Results 101 to 110 of about 19,108 (270)

Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro

Journal of Cell Biology, 1982
To compare the effects of cytochalasins on the cellular level with those on the molecular level, 24 cytochalasins, 20 natural compounds and 4 derivatives, were used. The following effects were tested for each of 24 cytochalasins; (a) four high dose (2-20
I. Yahara, F. Harada, S. Sekita, K. Yoshihira, S. Natori   +4 more
semanticscholar   +1 more source

Mechanical Force Promotes Mitochondrial Transfer From Macrophages to BMSCs to Enhance Bone Formation

Cell Proliferation, EarlyView.
Mechanical tension activates Drp1‐mediated mitochondrial fission in macrophages, facilitating the release of Mito‐EVs that are subsequently transferred to BMSCs. Additionally, the CD200R‐CD200 interaction enhances the uptake of these mechanically stimulated macrophage‐derived Mito‐EVs by BMSCs, ultimately promoting osteogenic differentiation.
Yingyi Li, Ziwei Yan, Yueming Dai, Hanjia Cai, Yue Chen, Yuyi Chen, Ruofan Jin, Wen Sun, Hua Wang   +8 more
wiley   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Looking at cell mechanics with atomic force microscopy: Experiment and theory [PDF]

, 2014
This review reports on the use of the atomic force microscopy in the investigation of the mechanical properties of cells. It is shown that the technique is able to deliver information about the cell surface properties (e.g., topography), the Young ...
Alcaraz, Alessandrini, Almqvist, Arnoldi, Azeloglu, Benitez, Borkovec, Bornschlögl, Braunstein, Camesano, Costa, Costa, Crick, Cross, Cumpsen, Dhahri, Doktycz, Ducker, Fischel, Fisher, Florin, Gaboriaud, Garcia, Grimellec, Harris, Henderson, Hinterdorfer, Hobbs, Hoh, Hugel, Johnson, Ketene, Landingham, Longo, Lu, Luque, Maugis, Melzak, Melzak, Melzak, Mendez-Vilas, Moeendarbary, Moreno Flores, Moreno-Flores, Moreno-Flores, Mosier, Murphy, Pietuch, Puech, Putman, Radmacher, Radmacher, Radmacher, Raman, Riande, Rotsch, Saravia, Scheuring, Stewart, Style, Sunyer, Titushkin, Vadillo-Rodriguez, Vargas-Pinto, Varghese Chacko, Walter, Zelenskaya, Zimmer   +67 more
core   +1 more source

Traction force generation in Plasmodium sporozoites is modulated by a surface adhesin

Journal of Microscopy, EarlyView.
Abstract Plasmodium sporozoites are the highly polarised and motile forms of the malaria parasite transmitted by mosquitoes to the vertebrate hosts. Sporozoites use myosin motors to generate retrograde flow of actin filaments. These are linked to plasma membrane spanning adhesins, which in turn bind to the extracellular environment, resulting in ...
Johanna Ripp, Dimitri Probst, Mirko Singer, Ulrich S. Schwarz, Friedrich Frischknecht   +4 more
wiley   +1 more source

شاهدی بر وجود جريان پتاسيمی جبرانی تأخيری فوق سريع (IKur) در دو گره سينوسی- دهليزی و دهليزی- بطنی قلب موش صحرايی [PDF]

, 2008
زمينه: گره سينوسی-دهليزی مرکز فعاليت پيس ميکری اوليه قلب می باشد. اگر به هر دليلی، گره سينوسی-دهليزی فعاليت خود را از دست بدهد، گره دهليزی-بطنی فوراً شروع به تنظيم فعاليت های قلب می نمايد.
نیکمرام, محمرضا, یانی, ژوزف   +1 more
core  

Deciphering the biosynthetic pathways of lichen acids

New Phytologist, EarlyView.
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim, Tânia Keiko Shishido, Huong T. Pham, Kyo Bin Kang, Rundong Liu, Matti Wahlsten, Jérôme Collemare, Hyun Park, Soon‐Ok Oh, Hyung‐Ho Ha, Hangun Kim, Jae‐Seoun Hur   +11 more
wiley   +1 more source

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

Molecular Oral Microbiology, EarlyView.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes, Travis J. Chiarelli, Doaa N. Abdallah, Grayson Way, Huiping Zhou, Jason A. Carlyon, Daniel P. Miller   +6 more
wiley   +1 more source

Plasma supplemented with glycine is superior to standard plasma in reducing vascular permeability and organ injury via reduction of inflammation in an experimental traumatic shock model

Transfusion, EarlyView.
Abstract Background While plasma transfusion is a key resuscitation strategy, its mechanisms of benefit beyond coagulopathy correction remain unclear. Solvent detergent plasma, which contains high glycine levels and lacks inflammatory mediators, may offer advantages over fresh frozen plasma by preserving endothelial integrity and reducing inflammation.
Tarık Gözden, Bülent Ergin, Gözdenur Güneş, Ayşegül Kapucu, Nicole Juffermans   +4 more
wiley   +1 more source