evolutionarily conserved cellular immune processes. Earthworm immunocytes (so-called coelomocytes) are functionally similar to vertebrate myeloid cells and form the first line of defense ...
Bohdana Kokhanyuk, Kornélia Bodó, György Sétáló Jr, György Sétáló Jr, Péter Németh, Péter Engelmann   +5 more
doaj   +1 more source

Effect of age and cytoskeletal elements on the indentation-dependent mechanical properties of chondrocytes. [PDF]

, 2013
Articular cartilage chondrocytes are responsible for the synthesis, maintenance, and turnover of the extracellular matrix, metabolic processes that contribute to the mechanical properties of these cells.
Blanchette, Craig, Chahine, Nadeen O, Haudenschild, Dominik, Loots, Gabriela G, Lu, Jeffrey, Thomas, Cynthia B   +5 more
core   +8 more sources

Quantitative Analysis of the Cytoskeleton’s Role in Inward Rectifier KIR2.1 Forward and Backward Trafficking

Frontiers in Physiology, 2022
Alteration of the inward rectifier current IK1, carried by KIR2.1 channels, affects action potential duration, impacts resting membrane stability and associates with cardiac arrhythmias.
Encan Li, Vera Loen, Willem B. van Ham, Willy Kool, Marcel A. G. van der Heyden, Hiroki Takanari   +5 more
doaj   +1 more source

Recovery of aging-related size increase of skin epithelial cells: in vivo mouse and in vitro human study. [PDF]

PLoS ONE, 2015
The size increase of skin epithelial cells during aging is well-known. Here we demonstrate that treatment of aging cells with cytochalasin B substantially decreases cell size.
Igor Sokolov, Natali V Guz, Swaminathan Iyer, Amy Hewitt, Nina A Sokolov, Joseph S Erlichman, Craig D Woodworth   +6 more
doaj   +1 more source

Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle

Journal of Pharmacological Sciences, 2020
The role of cytoskeleton dynamics in the oxidative stress toward human vasculature has been unclear. The current study examined whether the cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial
Kazumi Takaishi, Hiroyuki Kinoshita, Guo-Gang Feng, Toshiharu Azma, Shinji Kawahito, Hiroshi Kitahata   +5 more
doaj   +1 more source

Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation

Journal of Fungi, 2022
Laying the groundwork on preliminary structure–activity relationship study relating to the disruptive activity of cytochalasan derivatives on mammalian cell actin cytoskeleton, we furthered our study on the cytochalasans of the Dothideomycetes fungus ...
Katherine Yasmin M. Garcia, Mark Tristan J. Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia E. B. Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler, Frank Surup, Allan Patrick G. Macabeo   +11 more
doaj   +1 more source

Reversibility of cell surface label rearrangement [PDF]

, 1976
Cell surface labeling can cause rearrangements of randomly distributed membrane components. Removal of the label bound to the cell surface allows the membrane components to return to their original random distribution, demonstrating that label is ...
Brown, Susan Smith, Revel, Jean-Paul
core   +1 more source

Myosin V and iNOS expression is enhanced in J774 murine macrophages treated with IFN-gamma [PDF]

Brazilian Journal of Medical and Biological Research, 2001
Actin-based motor protein requirements and nitric oxide (NO) production are important features of macrophage activity during phagocytosis or microbicidal processes.
D.S. Reis, M.A. Souza, J.R. Mineo, F.S. Espindola   +3 more
doaj   +1 more source

A proanthocyanidin from cinnamomum zeylanicum stimulates phosphorylation of insulin receptor in 3t3-l1 adipocytes [PDF]

, 2006
Non-insulin-dependent diabetes mellitus is due to in large part to insulin resistance, a state where the target cells are no longer responding to ordinary levels of circulating insulin.
Abdul Majid, Fadzilah Adibah, Sarmidi, Mohamad Roji, Taher, Muhammad   +2 more
core   +1 more source