Results 1 to 10 of about 24,776 (201)

The influence of actin depolymerization induced by Cytochalasin D and mechanical stretch on interleukin-8 expression and JNK phosphorylation levels in human retinal pigment epithelial cells [PDF]

open access: goldBMC Ophthalmology, 2017
Background This study explores the role of actin cytoskeleton depolymerization induced by Cytochalasin D and mechanical stretch on the interleukin-8 (IL-8) expression and c-jun N-terminal kinase (JNK) phosphorylation levels in human retinal pigment ...
Meng Gao   +8 more
doaj   +4 more sources

Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin [PDF]

open access: goldMediators of Inflammation, 2017
Neutrophils play an essential role in innate immunity due to their ability to migrate into infected tissues and kill microbes with bactericides located in their secretory granules.
Svetlana I. Galkina   +6 more
doaj   +4 more sources

Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig [PDF]

open access: yesJournal of Physiological Sciences
Actin linked regulatory mechanisms are known to contribute contraction/relaxation in smooth muscle. In order to clarify whether modulation of polymerization/depolymerization of actin filaments affects relaxation process, we examined the effects of ...
Satoko Mihashi, Masaru Watanabe
doaj   +2 more sources

Stimulatory effect of cytochalasin D on antigen-induced phospholipase D activation in a murine mast cell model (RBL-2H3)

open access: goldAllergology International, 1999
To investigate the possible involvement of cytoskeletal components in antigen (Ag)-mediated activation of phospholipase D (PLD) in rat basophilic leukemia (RBL-2H3) cells, the effects of cytochalasin D, which is known to interfere with actin organization
Yoshikatsu Nakamura   +6 more
doaj   +2 more sources

Zopfiellasins A–D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment [PDF]

open access: goldMolecules, 2021
In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp.
Jie-Yu Zhang   +4 more
doaj   +2 more sources

Unconventional semi-solid cultivation enhances cytochalasins production by the Colombian fungus Xylaria sp. CM-UDEA-H199 [PDF]

open access: yesBMC Biotechnology
Fungal species of the order Xylariales, particularly those from tropical and untapped areas like the Amazon region, denote an intriguing reservoir of biodiversity and chemically varied metabolites.
Daniela Valencia-Revelo   +8 more
doaj   +2 more sources

Bacterial Engulfment Mechanism Is Strongly Conserved in Evolution Between Earthworm and Human Immune Cells

open access: yesFrontiers in Immunology, 2021
Invertebrates, including earthworms, are applied to study the evolutionarily conserved cellular immune processes. Earthworm immunocytes (so-called coelomocytes) are functionally similar to vertebrate myeloid cells and form the first line of defense ...
Bohdana Kokhanyuk   +5 more
doaj   +1 more source

Cytoskeletal Remodeling Mimics Endothelial Response to Microgravity

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mechanical cues contribute to the maintenance of a healthy endothelium, which is essential for vascular integrity. Indeed endothelial cells are mechanosensors that integrate the forces in the form of biochemical signals.
Laura Locatelli   +2 more
doaj   +1 more source

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