Results 111 to 120 of about 15,288,548 (274)
The active transport of polypeptides in the rabbit nasal mucosa is supported by a specific vesicular transport inhibited by cytochalasin D [PDF]
, 1996 We have previously demonstrated that polypeptides (elcatonin and ACTH) can be actively absorbed across the rabbit nasal mucosa. In this paper we show that elcatonin is also transported when it is adsorbed onto microspheres (diameter: 0.5 μm), whereas the
Cremaschi, Dario +2 more
core +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
Small, EarlyView.The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho +10 more
wiley +1 more source
EFFECT OF COLLAGEN I GEL ON APOPTOSIS OF RAT HEPATIC STELLATE CELLS
Acta Medica, 2013 Activated hepatic stellate cells (HSC) are a major source of fibrous proteins in cirrhotic liver. Inducing or accelerating their apoptosis is a potential way of liver fibrosis treatment.
Lenka Bittnerová +4 more
doaj +1 more source
Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating. [PDF]
, 2018 L-type CaV1.2 channels are key regulators of gene expression, cell excitability and muscle contraction. CaV1.2 channels organize in clusters throughout the plasma membrane.
Brust-Mascher, Ingrid +8 more
core +2 more sources
The Dark Side of FIBTEM: Cytochalasin D [PDF]
Journal of Cardiothoracic and Vascular Anesthesia, 2020 Catherine Reid +2 more
openaire +3 more sources
Rejuvenation of Senescent Cells, In Vitro and In Vivo, by Low‐Frequency Ultrasound
Aging Cell, EarlyView.Optimized low‐frequency ultrasound rejuvenates induced senescent cells and aged mice. Our results show that LFU reverses 15 aspects of senescent cells including growth and revitalizes aged mice. ABSTRACT The presence of senescent cells causes age‐related pathologies since their removal by genetic or pharmacological means, as well as possibly by ...
Sanjay K. Kureel +8 more
wiley +1 more source
Opto-Electric Cellular Biosensor Using Optically Transparent Indium Tin Oxide (ITO) Electrodes
Sensors, 2008 Indium tin oxide (ITO) biosensors are used to perform simultaneous optical and electrical measurements in order to examine the dynamic cellular attachment, spreading, and proliferation of endothelial cells (ECs) as well as cytotoxic effects when exposed ...
Kenneth D. Kihm +5 more
doaj
Dynamic regulation of quaternary organization of the M1 muscarinic receptor by subtype-selective antagonist drugs [PDF]
, 2016 Although rhodopsin-like G protein-coupled receptors can exist as both monomers and non-covalently associated dimers/oligomers, the steady-state proportion of each form and whether this is regulated by receptor ligands is unknown.
Godin, Antoine G. +4 more
core +1 more source
Aging Cell, EarlyView.Direct activation and rejuvenation of aged fibroblasts through the application of mechanical forces in a 3D spheroid culture model. The ERK signaling pathway was revealed as a key underlying mechanism. ABSTRACT Age‐related changes in human dermal fibroblasts (HDFs) contribute to impaired wound healing and skin aging.
Hui Liu +4 more
wiley +1 more source
Cell Proliferation, EarlyView.Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang +23 more
wiley +1 more source