Results 91 to 100 of about 3,467 (213)

شاهدی بر وجود جريان پتاسيمی جبرانی تأخيری فوق سريع (IKur) در دو گره سينوسی- دهليزی و دهليزی- بطنی قلب موش صحرايی [PDF]

, 2008
زمينه: گره سينوسی-دهليزی مرکز فعاليت پيس ميکری اوليه قلب می باشد. اگر به هر دليلی، گره سينوسی-دهليزی فعاليت خود را از دست بدهد، گره دهليزی-بطنی فوراً شروع به تنظيم فعاليت های قلب می نمايد.
نیکمرام, محمرضا, یانی, ژوزف   +1 more
core  

Morphological Effects on Expression of Growth Differentiation Factor 15 (GDF15), a Marker of Metastasis [PDF]

, 2014
Cancer cells typically demonstrate altered morphology during the various stages of disease progression as well as metastasis. While much is known about how altered cell morphology in cancer is a result of genetic regulation, less is known about how ...
Allard, Bootcov, Brown, Bubb, Chen, Chen, Coleman, D'Addario, de Bono, DeMarzo, Desoize, Fincham, Friedl, Friedl, Gabriel, Geng, Ghods, Gleason, Hillmann, Hromas, Isaacs, Johnen, Kempf, Khan, Kluger, Lee, Lim, Lim, Liu, Liu, Marrinucci, McBeath, Morton, Mundy, Namiki, Proutski, Roth, Russo, Schedin, Selander, Shim, Shim, Soucek, Stott, Viguet-Carrin, Wakchoure, Wallin, Wang, Weaver, Webb, Wiklund, Zare-Mehrjardi, Zhao   +52 more
core   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Acetylcholine Receptors and Concanavalin A-Binding Sites on Cultured Xenopus Muscle Cells: Electrophoresis, Diffusion, and Aggregation [PDF]

, 1988
Using digitally analyzed fluorescence videomicroscopy, we have examined the behavior of acetylcholine receptors and concanavalin A binding sites in response to externally applied electric fields.
Fraser, Scott E., Stollberg, Jes
core  

Looking at cell mechanics with atomic force microscopy: Experiment and theory [PDF]

, 2014
This review reports on the use of the atomic force microscopy in the investigation of the mechanical properties of cells. It is shown that the technique is able to deliver information about the cell surface properties (e.g., topography), the Young ...
Alcaraz, Alessandrini, Almqvist, Arnoldi, Azeloglu, Benitez, Borkovec, Bornschlögl, Braunstein, Camesano, Costa, Costa, Crick, Cross, Cumpsen, Dhahri, Doktycz, Ducker, Fischel, Fisher, Florin, Gaboriaud, Garcia, Grimellec, Harris, Henderson, Hinterdorfer, Hobbs, Hoh, Hugel, Johnson, Ketene, Landingham, Longo, Lu, Luque, Maugis, Melzak, Melzak, Melzak, Mendez-Vilas, Moeendarbary, Moreno Flores, Moreno-Flores, Moreno-Flores, Mosier, Murphy, Pietuch, Puech, Putman, Radmacher, Radmacher, Radmacher, Raman, Riande, Rotsch, Saravia, Scheuring, Stewart, Style, Sunyer, Titushkin, Vadillo-Rodriguez, Vargas-Pinto, Varghese Chacko, Walter, Zelenskaya, Zimmer   +67 more
core   +1 more source

Cytosolic delivery of bacterial metabolites by riboflavin transporters promotes MR1 antigen presentation and MAIT cell recognition

Immunology &Cell Biology, EarlyView.
VitBAg antigen presentation is promoted through a cytosolic pathway that reaches ligand‐receptive MR1 to present to MAIT cells, like the riboflavin transport pathway. Riboflavin solute carrier transporters can promote this MR1 presentation, but they are not essential for this role, suggesting redundant pathways to uptake VitBAg.
Sebastian Cruz‐Gomez, Hui Jing Lim, Brunda Nijagal, Yuting Yang, Nicole Lau, Jeffrey YW Mak, David P Fairlie, Hayley Newton, Mariolina Salio, Jose A Villadangos, Hamish EG McWilliam   +10 more
wiley   +1 more source

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism [PDF]

, 2015
Inflammasomes are cytosolic caspase-1-activation complexes that sense intrinsic and extrinsic danger signals, and trigger inflammatory responses and pyroptotic cell death. Homotypic interactions among Pyrin domains and caspase recruitment domains (CARDs)
A Dorfleutner, A Druilhe, A Lu, A Lu, A Vezzani, Alexander B Tong, Alvin Lu, B Wu, C Stehlik, CP Guimaraes, E de Alba, E Latz, EF Pettersen, EH Egelman, EM Kofoed, EW Humke, F Bedoya, F DiMaio, F Hou, F Martinon, Florian I Schmidt, G López-Castejón, GG Brusselle, GR Robbins, H Hirakawa, H Wu, Hao Wu, HH Park, Hidde L Ploegh, HT Le, JA Cooper, JA Mindell, JE Caldwell, JP da Cunha, K Kersse, KL Meerbrey, KL Tsao, L Holm, L Zhang, M Aguilera, M Biasini, M Lamkanfi, M Lamkanfi, MD Winn, MF Carlier, N Esser, NA Maun, P Emsley, PD Adams, PM Ridker, Q Qiao, Qian Yin, R Ferrao, SC Lin, SH Lee, SH Scheres, Shuobing Chen, T Wakatsuki, Tian-Min Fu, TR Shaikh, X Cai, Y Qu, Yang Li, YH Lin, Youdong Mao, Z Hu   +65 more
core   +2 more sources

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

Molecular Oral Microbiology, Volume 41, Issue 3, Page 131-144, June 2026.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes, Travis J. Chiarelli, Doaa N. Abdallah, Grayson Way, Huiping Zhou, Jason A. Carlyon, Daniel P. Miller   +6 more
wiley   +1 more source

Effects of cyclic adenosine 3,5-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation. [PDF]

, 1982
As a test of the hypothesis that cyclic nucleotides play a role in the regulation of retinomotor movements and disc shedding in the photoreceptor-pigment epithelial complex, we have used an in vitro eyecup preparation that sustains both disc shedding and
Besharse, J, BURNSIDE, Beth, Dunis, D
core   +1 more source