Results 111 to 120 of about 24,776 (201)

Biosafety Evaluation of 6,7‐Dihydroxy‐3‐(2‐Nitrophenyl)Coumarin in Human Cells

open access: yesJournal of Applied Toxicology, Volume 46, Issue 1, Page 198-206, January 2026.
ABSTRACT Coumarins are considered a privileged scaffold in medicinal chemistry, as they may interact with biological macromolecules, presenting several pharmacological properties. Their potential makes them an object of study for the evaluation of their safety for humans, which is essential in the design of a potential drug.
Júlia Zocca Nunes de Barros   +3 more
wiley   +1 more source

Macropinocytic Uptake and pH‐Responsive Endolysosomal Processing Drive Sustained Chemotherapeutic Efficacy of High‐Load Core@Shell Nanocarriers in Colorectal Cancer

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
This study develops core@shell nanocarriers with an exceptionally high chemotherapy drug payload, exhibiting strong cytotoxic effects. Using this adaptable nanocarrier‐synthesis platform, herein, the cellular uptake pathway and intracellular journey of the nanocarriers are elucidated with different probe‐based imaging strategies.
Dolma Choezom   +11 more
wiley   +1 more source

Cytochalasin B-sensitive 2-Deoxy-d-glucose Transport in Adipose Cell Ghosts

open access: hybrid, 1973
Michael Czech   +2 more
openalex   +1 more source

Multiwalled Carbon Nanotubes as Physical Drivers of Chromosome Instability and Inflammatory Responses

open access: yesSmall Structures, Volume 7, Issue 1, January 2026.
This article highlights the fibrous morphology of multiwalled carbon nanotubes as a key factor in their genotoxicity. Fibers physically interfere in cell division, generating binucleated cells and micronuclei, both of which are precursors of carcinogenesis.
Núria Pulido‐Artola   +4 more
wiley   +1 more source

Validation of Osteogenic Properties of Cytochalasin D by High-Resolution RNA-Sequencing in Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissues. [PDF]

open access: yesStem Cells Dev, 2018
Samsonraj RM   +9 more
europepmc   +1 more source

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