Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin [PDF]
Mediators of Inflammation, 2017 Neutrophils play an essential role in innate immunity due to their ability to migrate into infected tissues and kill microbes with bactericides located in their secretory granules.
Svetlana I. Galkina +6 more
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The influence of actin depolymerization induced by Cytochalasin D and mechanical stretch on interleukin-8 expression and JNK phosphorylation levels in human retinal pigment epithelial cells [PDF]
BMC Ophthalmology, 2017 Background This study explores the role of actin cytoskeleton depolymerization induced by Cytochalasin D and mechanical stretch on the interleukin-8 (IL-8) expression and c-jun N-terminal kinase (JNK) phosphorylation levels in human retinal pigment ...
Meng Gao +8 more
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Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way. [PDF]
Exp Mol Med, 2012 Actin cytoskeleton has been known to control and/or be associated with chondrogenesis. Staurosporine and cytochalasin D modulate actin cytoskeleton and affect chondrogenesis.
Kim M, Song K, Jin EJ, Sonn J.
europepmc +4 more sources
Action of cytochalasin D on cytoskeletal networks. [PDF]
The Journal of cell biology, 1982 Extraction of SC-1 cells (African green monkey kidney) with the detergent Triton X-100 in combination with stereo high-voltage electron microscopy of whole mount preparations has been used as an approach to determine the mode of action of cytochalasin D ...
Manfred Schliwa
semanticscholar +6 more sources
Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig [PDF]
Journal of Physiological SciencesActin linked regulatory mechanisms are known to contribute contraction/relaxation in smooth muscle. In order to clarify whether modulation of polymerization/depolymerization of actin filaments affects relaxation process, we examined the effects of ...
Satoko Mihashi, Masaru Watanabe
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Crystal structures of monomeric actin bound to cytochalasin D. [PDF]
J Mol Biol, 2008 The fungal toxin cytochalasin D (CD) interferes with the normal dynamics of the actin cytoskeleton by binding to the barbed end of actin filaments. Despite its widespread use as a tool for studying actin-mediated processes, the exact location and nature of its binding to actin have not been previously determined. Here we describe two crystal structures
Nair UB +5 more
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Binding of Cytochalasin D to Platelet and Muscle Myosin
Journal of Biological Chemistry, 1973 Abstract Human blood platelets exposed to 2 um tritiated cytochalasin D showed maximum incorporation within 5 min. Tritiated cytochalasin D was found to be bound to thrombosthenin M (platelet myosin), when subjected to gel exclusion chromatography in 0.6 m KCl.
Elena Puszkin +3 more
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Responses ofEuglena gracilisto Cytochalasins B and D. [PDF]
Bolletino di zoologia, 1979 Abstract Euglena gracilis was exposed to cytochalasins B and D, dissolved in dimethylsulfoxide (DMSO). Cytochalasin B had no effect on biological activities, such as growth rate, swimming speed and vacuolar contractions, whereas cytochalasin D affected both cell viability and vacuolar contractions. No effect whatsoever was observed on the step-down and
Olimpia Coppellotti +3 more
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ACTION OF CYTOCHALASIN D ON CELLS OF ESTABLISHED LINES [PDF]
The Journal of Cell Biology, 1974 Cells in culture exposed to cytochalasin D (CD) rapidly undergo a long-sustained tonic contraction. Coincident with this contracture the thin microfilaments of the cortex become compacted into feltlike masses.
A. Miranda, G. Godman, S. Tanenbaum
semanticscholar +9 more sources
Journal of Cell Biology, 1975 The projection of knobby protuberances at the cell surface (zeiosis) is a general cellular response to cytochalasin D (CD), resulting from herniation of endoplasm through undefended places of the cortex during cell contractions and displacement of ...
Gabriel C. Godman +3 more
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